Interoception and Obsessive-Compulsive Disorder: A Review of Current Evidence and Future Directions.
disgust
evidence-based treatment
interoception
obsessive-compulsive disorder
sensory phenomena
Journal
Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006
Informations de publication
Date de publication:
2021
2021
Historique:
received:
26
03
2021
accepted:
31
07
2021
entrez:
13
9
2021
pubmed:
14
9
2021
medline:
14
9
2021
Statut:
epublish
Résumé
Disrupted interoceptive processes are present in a range of psychiatric conditions, and there is a small but growing body of research on the role of interoception in obsessive-compulsive disorder (OCD). In this review, we outline dimensions of interoception and review current literature on the processing of internal bodily sensations within OCD. Investigations in OCD utilizing objective measures of interoception are limited and results mixed, however, the subjective experience of internal bodily sensations appears to be atypical and relate to specific patterns of symptom dimensions. Further, neuroimaging investigations suggest that interoception is related to core features of OCD, particularly sensory phenomena and disgust. Interoception is discussed in the context of treatment by presenting an overview of existing interventions and suggesting how modifications aimed at better targeting interoceptive processes could serve to optimize outcomes. Interoception represents a promising direction for multi-method research in OCD, which we expect, will prove useful for improving current interventions and identifying new treatment targets.
Identifiants
pubmed: 34512412
doi: 10.3389/fpsyt.2021.686482
pmc: PMC8424053
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
686482Subventions
Organisme : NIMH NIH HHS
ID : R01 MH111794
Pays : United States
Organisme : NIMH NIH HHS
ID : R33 MH107589
Pays : United States
Informations de copyright
Copyright © 2021 Bragdon, Eng, Belanger, Collins and Stern.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Nat Rev Neurosci. 2008 Sep;9(9):720-9
pubmed: 18714327
Neuroimage. 2012 Jan 16;59(2):1441-50
pubmed: 21906689
J Neurosci. 2011 Feb 23;31(8):2948-58
pubmed: 21414916
Brain Imaging Behav. 2018 Oct;12(5):1306-1317
pubmed: 29170944
PLoS One. 2018 Dec 4;13(12):e0208034
pubmed: 30513087
Hum Brain Mapp. 2017 Dec;38(12):6068-6082
pubmed: 28901713
Am J Psychiatry. 2007 Feb;164(2):318-27
pubmed: 17267796
Br J Radiol. 2019 Sep;92(1101):20180942
pubmed: 30855982
Behav Res Ther. 2016 Dec;87:182-187
pubmed: 27716490
Mov Disord. 2015 Aug;30(9):1198-202
pubmed: 25879819
Biol Psychiatry. 2014 Nov 1;76(9):742-9
pubmed: 25038985
J Psychiatr Res. 2021 Apr;136:560-570
