Exogenous administration of hydrogen sulfide alleviates homocysteine induced inflammation in ARPE-19 cells.

Animals Cells, Cultured Cystathionine beta-Synthase / biosynthesis Gene Expression Regulation Homocysteine / adverse effects Hydrogen Sulfide / pharmacology Inflammation / chemically induced Retinitis / chemically induced Signal Transduction
AMD CBS CSE H(2)S Inflammation

Journal

Experimental eye research
ISSN: 1096-0007
Titre abrégé: Exp Eye Res
Pays: England
ID NLM: 0370707

Informations de publication

Date de publication:
11 2021
Historique:
received: 16 02 2021
revised: 21 08 2021
accepted: 01 09 2021
pubmed: 10 9 2021
medline: 16 12 2021
entrez: 9 9 2021
Statut: ppublish

Résumé

Plasma homocysteine (Hcy) is an independent risk factor for Age related macular degeneration (AMD) and an inducer of inflammation. Homocysteine catabolism releases hydrogen sulfide (H

Identifiants

DOI: 10.1016/j.exer.2021.108759 PMID: 34499917
pubmed: 34499917
pii: S0014-4835(21)00325-0
doi: 10.1016/j.exer.2021.108759
pii:
doi:

Substances chimiques

Homocysteine 0LVT1QZ0BA
Cystathionine beta-Synthase EC 4.2.1.22
Hydrogen Sulfide YY9FVM7NSN

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

108759

Informations de copyright

Copyright © 2021 Elsevier Ltd. All rights reserved.

Auteurs

Ramya Ravi (R)

R.S. Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, Chennai, 600006, India; School of Chemical and Biotechnology, SASTRA Deemed to Be University, Thanjavur, India.

Anand Kumaraswamy (A)

R.S. Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, Chennai, 600006, India.

Preeti Chauhan (P)

Department of Chemistry, Indian Institute of Science Education and Research Pune, Dr. Homi Bhabha Road, Pashan Pune, 411 008, Maharashtra, India.

Bharathidevi Subramaniam Rajesh (B)

R.S. Mehta Jain Department of Biochemistry and Cell Biology, KBIRVO, Vision Research Foundation, Sankara Nethralaya, Chennai, 600006, India. Electronic address: drbarathi@snmail.org.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › Cellules › Cellules cultivées › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Lyases › Carbon-oxygen lyases › Hydro-lyases › Cystathionine beta-synthase › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés soufrés › Homocystéine › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › Produits chimiques inorganiques › Sulfure d'hydrogène › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › Maladies de l'oeil › Rétinopathies › Rétinite › Exogenous administration of hydrogen sulfide...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Exogenous administration of hydrogen sulfide...