Optogenetic modeling of human neuromuscular circuits in Duchenne muscular dystrophy with CRISPR and pharmacological corrections.


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
10 Sep 2021
Historique:
entrez: 13 9 2021
pubmed: 14 9 2021
medline: 14 9 2021
Statut: ppublish

Résumé

Duchenne muscular dystrophy (DMD) is caused by

Identifiants

pubmed: 34516770
doi: 10.1126/sciadv.abi8787
pmc: PMC8442926
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabi8787

Subventions

Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Medical Research Council
ID : G0802546
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N025865/1
Pays : United Kingdom

Commentaires et corrections

Type : ErratumIn

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Auteurs

Amaia Paredes-Redondo (A)

Centre for Genomics and Child Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK.
Stem Cell Laboratory, National Bowel Research Centre, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 2 Newark Street, London E1 2AT, UK.
Centre for Predictive in vitro Model, Queen Mary University of London, Mile End Road, London E1 4NS, UK.

Peter Harley (P)

Centre for Stem Cells and Regenerative Medicine, MRC Centre for Neurodevelopmental Disorders, and Centre for Developmental Neurobiology, King's College London, London, UK.

Eleni Maniati (E)

Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK.

David Ryan (D)

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

Sandra Louzada (S)

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

Jinhong Meng (J)

UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.

Anna Kowala (A)

Centre for Genomics and Child Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK.
Stem Cell Laboratory, National Bowel Research Centre, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 2 Newark Street, London E1 2AT, UK.
Centre for Predictive in vitro Model, Queen Mary University of London, Mile End Road, London E1 4NS, UK.

Beiyuan Fu (B)

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

Fengtang Yang (F)

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK.

Pentao Liu (P)

School of Biomedical Sciences, Stem Cell and Regenerative Medicine Consortium, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

Silvia Marino (S)

Centre for Genomics and Child Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK.

Olivier Pourquié (O)

Department of Genetics and Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA, USA.

Francesco Muntoni (F)

UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.
NIHR Biomedical Research Centre, Great Ormond Street Hospital, Great Ormond Street, London, UK.

Jun Wang (J)

Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK.

Ivo Lieberam (I)

Centre for Stem Cells and Regenerative Medicine, MRC Centre for Neurodevelopmental Disorders, and Centre for Developmental Neurobiology, King's College London, London, UK.

Yung-Yao Lin (YY)

Centre for Genomics and Child Health, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London E1 2AT, UK.
Stem Cell Laboratory, National Bowel Research Centre, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 2 Newark Street, London E1 2AT, UK.
Centre for Predictive in vitro Model, Queen Mary University of London, Mile End Road, London E1 4NS, UK.

Classifications MeSH