pubmed: 33158554
Neuropsychopharmacology. 2019 Jan;44(2):390-398
pubmed: 30116006
Neuroreport. 2004 Oct 25;15(15):2347-51
pubmed: 15640753
Psychiatry Res. 2015 Aug 30;233(2):95-101
pubmed: 26071623
J Psychiatry Neurosci. 2015 Jul;40(4):232-40
pubmed: 25652753
Neuron. 2003 Oct 30;40(3):655-64
pubmed: 14642287
Psychol Med. 2017 Nov;47(15):2578-2586
pubmed: 28478782
PLoS One. 2012;7(11):e48230
pubmed: 23133619
Appl Psychophysiol Biofeedback. 2014 Jun;39(2):109-35
pubmed: 24806535
BMC Psychol. 2015 Aug 05;3:26
pubmed: 26246900
Trends Neurosci. 2021 Jan;44(1):3-16
pubmed: 33378655
Philos Trans R Soc Lond B Biol Sci. 2017 May 26;372(1721):
pubmed: 28396481
Clin Psychol Rev. 2018 Jun;62:37-55
pubmed: 29778929
Mov Disord. 2003 Dec;18(12):1530-3
pubmed: 14673893
Psychol Bull. 2010 Jan;136(1):128-50
pubmed: 20063929
Arch Gen Psychiatry. 2009 Jul;66(7):756-63
pubmed: 19581567
Int J Neuropsychopharmacol. 2006 Feb;9(1):95-100
pubmed: 15982444
Behav Ther. 2013 Sep;44(3):417-31
pubmed: 23768669
J Anxiety Disord. 2007;21(3):445-55
pubmed: 16806801
Trends Cogn Sci. 2009 Aug;13(8):334-40
pubmed: 19643659
PLoS One. 2015 Aug 24;10(8):e0135872
pubmed: 26301829
PLoS One. 2008 Aug 13;3(8):e2939
pubmed: 18698355
J Behav Ther Exp Psychiatry. 2017 Dec;57:113-117
pubmed: 28505489
Eur J Neurosci. 2021 Apr;53(8):2669-2680
pubmed: 33621360
Can J Psychiatry. 2006 Jun;51(7):407-16
pubmed: 16838822
Elife. 2019 Apr 15;8:
pubmed: 30985277
Front Behav Neurosci. 2015 Jun 08;9:148
pubmed: 26106309
Biol Psychiatry Cogn Neurosci Neuroimaging. 2018 Jun;3(6):501-513
pubmed: 29884281
J Clin Psychiatry. 2017 Jul;78(7):e766-e773
pubmed: 28617566
Nat Neurosci. 2009 Dec;12(12):1494-6
pubmed: 19881506
Behav Res Ther. 2007 Sep;45(9):2110-20
pubmed: 17481576
Brain Struct Funct. 2017 May;222(4):1635-1644
pubmed: 27573028
Psychol Assess. 2007 Sep;19(3):281-97
pubmed: 17845120
Eur Eat Disord Rev. 2017 Sep;25(5):411-416
pubmed: 28714581
J Psychiatr Res. 2014 Oct;57:141-8
pubmed: 25012187
Philos Trans R Soc Lond B Biol Sci. 2016 Nov 19;371(1708):
pubmed: 28080970
Cereb Cortex. 2013 Mar;23(3):739-49
pubmed: 22437053
J Consult Clin Psychol. 2018 Nov;86(11):946-960
pubmed: 30335426
J Neurosci. 2007 Feb 28;27(9):2349-56
pubmed: 17329432
Front Psychol. 2015 Jan 06;5:1504
pubmed: 25610410
Brain Struct Funct. 2010 Jun;214(5-6):451-63
pubmed: 20490545
Ment Health Fam Med. 2010 Jun;7(2):85-91
pubmed: 22477926
Cortex. 2017 Jan;86:22-32
pubmed: 27871020
J Abnorm Psychol. 2014 Nov;123(4):695-704
pubmed: 25133987
Nat Neurosci. 2004 Feb;7(2):189-95
pubmed: 14730305
J Dev Behav Pediatr. 2005 Dec;26(6):397-403
pubmed: 16344654
Trends Cogn Sci. 2006 Feb;10(2):59-63
pubmed: 16406760
