Perfluorocarbon nanomaterials for photodynamic therapy.
Fluorous
Micelle
Nanoemulsion
Perfluorocarbon
Photodynamic therapy
Singlet oxygen
Journal
Current opinion in colloid & interface science
ISSN: 1359-0294
Titre abrégé: Curr Opin Colloid Interface Sci
Pays: England
ID NLM: 9614964
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
entrez:
10
9
2021
pubmed:
11
9
2021
medline:
11
9
2021
Statut:
ppublish
Résumé
Photodynamic therapy (PDT) is a treatment modality in which a photosensitizer is irradiated with light, producing reactive oxygen species, often via energy transfer with oxygen. As it is common for tumors to be hypoxic, methods to deliver photosensitizer and oxygen are desirable. One such approach is the use of perfluorocarbons, molecules in which all C-H bonds are replaced with C-F bonds, to co-deliver oxygen because of the high solubility of gases in perfluorocarbons. This review highlights the benefits and limitations of several fluorinated nanomaterial architectures for use in PDT.
Identifiants
pubmed: 34504391
doi: 10.1016/j.cocis.2021.101454
pmc: PMC8423349
mid: NIHMS1725332
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM135380
Pays : United States
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this article.
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