Nocturnal Oxygen Saturation Parameters as Independent Risk Factors for Type 2 Diabetes Mellitus among Obstructive Sleep Apnea Patients.
O2 saturation
hypoxia
obstructive sleep apnea (OSA)
polysomnography (PSG)
risk factor
type 2 diabetes mellitus (DM2)
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
24 Aug 2021
24 Aug 2021
Historique:
received:
20
07
2021
revised:
17
08
2021
accepted:
18
08
2021
entrez:
10
9
2021
pubmed:
11
9
2021
medline:
11
9
2021
Statut:
epublish
Résumé
Obstructive sleep apnea (OSA) is a recognized independent risk factor for metabolic disorders, type 2 diabetes mellites (DM2) in particular. Therefore, the study aimed to assess the influence of nocturnal oxygen saturation parameters on the onset of DM2 among OSA patients. The study consisted of 549 participants, who underwent polysomnography examination. Based on apnea hypopnea index (AHI), 465 patients were diagnosed with OSA. One hundred and seven individuals had comorbid DM2. Cox regression models were used to assess the effect of oxygen saturation parameters on the onset of DM2. Classification and regression trees (CART) analysis was used to assess the onset of the DM2 in the study group in context of oxygen saturation variables. One-way Cox regression showed higher risk of earlier DM2 for increased values of BMI, AHI, decreased basal O
Identifiants
pubmed: 34501217
pii: jcm10173770
doi: 10.3390/jcm10173770
pmc: PMC8432118
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Polish Ministry of Science and Higher Education
ID : 0067/DIA/2018/47
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