Biol Psychol. 2015 Jan;104:65-74
pubmed: 25451381
Compr Psychiatry. 2015 Oct;62:141-6
pubmed: 26343478
Cogn Neurosci. 2011 Sep;2(3-4):227-243
pubmed: 22299020
Anxiety. 1996;2(4):167-72
pubmed: 9160618
Neuroimage. 2014 Mar;88:113-24
pubmed: 24231399
Neurosci Lett. 2009 Jun 26;457(2):66-70
pubmed: 19429164
Front Hum Neurosci. 2016 Jul 27;10:379
pubmed: 27512369
Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12569-74
pubmed: 18723676
J Anxiety Disord. 2017 Jan;45:64-71
pubmed: 27960103
Nat Neurosci. 2013 Apr;16(4):386-7
pubmed: 23434914
J Affect Disord. 2020 Nov 1;276:804-814
pubmed: 32738665
Front Psychol. 2016 May 23;7:743
pubmed: 27242642
Neuromodulation. 2019 Dec;22(8):877-883
pubmed: 30370983
Brain Struct Funct. 2010 Jun;214(5-6):435-50
pubmed: 20512364
Compr Psychiatry. 2009 Sep-Oct;50(5):431-6
pubmed: 19683613
PLoS One. 2013 Aug 15;8(8):e71863
pubmed: 23977168
Cereb Cortex. 2009 Jan;19(1):218-23
pubmed: 18469316
Brain. 2020 May 1;143(5):1603-1612
pubmed: 32352147
Psychosom Med. 2001 Sep-Oct;63(5):697-710
pubmed: 11573016
Cortex. 2019 Nov;120:556-566
pubmed: 31525588
J Neurosci. 2000 Apr 1;20(7):2657-63
pubmed: 10729346
J Clin Psychiatry. 2000 Feb;61(2):150-6; quiz 157
pubmed: 10732667
J Obsessive Compuls Relat Disord. 2020 Oct;27:
pubmed: 33194538
Soc Cogn Affect Neurosci. 2013 Mar;8(3):231-4
pubmed: 23482658
J Clin Neurosci. 2021 Aug;90:152-154
pubmed: 34275541
Biol Psychiatry. 2006 Aug 15;60(4):383-7
pubmed: 16780813
J Neuropsychiatry Clin Neurosci. 2012 Fall;24(4):437-43
pubmed: 23224449
Curr Opin Neurobiol. 2003 Aug;13(4):500-5
pubmed: 12965300
Hum Brain Mapp. 2020 Apr 15;41(6):1611-1625
pubmed: 31916668
Psychophysiology. 2008 Jul;45(4):671-7
pubmed: 18503485
Behav Res Ther. 2004 Nov;42(11):1227-55
pubmed: 15381436
Int J Neurosci. 1990 Aug;53(2-4):243-53
pubmed: 2265945
Int J Psychophysiol. 2016 Nov;109:71-80
pubmed: 27702644
J Behav Ther Exp Psychiatry. 2019 Jun;63:12-20
pubmed: 30557753
Behav Res Ther. 2005 Aug;43(8):1069-86
pubmed: 15967177
Behav Modif. 2013 Mar;37(2):170-88
pubmed: 23012685
Neuroimage. 2007 Apr 15;35(3):1238-46
pubmed: 17336094
Psychiatry Res. 2012 May 30;197(3):253-8
pubmed: 22361443
Psychol Med. 2017 Aug;47(11):1957-1970
pubmed: 28374658
Philos Trans R Soc Lond B Biol Sci. 2016 Nov 19;371(1708):
pubmed: 28080973
Anxiety Stress Coping. 2011 Mar;24(2):157-65
pubmed: 20737324
Int J Eat Disord. 2015 Nov;48(7):889-97
pubmed: 25712775
Int J Methods Psychiatr Res. 2018 Jun;27(2):e1596
pubmed: 29193423
Int J Neuropsychopharmacol. 2010 Mar;13(2):217-27
pubmed: 19691873
Behav Res Ther. 2002 Nov;40(11):1243-53
pubmed: 12384321
Int J Psychiatry Clin Pract. 2012 Jun;16(2):77-84
pubmed: 22540422
