Determinants of Functional Improvement After Cardiac Rehabilitation in Acute Coronary Syndrome.
Acute coronary syndrome
Cardiac rehabilitation
Functional improvement
Journal
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension
ISSN: 1179-1985
Titre abrégé: High Blood Press Cardiovasc Prev
Pays: New Zealand
ID NLM: 9421087
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
13
06
2021
accepted:
28
08
2021
pubmed:
14
9
2021
medline:
17
12
2021
entrez:
13
9
2021
Statut:
ppublish
Résumé
Cardiac rehabilitation (CR) is an effective tool for secondary prevention after acute coronary syndrome (ACS). Aim of our study was to find the significant determinants of exercise capacity (evaluated with the six-minute walking test-6-MWT) and functional improvement in patients undergoing CR after an ACS. The study group included 298 patients (mean age 61.6 ± 10.2 years; males 80.2%) who, after ACS, were enrolled in CR program at Niguarda Hospital in Milan from 2015 to 2018. For all patients, we collected anamnestic, clinical and instrumental cardiological data. All patients performed a 6-MWT at the beginning (6-MWT-1) and at the end (6-MWT-2) of CR program. Δ meters were used to represent functional improvement. Multiple linear regression models were carried out for 6-MWT-1, 6-MWT-2, Δ meters and % Δ meters. Standardized regression coefficients showed that age (β = - 0.237; p < 0.001), BMI (β = - 0.116; p = 0.006) and heart rate (β = - 0.082; p = 0.040) were determinants of exercise capacity (6MWT-1 and 2), whereas age (β = -.231; p = 0.004), sex (β = - 0.187; p = 0.008) and BMI (β = - 0.164; p = 0.022) were determinants of functional improvement (Δ meters). Our data showed that functional improvement after CR in ACS patients is mainly related to non-cardiological variables. Instead it is related to intrinsic factors, both modifiable (BMI) and non-modifiable (age, sex).
Identifiants
pubmed: 34515960
doi: 10.1007/s40292-021-00473-7
pii: 10.1007/s40292-021-00473-7
pmc: PMC8590661
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
579-587Subventions
Organisme : ministero dell'istruzione, dell'università e della ricerca
ID : Department of Excellence project PREMIA (PREcision MedIcine Approach: bringing biomarker research to clinic)
Informations de copyright
© 2021. The Author(s).
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