Effectiveness of a Three-Week Inpatient Pulmonary Rehabilitation Program for Patients after COVID-19: A Prospective Observational Study.


Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
26 08 2021
Historique:
received: 23 07 2021
revised: 19 08 2021
accepted: 21 08 2021
entrez: 10 9 2021
pubmed: 11 9 2021
medline: 15 9 2021
Statut: epublish

Résumé

For COVID-19 patients who remain symptomatic after the acute phase, pulmonary rehabilitation (PR) is recommended. However, only a few studies have investigated the effectiveness of PR, especially considering the duration between the acute phase of COVID-19 and the onset of rehabilitation, as well as the initial severity. This prospective observational study evaluated the efficacy of PR in patients after COVID-19. A total of 120 still-symptomatic patients referred for PR after overcoming acute COVID-19 were asked to participate, of whom 108 (mean age 55.6 ± 10.1 years, 45.4% female) consented. The patients were assigned to three groups according to the time of referral and initial disease severity (severe acute; severe after interval; mild after interval). The primary outcome was dyspnea. Secondary outcomes included other respiratory disease symptoms, physical capacity, lung function, fatigue, quality of life (QoL), depression, and anxiety. Furthermore, patients rated the overall effectiveness of PR and their subjective change in health status. At the end of PR, we detected improvements with large effect sizes in exertional dyspnea, physical capacity, QoL, fatigue, and depression in the overall group. Other parameters changed with small to medium effect sizes. PR was effective after acute COVID-19 in all three groups analyzed.

Identifiants

pubmed: 34501596
pii: ijerph18179001
doi: 10.3390/ijerph18179001
pmc: PMC8430843
pii:
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Déclaration de conflit d'intérêts

M.C.H., M.L., S.M., G.S., K.J. and K.S. are employees of the Bad Reichenhall Clinic. D.N. and M.S. declare no conflict of interest.

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Auteurs

Markus C Hayden (MC)

Bad Reichenhall Clinic, Centre for Rehabilitation, Pulmonology and Orthopedics, 83435 Bad Reichenhall, Germany.

Matthias Limbach (M)

Bad Reichenhall Clinic, Centre for Rehabilitation, Pulmonology and Orthopedics, 83435 Bad Reichenhall, Germany.

Michael Schuler (M)

Institute for Clinical Epidemiology and Biometry, University of Würzburg, 97080 Würzburg, Germany.
University of Applied Science, hs Gesundheit Bochum, 44801 Bochum, Germany.

Steffen Merkl (S)

Bad Reichenhall Clinic, Centre for Rehabilitation, Pulmonology and Orthopedics, 83435 Bad Reichenhall, Germany.

Gabriele Schwarzl (G)

Bad Reichenhall Clinic, Centre for Rehabilitation, Pulmonology and Orthopedics, 83435 Bad Reichenhall, Germany.

Katalin Jakab (K)

Bad Reichenhall Clinic, Centre for Rehabilitation, Pulmonology and Orthopedics, 83435 Bad Reichenhall, Germany.

Dennis Nowak (D)

Comprehensive Pneumology Center Munich (CPC), German Center for Lung for Lung Research (DZL), Institute and Clinic for Occupational, Social and Environmental Medicine, Clinic of the University of Munich, 80336 München, Germany.

Konrad Schultz (K)

Bad Reichenhall Clinic, Centre for Rehabilitation, Pulmonology and Orthopedics, 83435 Bad Reichenhall, Germany.

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