Brain Res Cogn Brain Res. 2005 Dec;25(3):948-62
pubmed: 16298111
J Psychiatr Res. 2019 Feb;109:68-75
pubmed: 30508745
J Anxiety Disord. 2017 Jan;45:9-16
pubmed: 27886574
Br J Anaesth. 1999 Mar;82(3):439-41
pubmed: 10434832
J Behav Ther Exp Psychiatry. 2006 Mar;37(1):30-40
pubmed: 16226217
Hum Brain Mapp. 2007 Jan;28(1):9-18
pubmed: 16729289
Cereb Cortex. 2011 Jul;21(7):1498-506
pubmed: 21097516
Curr Biol. 2021 Feb 8;31(3):629-634.e3
pubmed: 33238154
Neuropsychopharmacology. 2021 Apr;46(5):1035-1044
pubmed: 33446895
Biol Psychiatry. 2007 May 1;61(9):1072-80
pubmed: 17097073
Behav Res Ther. 1999 Nov;37(11):1055-72
pubmed: 10500320
Hum Brain Mapp. 2009 Sep;30(9):2731-45
pubmed: 19072897
Neuron. 2007 Jul 19;55(2):187-99
pubmed: 17640522
J Behav Ther Exp Psychiatry. 2006 Mar;37(1):53-9
pubmed: 16253206
J Comp Neurol. 1979 Jul 15;186(2):117-31
pubmed: 447880
Neuropsychiatr Dis Treat. 2019 Aug 06;15:2247-2256
pubmed: 31496707
Psychiatry Res. 2005 Jul 30;139(2):101-14
pubmed: 15970434
Nat Rev Neurosci. 2009 Jan;10(1):59-70
pubmed: 19096369
Behav Res Ther. 2004 Jun;42(6):647-70
pubmed: 15081882
Brain Imaging Behav. 2017 Aug;11(4):1117-1128
pubmed: 27704405
Psychol Assess. 2010 Mar;22(1):180-98
pubmed: 20230164
PLoS One. 2019 May 24;14(5):e0217237
pubmed: 31125377
Physiol Behav. 2018 Feb 1;184:100-107
pubmed: 29155249
Psychiatry Res. 2018 Apr;262:6-12
pubmed: 29407570
Neuropsychopharmacology. 2021 Apr;46(5):1028-1034
pubmed: 33452434
Assessment. 2008 Sep;15(3):351-63
pubmed: 18310595
Front Psychol. 2015 Aug 24;6:1202
pubmed: 26379571
Curr Treat Options Psychiatry. 2014 Sep;1(3):235-247
pubmed: 33344105
Perspect Psychol Sci. 2017 Jul;12(4):613-648
pubmed: 28651058
Am J Psychiatry. 2007 Jul;164(7 Suppl):5-53
pubmed: 17849776
Top Cogn Sci. 2012 Oct;4(4):692-704
pubmed: 22389201
J Am Acad Child Adolesc Psychiatry. 2006 Apr;45(4):383; author reply 383-4
pubmed: 16601639
Behav Res Ther. 1985;23(5):571-83
pubmed: 4051930
Nat Neurosci. 2004 Feb;7(2):102-3
pubmed: 14747831
Psychol Bull. 1986 Jan;99(1):20-35
pubmed: 2871574
Behav Res Ther. 2003 Jun;41(6):681-700
pubmed: 12732376
Philos Trans R Soc Lond B Biol Sci. 2016 Nov 19;371(1708):
pubmed: 28080961
Biol Psychiatry. 2021 Nov 15;90(10):701-713
pubmed: 34134839
Neurosci Lett. 2019 Mar 23;696:108-113
pubmed: 30572103
JAMA Psychiatry. 2016 May 1;73(5):490-6
pubmed: 27007062
Neuroimage. 2011 Mar 1;55(1):8-23
pubmed: 21111053
Behav Ther. 2014 Mar;45(2):254-62
pubmed: 24491200
J Anxiety Disord. 2011 Oct;25(7):932-8
pubmed: 21696916
Neuroimage. 2012 May 1;60(4):1947-58
pubmed: 22361166
Brain Stimul. 2013 Jan;6(1):1-13
pubmed: 22483681
Trends Neurosci. 2021 Jan;44(1):17-28
pubmed: 33378653
