IgG4-related pachymeningitis and mastoiditis, associated with cerebral venous thrombosis: A case report.


Journal

Journal of neuroimmunology
ISSN: 1872-8421
Titre abrégé: J Neuroimmunol
Pays: Netherlands
ID NLM: 8109498

Informations de publication

Date de publication:
15 11 2021
Historique:
received: 25 05 2021
revised: 12 08 2021
accepted: 05 09 2021
pubmed: 14 9 2021
medline: 8 1 2022
entrez: 13 9 2021
Statut: ppublish

Résumé

IgG4-related disease (IgG4-RD) is a multisystem fibroinflammatory condition; this can be a challenging diagnosis that requires clinico-pathologic correlation. We report a young woman, presenting with cranial nerve palsy. The work-up revealed pachymeningitis, cerebral venous thrombosis (CVT), and a destructive lesion in the mastoid. We diagnosed IgG4-RD through mastoidectomy. Thus, a biopsy of asymptomatic, infrequently affected organs, like the mastoid, can meet all histopathological criteria. In neuro-meningeal presentations, CVT may be secondary to the local inflammatory environment of pachymeningitis. Since our patient had a deep vein thrombosis one year prior, we discuss a possible higher risk of thrombosis in IgG4-RD patients.

Identifiants

pubmed: 34517153
pii: S0165-5728(21)00244-7
doi: 10.1016/j.jneuroim.2021.577717
pii:
doi:

Substances chimiques

Adrenal Cortex Hormones 0
Rituximab 4F4X42SYQ6
Dabigatran I0VM4M70GC

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

577717

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Christelle Nilles (C)

Service de Neurologie, Hôpital Fondation Adolphe de Rothschild, Paris, France.

Guillaume Poillon (G)

Service de Radiologie, Hôpital Fondation Adolphe de Rothschild, Paris, France.

Lydia Deschamps (L)

Service d'Anatomopathologie, Hôpital Bichat Claude Bernard, AP-HP, Paris, France.

Mary Daval (M)

Service d'ORL, Hôpital Fondation Adolphe de Rothschild, Paris, France.

Ibrahima Mariam Diallo (IM)

Service de Neurologie, CH Andrée Rosemon, Cayenne, France.

Romain Deschamps (R)

Service de Neurologie, Hôpital Fondation Adolphe de Rothschild, Paris, France.

Marine Boudot de la Motte (M)

Service de Neurologie, Hôpital Fondation Adolphe de Rothschild, Paris, France. Electronic address: mboudotdelamotte@for.paris.

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Classifications MeSH