Thermodynamic effect of RNA virus infection on the human cardiovascular system.
Cardiovascular system
Exergetic efficiency
RNA virus
Second law
Thermodynamics
Journal
Journal of thermal biology
ISSN: 0306-4565
Titre abrégé: J Therm Biol
Pays: England
ID NLM: 7600115
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
28
02
2021
revised:
03
06
2021
accepted:
25
06
2021
entrez:
10
9
2021
pubmed:
11
9
2021
medline:
21
1
2022
Statut:
ppublish
Résumé
In this work, analysis of cardiovascular system under the influence of RNA virus infection has been performed from a thermodynamic perspective. An exergetic efficiency of the system has been defined for this purpose. Results show that except for asymptomatic case, the exergetic efficiency reduces as the viral load goes up. Dynamics of viral growth along with change in efficiency is examined under different parameters such as virus production rate, infectivity rate and cell death rate. Results show that the drop in the exergetic efficiency of cardiovascular system under viral infection can be up to about 20%. Under infection, the exergy requirement of the lungs increases significantly as the work rate required by lungs increase by up to 240%.
Identifiants
pubmed: 34503786
pii: S0306-4565(21)00207-2
doi: 10.1016/j.jtherbio.2021.103039
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
103039Informations de copyright
Copyright © 2021 Elsevier Ltd. All rights reserved.