Early discharge and hospital-assisted home care is associated with better neurodevelopmental outcome in preterm infants.


Journal

Early human development
ISSN: 1872-6232
Titre abrégé: Early Hum Dev
Pays: Ireland
ID NLM: 7708381

Informations de publication

Date de publication:
10 2021
Historique:
received: 08 02 2021
revised: 24 06 2021
accepted: 09 08 2021
pubmed: 11 9 2021
medline: 5 4 2022
entrez: 10 9 2021
Statut: ppublish

Résumé

To compare hospital-assisted neonatal home care and standard hospital care for preterm newborns on neurodevelopment at 2 years corrected age, as well as duration of hospitalization, breastmilk rates, and readmissions before 1 year. This observational study enrolled 415 inborn neonates <34 At two years corrected age, infants in home care had 61% less risk of overall low ASQ ≤220 (OR = 0.4 [0.3-0.5], p < 0.001) and 31-80% less risk of low scores in four out of five domains compared to standard care. Home care was associated with shorter hospital stays (- 9 days; p < 0.001), higher breastmilk rates at final discharge (OR = 3.6 [2.8-4.6], p < 0.001 for singletons and OR = 2.3 [1.6-3.1], p < 0.001 for multiples), and more breastmilk feeding for at least six months (OR = 1.8 [1.3-2.3], p < 0.001 for singletons, OR = 3.6 [2.1-6.3], p < 0.001 for multiples). Readmissions also occurred less frequently with home care than with standard care, except for twins (OR = 0.7 [0.6-0.8], p < 0.001). Hospital-assisted neonatal home care for preterm infants was associated with better neurodevelopment at 2 years corrected age, shorter duration of hospitalization, and higher rates of breastmilk feeding at 6 months.

Identifiants

pubmed: 34507020
pii: S0378-3782(21)00150-X
doi: 10.1016/j.earlhumdev.2021.105451
pii:
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

105451

Informations de copyright

Copyright © 2021. Published by Elsevier B.V.

Auteurs

Jennifer-Laurence Losbar (JL)

Department of Neonatal Medicine, Children's Hospital, Toulouse, France. Electronic address: jlaulosbar@gmail.com.

Nathalie Montjaux (N)

Department of Neonatal Medicine, Children's Hospital, Toulouse, France.

Virginie Ehlinger (V)

Center for Epidemiology and Research in POPulation health (CERPOP), Toulouse University, Inserm, UPS, Toulouse, France.

Laurence Germany (L)

INSERM, UMR 1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), F-94807, Villejuif, France.

Catherine Arnaud (C)

Center for Epidemiology and Research in POPulation health (CERPOP), Toulouse University, Inserm, UPS, Toulouse, France; Clinical Epidemiology Unit, Toulouse University Hospital, Toulouse, France.

Charlotte Tscherning (C)

Université de Toulouse III, Toulouse, France; Division of Neonatology, Sidra Medecine, Weill Cornell Medical College, Doha, Qatar; Centre of Physiopathology Toulouse-Purpan (CPTP), Inserm, CNRS, University of Toulouse, France.

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Classifications MeSH