Tune the channel: TRPM8 targeting in prostate cancer.

TRPM8 cancer translational research precision oncology prostate cancer

Journal

Oncoscience
ISSN: 2331-4737
Titre abrégé: Oncoscience
Pays: United States
ID NLM: 101636666

Informations de publication

Date de publication:
2021
Historique:
received: 09 06 2021
accepted: 06 09 2021
entrez: 13 9 2021
pubmed: 14 9 2021
medline: 14 9 2021
Statut: epublish

Résumé

The therapeutic landscape of cancer treatments is quickly evolving thanks to the advent of precision oncology. Discovery of novel druggable targets and more reliable biomarkers is a primary objective towards personalized strategies of cancer treatment. Highly expressed in the prostate epithelium within the human body, Transient Receptor Potential subfamily M member 8 (TRPM8) levels rise in primary and hormone naïve metastatic prostate cancer (PCa) lesions, which makes this channel an interesting prototype of molecular target. Recently, by combining a multidisciplinary approach to an

Identifiants

pubmed: 34514058
doi: 10.18632/oncoscience.543
pii: 543
pmc: PMC8428510
doi:

Types de publication

Journal Article

Langues

eng

Pagination

97-100

Déclaration de conflit d'intérêts

CONFLICTS OF INTEREST Authors have no conflicts of interest to declare.

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Auteurs

Alessandro Alaimo (A)

Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.

Dario De Felice (D)

Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.

Sacha Genovesi (S)

Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.

Marco Lorenzoni (M)

Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.

Andrea Lunardi (A)

Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, Trento 38123, Italy.

Classifications MeSH