Biogeographical Landscape of the Human Face Skin Microbiome Viewed in High Definition.
Journal
Acta dermato-venereologica
ISSN: 1651-2057
Titre abrégé: Acta Derm Venereol
Pays: Sweden
ID NLM: 0370310
Informations de publication
Date de publication:
24 Nov 2021
24 Nov 2021
Historique:
pubmed:
14
9
2021
medline:
27
11
2021
entrez:
13
9
2021
Statut:
epublish
Résumé
The bacterial community that colonizes the human face imparts physiochemical and physiological effects on the facial skin. These skin-microbe interactions impact dermatological, cosmetic and skincare applications due to the centrality of the human face in daily interactions. However, fine-scale characterization of the human face skin microbiome is lacking. Using 16S rRNA sequencing and 3D cartography, this study plotted and characterized the facial skin microbiome in high- definition, based on 1,649 samples from 12 individuals. Analysis yielded a number of novel insights, including that of the relative uniformity of skin microbiome composition within skin sites, site localization of certain microbes, and the interpersonal variability of the skin microbiome. The results show that high-resolution topographical mapping of the skin microbiome is a powerful tool for studying the human skin microbiome. Despite a decade of skin microbiome research, there is still much to be discovered.
Identifiants
pubmed: 34515801
doi: 10.2340/00015555-3929
pmc: PMC9455318
doi:
Substances chimiques
RNA, Ribosomal, 16S
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
adv00603Références
Science. 2009 May 29;324(5931):1190-2
pubmed: 19478181
Appl Environ Microbiol. 2006 Jul;72(7):5069-72
pubmed: 16820507
Case Rep Dermatol. 2017 May 22;9(2):19-25
pubmed: 28611631
Science. 2020 May 29;368(6494):973-980
pubmed: 32467386
Genome Biol. 2011;12(5):R50
pubmed: 21624126
Cell Host Microbe. 2020 Aug 12;28(2):160-168
pubmed: 32791109
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D294-6
pubmed: 15608200
Photochem Photobiol. 2019 Nov;95(6):1446-1453
pubmed: 31074874
Br J Dermatol. 2018 Nov;179(5):1222-1224
pubmed: 29962038
Genome Res. 2008 Jul;18(7):1043-50
pubmed: 18502944
Microbiome. 2018 Jan 26;6(1):17
pubmed: 29373999
Nat Rev Microbiol. 2018 Mar;16(3):143-155
pubmed: 29332945
Cell Host Microbe. 2017 Jul 12;22(1):13-24.e4
pubmed: 28669672
PLoS One. 2013 Apr 22;8(4):e61217
pubmed: 23630581
Nature. 2013 Jun 20;498(7454):367-70
pubmed: 23698366
Genome Med. 2012 Oct 10;4(10):77
pubmed: 23050952
Genome Biol. 2014 Dec 03;15(12):531
pubmed: 25517225
Acta Derm Venereol. 2018 Feb 7;98(2):256-261
pubmed: 28815268
Cell. 2016 May 5;165(4):854-66
pubmed: 27153496
Clin Infect Dis. 2020 Aug 22;71(5):1142-1148
pubmed: 31573026
Int J Oral Sci. 2017 Sep;9(3):145-150
pubmed: 28621325
Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2120-9
pubmed: 25825778
J Invest Dermatol. 2016 Oct;136(10):1950-1954
pubmed: 27377698
J Invest Dermatol. 2018 Oct;138(10):2234-2243
pubmed: 29753031
Nat Rev Microbiol. 2011 Apr;9(4):244-53
pubmed: 21407241
Nat Protoc. 2018 Jan;13(1):134-154
pubmed: 29266099
Cell Host Microbe. 2017 Nov 8;22(5):705-716.e4
pubmed: 29056429
Nature. 2013 Nov 21;503(7476):397-401
pubmed: 24172897
J Invest Dermatol. 2017 Jun;137(6):1213-1214
pubmed: 28395897
Nat Commun. 2013;4:1431
pubmed: 23385576
Nature. 2014 Oct 2;514(7520):59-64
pubmed: 25279917
J Eur Acad Dermatol Venereol. 2020 Apr;34(4):e183-e186
pubmed: 31875978