Ischemic Stroke and Provoked Seizure as a Manifestation of Brugmansia suaveolens (Angel's Trumpet) Acute Intoxication: A Detailed Clinical, Electroencephalogram, and Magnetic Resonance Imaging Description and 5-Month Follow-up.


Journal

Clinical neuropharmacology
ISSN: 1537-162X
Titre abrégé: Clin Neuropharmacol
Pays: United States
ID NLM: 7607910

Informations de publication

Date de publication:
Historique:
pubmed: 14 9 2021
medline: 17 11 2021
entrez: 13 9 2021
Statut: ppublish

Résumé

We present a detailed clinical, laboratory, electroencephalogram/magnetic resonance imaging description and a 4-month follow-up of a case of stroke and provoked seizures as manifestation of angel's trumpet intoxication. A 76-year-old woman presented with stuporous state evolving in 48 hours in bilateral mydriasis, vomiting, global aphasia, confusion, and stereotyped movement. An interictal electroencephalogram, performed 72 hours later, showed frequent generalized epileptiform discharges, and a brain magnetic resonance imaging revealed 2 small subcortical lesions in the right frontal lobe on diffusion weighted imaging sequences. When completely recovered, she could tell that she had mistaken angel's trumpet flowers for pumpkin flowers, so she had eaten them. Angel's trumpet intoxication is a neurological emergency that deserves attention of both the media in matter of plant poisoning and the scientific forums because of the high lethal potential to better choose the diagnostic and therapeutic process.

Identifiants

pubmed: 34516441
doi: 10.1097/WNF.0000000000000478
pii: 00002826-900000000-99441
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

231-234

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest and Source of Funding: The authors have no conflicts of interest to declare.

Références

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Gopel C, Laufer C, Marcus A. Three cases of angel's trumpet tea-induced psychosis in adolescent substance abusers. Nord J Psychiatry 2002;56:49–52.
Hayman J. Datura poisoning—the angel's trumpet. Pathology 1985;17:465–466.
Greene GS, Patterson SG, Warner E. Ingestion of angel's trumpet: an increasingly common source of toxicity. South Med J 1996;89:365–369.
Kim Y, Kim J, Kim OJ, et al. Intoxication by angel's trumpet: case report and literature review. BMC Res Notes 2014;7:553.
Takeshima S, Neshige S, Hara N, et al. Acute encephalopathy due to angel's trumpet intoxication: a case report and literature review. No to Shinkei 2017;57(5):225–229.
Isbister GK, Oakley P, Dawson AH, et al. Presumed Angel's trumpet (Brugmansia) poisoning: clinical effects and epidemiology. Emerg Med (Fremantle) 2003;15:376–382.
Plenert B, Prasa D, Hentschel H, et al. Plant exposures reported to the Poisons Information Centre Erfurt from 2001–2010. Planta Med 2012;78:401–408.
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