Efforts Made to Eliminate Drug-Resistant Malaria and Its Challenges.
Journal
BioMed research international
ISSN: 2314-6141
Titre abrégé: Biomed Res Int
Pays: United States
ID NLM: 101600173
Informations de publication
Date de publication:
2021
2021
Historique:
received:
21
01
2021
accepted:
09
08
2021
entrez:
9
9
2021
pubmed:
10
9
2021
medline:
15
10
2021
Statut:
epublish
Résumé
Since 2000, a good deal of progress has been made in malaria control. However, there is still an unacceptably high burden of the disease and numerous challenges limiting advancement towards its elimination and ultimate eradication. Among the challenges is the antimalarial drug resistance, which has been documented for almost all antimalarial drugs in current use. As a result, the malaria research community is working on the modification of existing treatments as well as the discovery and development of new drugs to counter the resistance challenges. To this effect, many products are in the pipeline and expected to be marketed soon. In addition to drug and vaccine development, mass drug administration (MDA) is under scientific scrutiny as an important strategy for effective utilization of the developed products. This review discusses the challenges related to malaria elimination, ongoing approaches to tackle the impact of drug-resistant malaria, and upcoming antimalarial drugs.
Identifiants
pubmed: 34497848
doi: 10.1155/2021/5539544
pmc: PMC8421183
doi:
Substances chimiques
Antimalarials
0
Drugs, Investigational
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
5539544Informations de copyright
Copyright © 2021 Wote Amelo and Eyasu Makonnen.
Déclaration de conflit d'intérêts
The authors declare that they have no competing interest.
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