[Factors predicting the need for invasive mechanical ventilation in patients with chronic obstructive pulmonary disease (COPD)].
Facteurs prédictifs de la ventilation mécanique invasive chez les patients atteints de broncho-pneumopathie chronique obstructive (BPCO).
Aged
Disease Progression
Female
Hospitalization
/ statistics & numerical data
Humans
Hydrogen-Ion Concentration
Hypercapnia
/ epidemiology
Male
Middle Aged
Noninvasive Ventilation
/ statistics & numerical data
Pulmonary Disease, Chronic Obstructive
/ physiopathology
Respiration, Artificial
/ statistics & numerical data
Retrospective Studies
Risk Factors
Severity of Illness Index
Chronic obstructive pulmonary disease
acute exacerbation
mechanical ventilation
predictive factors
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2021
2021
Historique:
received:
20
12
2020
accepted:
15
05
2021
entrez:
13
9
2021
pubmed:
14
9
2021
medline:
8
10
2021
Statut:
epublish
Résumé
the use of invasive mechanical ventilation (IMV) in acute exacerbations of chronic obstructive pulmonary disease (AECOPD) constitutes a negative turning point in the progression of the disease. The purpose of this study is to determine factors predicting the need for IMV in AECOPD. we conducted a retrospective study by reviewing the medical records of patients with AECOPD hospitalized in our Department over a 18-year period (2000-2017). We compared 2 groups: G1: patients with AECOPD undergoing at least one IMV and G2: patients who had never undergone IMV following AECOPD. the study included 1152 patients with COPD: 133 in the G1 group (11.5%), and 1019 in the G2 group (88.5%). G1 patients were more symptomatic (p < 0.001), with more severe bronchial obstruction (p < 0.001). G1 patients had more exacerbations (p < 0.001), more hospitalizations and a higher need for non-invasive ventilation (NIV) (p < 0.001). Similarly, G1 patients more often developed chronic respiratory failure (p < 0.001) and had significantly lower survival rates. Independent risk factors associated with IMV were hypercapnia and decreased pH (in patients with severe AECOPD), a history of NIV, and chronic respiratory failure (CRF). respiratory function impairment, the severity of exacerbation and the need for NIV in a previous episode are factors predicting the need for IMV and poor outcomes.
Identifiants
pubmed: 34512855
doi: 10.11604/pamj.2021.39.119.27514
pii: PAMJ-39-119
pmc: PMC8396382
doi:
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
119Informations de copyright
Copyright: Lobna Loued et al.
Déclaration de conflit d'intérêts
Les auteurs ne déclarent aucun conflit d´intérêts.
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