Computational Redesign of an ω-Transaminase from


Journal

ACS catalysis
ISSN: 2155-5435
Titre abrégé: ACS Catal
Pays: United States
ID NLM: 101562209

Informations de publication

Date de publication:
03 Sep 2021
Historique:
received: 06 05 2021
revised: 26 07 2021
entrez: 10 9 2021
pubmed: 11 9 2021
medline: 11 9 2021
Statut: ppublish

Résumé

ω-Transaminases (ω-TA) are attractive biocatalysts for the production of chiral amines from prochiral ketones

Identifiants

pubmed: 34504735
doi: 10.1021/acscatal.1c02053
pmc: PMC8419838
doi:

Types de publication

Journal Article

Langues

eng

Pagination

10733-10747

Informations de copyright

© 2021 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Qinglong Meng (Q)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.

Carlos Ramírez-Palacios (C)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.
Molecular Dynamics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, AG Groningen 9747, Groningen, The Netherlands.

Nikolas Capra (N)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.

Mattijs E Hooghwinkel (ME)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.

Sebastian Thallmair (S)

Molecular Dynamics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, AG Groningen 9747, Groningen, The Netherlands.
Frankfurt Institute for Advanced Studies, Ruth-Moufang-Str. 1, Frankfurt am Main 60438, Germany.

Henriëtte J Rozeboom (HJ)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.

Andy-Mark W H Thunnissen (AWH)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.

Hein J Wijma (HJ)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.

Siewert J Marrink (SJ)

Molecular Dynamics, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, AG Groningen 9747, Groningen, The Netherlands.

Dick B Janssen (DB)

Biotransformation and Biocatalysis, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 4, AG Groningen 9747, Groningen, The Netherlands.

Classifications MeSH