ACTN3 Genotypes and Their Relationship with Muscle Mass and Function of Kosovan Adults.


Journal

International journal of environmental research and public health
ISSN: 1660-4601
Titre abrégé: Int J Environ Res Public Health
Pays: Switzerland
ID NLM: 101238455

Informations de publication

Date de publication:
30 08 2021
Historique:
received: 30 07 2021
revised: 21 08 2021
accepted: 27 08 2021
entrez: 10 9 2021
pubmed: 11 9 2021
medline: 28 10 2021
Statut: epublish

Résumé

Maintaining muscle mass and function is important throughout the lifestyle. While environmental factors such as physical activity and healthy nutrition are well investigated, the contribution of genetic factors is still controversial. Therefore, we aimed to investigate the impact of a common ACTN3 polymorphism (rs1815739) on body composition, handgrip strength, knee extensor peak torque, and physical performance (gait speed, 30-s arm curl, 30-s chair stand) in Kosovan adults. In total, 308 participants (160 females and 148 males, age range from 40 to 91 years) took part in this cross-sectional study. Genomic DNA was extracted from saliva and assessed for ACTN3 genotype distribution (41.5% of RR, 53.9% of RX and 4.6% of XX). Genotype allocation did not account for differences in any of the variables. Interestingly, female XX carriers were taller (

Identifiants

pubmed: 34501725
pii: ijerph18179135
doi: 10.3390/ijerph18179135
pmc: PMC8431689
pii:
doi:

Substances chimiques

ACTN3 protein, human 0
Actinin 11003-00-2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Arben Boshnjaku (A)

Centre for Sport Science and University Sports, University of Vienna, Auf der Schmelz 6, 1150 Vienna, Austria.
Faculty of Medicine, University "Fehmi Agani" in Gjakova, Ismail Qemali n.n., 50000 Gjakovë, Kosovo.

Ermira Krasniqi (E)

Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Althanstraße 14, 1090 Vienna, Austria.
Research Platform Active Ageing, University of Vienna, Althanstraße 14, 1090 Vienna, Austria.

Harald Tschan (H)

Centre for Sport Science and University Sports, University of Vienna, Auf der Schmelz 6, 1150 Vienna, Austria.

Barbara Wessner (B)

Centre for Sport Science and University Sports, University of Vienna, Auf der Schmelz 6, 1150 Vienna, Austria.
Research Platform Active Ageing, University of Vienna, Althanstraße 14, 1090 Vienna, Austria.

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Classifications MeSH