Front Psychiatry. 2016 Jul 25;7:121
pubmed: 27504098
Hum Brain Mapp. 2020 Aug 1;41(11):2898-2908
pubmed: 32216126
Clin Psychol Rev. 2009 Feb;29(1):34-46
pubmed: 18977061
Psychophysiology. 1993 Sep;30(5):467-74
pubmed: 8416073
Brain Struct Funct. 2010 Jun;214(5-6):655-67
pubmed: 20512370
Psychol Rev. 1962 Sep;69:379-99
pubmed: 14497895
Br J Psychiatry. 2007 Jun;190:457-9
pubmed: 17541102
CNS Spectr. 2009 Jun;14(6):315-23
pubmed: 19668122
Int J Psychophysiol. 2007 Sep;65(3):214-27
pubmed: 17543405
Cereb Cortex. 2013 Jan;23(1):114-26
pubmed: 22267308
Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19816-21
pubmed: 23150550
J Anxiety Disord. 2009 Jan;23(1):118-23
pubmed: 18541403
Psychol Rev. 1987 Jan;94(1):23-41
pubmed: 3823304
Neuron. 2013 Feb 20;77(4):624-38
pubmed: 23439117
J Med Internet Res. 2020 Jul 23;22(7):e14958
pubmed: 32706654
Clin Neurophysiol. 2005 Apr;116(4):775-9
pubmed: 15792886
Am J Psychiatry. 2021 Jan 1;178(1):17-29
pubmed: 33384007
Int J Methods Psychiatr Res. 2012 Sep;21(3):169-84
pubmed: 22865617
Psychol Assess. 2007 Jun;19(2):176-88
pubmed: 17563199
Acta Psychiatr Scand. 2021 Apr;143(4):307-318
pubmed: 33492682
Trends Neurosci. 2017 Apr;40(4):200-207
pubmed: 28314446
Soc Cogn Affect Neurosci. 2012 Aug;7(6):623-34
pubmed: 21983794
Behav Brain Funct. 2015 Apr 08;11:14
pubmed: 25889157
Behav Res Ther. 2008 Aug;46(8):895-904
pubmed: 18514616
Psychol Assess. 2015 Sep;27(3):1123-1128
pubmed: 25894700
J Affect Disord. 2017 Jan 01;207:148-156
pubmed: 27721189
Hum Brain Mapp. 2013 Nov;34(11):2944-58
pubmed: 22696421
Compr Psychiatry. 2006 Jul-Aug;47(4):276-81
pubmed: 16769302
Mov Disord. 2015 Aug;30(9):1190-7
pubmed: 25855089
J Neurosci. 2010 Sep 22;30(38):12878-84
pubmed: 20861391
Behav Res Ther. 1999 Apr;37(4):297-311
pubmed: 10204276
Curr Biol. 2014 Dec 1;24(23):R1111-6
pubmed: 25465326
Behav Res Ther. 2008 Jan;46(1):5-27
pubmed: 18005936
Nat Rev Neurosci. 2002 Aug;3(8):655-66
pubmed: 12154366
J Anxiety Disord. 2006;20(7):837-57
pubmed: 16466904
J Anxiety Disord. 2010 Jan;24(1):63-70
pubmed: 19747796
Neuroimage. 2002 Feb;15(2):293-301
pubmed: 11798266
Am J Psychiatry. 2021 Jan 1;178(1):39-47
pubmed: 32854533
Biol Psychiatry. 2003 Oct 1;54(7):751-6
pubmed: 14512216
Behav Ther. 2008 Sep;39(3):224-31
pubmed: 18721636
Behav Res Ther. 1986;24(1):1-8
pubmed: 3947307
PLoS One. 2015 Jul 24;10(7):e0133591
pubmed: 26208305
Psychiatry Res. 2019 Jan;271:469-475
pubmed: 30544073
Lancet. 1985 May 11;1(8437):1106-7
pubmed: 2860322
J Clin Psychiatry. 2013 Mar;74(3):233-9
pubmed: 23561228
J Child Psychol Psychiatry. 2020 Sep;61(9):979-987
pubmed: 31950513
Int J Psychophysiol. 2005 Jul;57(1):69-77
pubmed: 15935263