Spinal Cord Motion in Degenerative Cervical Myelopathy: The Level of the Stenotic Segment and Gender Cause Altered Pathodynamics.
automated segmentation
convolutional neural network
degenerative cervical myelopathy
gender
phase-contrast MRI
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
25 Aug 2021
25 Aug 2021
Historique:
received:
15
07
2021
revised:
18
08
2021
accepted:
20
08
2021
entrez:
10
9
2021
pubmed:
11
9
2021
medline:
11
9
2021
Statut:
epublish
Résumé
In degenerative cervical myelopathy (DCM), focally increased spinal cord motion has been observed for C5/C6, but whether stenoses at other cervical segments lead to similar pathodynamics and how severity of stenosis, age, and gender affect them is still unclear. We report a prospective matched-pair controlled trial on 65 DCM patients. A high-resolution 3D T2 sampling perfection with application-optimized contrasts using different flip angle evolution (SPACE) and a phase-contrast magnetic resonance imaging (MRI) sequence were performed and automatically segmented. Anatomical and spinal cord motion data were assessed per segment from C2/C3 to C7/T1. Spinal cord motion was focally increased at a level of stenosis among patients with stenosis at C4/C5 (
Identifiants
pubmed: 34501236
pii: jcm10173788
doi: 10.3390/jcm10173788
pmc: PMC8432264
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Deutsche Wirbelsäulenstiftung
ID : 12/2017
Organisme : "Clinical Studies 2019" of the Faculty of Medicine, University of Freiburg, Germany
ID : 3091331904
Références
Spine J. 2014 Oct 1;14(10):2344-54
pubmed: 24462810
Spinal Cord. 1996 Jul;34(7):422-6
pubmed: 8963998
Skeletal Radiol. 2012 Dec;41(12):1543-6
pubmed: 22426774
J Chiropr Med. 2016 Jun;15(2):155-63
pubmed: 27330520
Neurosurgery. 2020 Mar 1;86(3):E292-E299
pubmed: 31792501
Nat Rev Neurol. 2020 Feb;16(2):108-124
pubmed: 31974455
Spine (Phila Pa 1976). 2014 Dec 15;39(26):2136-42
pubmed: 25271503
J Clin Med. 2020 Aug 06;9(8):
pubmed: 32781513
Invest Radiol. 1998 Mar;33(3):141-5
pubmed: 9525752
Sci Rep. 2019 May 15;9(1):7415
pubmed: 31092891
Neuroimage Clin. 2021;30:102580
pubmed: 33578322
Neuroscientist. 2013 Aug;19(4):409-21
pubmed: 23204243
AJNR Am J Neuroradiol. 2021 Mar;42(3):597-609
pubmed: 33541903
Spine (Phila Pa 1976). 2015 Jun 15;40(12):E675-93
pubmed: 25839387
Global Spine J. 2017 Sep;7(3 Suppl):70S-83S
pubmed: 29164035
BMJ. 2018 Feb 22;360:k186
pubmed: 29472200
J Spinal Cord Med. 2011 Nov;34(6):547-54
pubmed: 22330109
Neurosurg Focus. 2016 Jun;40(6):E5
pubmed: 27246488
J Orthop Surg Res. 2019 Oct 12;14(1):321
pubmed: 31606049
J Neurosurg Spine. 2009 Aug;11(2):112-8
pubmed: 19769490
World Neurosurg. 2017 Dec;108:112-117
pubmed: 28807778
PLoS One. 2015 Apr 02;10(4):e0123022
pubmed: 25837285
Spinal Cord. 2018 Aug;56(8):769-776
pubmed: 29497178
Global Spine J. 2018 Aug;8(5):527-534
pubmed: 30258760
Neurosurgery. 2021 Feb 16;88(3):584-591
pubmed: 33289519
Rofo. 2014 Nov;186(11):1016-21
pubmed: 24756427
Radiology. 1994 Jul;192(1):117-21
pubmed: 8208922
Magn Reson Med. 2007 Jul;58(1):185-9
pubmed: 17659610