TET-Like Oxidation in 5-Methylcytosine and Derivatives: A Computational and Experimental Study.
5-methylcytosine
DNA methylation
computational chemistry
epigenetics
synthetic biology
Journal
Chembiochem : a European journal of chemical biology
ISSN: 1439-7633
Titre abrégé: Chembiochem
Pays: Germany
ID NLM: 100937360
Informations de publication
Date de publication:
02 12 2021
02 12 2021
Historique:
revised:
08
09
2021
received:
15
08
2021
pubmed:
10
9
2021
medline:
26
2
2022
entrez:
9
9
2021
Statut:
ppublish
Résumé
The epigenetic marker 5-methylcytosine (5mC) is an important factor in DNA modification and epigenetics. It can be modified through a three-step oxidation performed by ten-eleven-translocation (TET) enzymes and we have previously reported that the iron(IV)-oxo complex [Fe(O)(Py
Identifiants
pubmed: 34498783
doi: 10.1002/cbic.202100420
pmc: PMC9293240
doi:
Substances chimiques
Iron Compounds
0
Uracil
56HH86ZVCT
5-Methylcytosine
6R795CQT4H
DNA
9007-49-2
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3333-3340Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : SFB 1309-325871075
Organisme : Studienstiftung des Deutschen Volkes
Informations de copyright
© 2021 The Authors. ChemBioChem published by Wiley-VCH GmbH.
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