Complications Associated with Worse Visual Outcomes in Patients with Exudative Neovascular Age-Related Macular Degeneration.


Journal

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
ISSN: 1423-0267
Titre abrégé: Ophthalmologica
Pays: Switzerland
ID NLM: 0054655

Informations de publication

Date de publication:
2021
Historique:
received: 08 05 2021
accepted: 06 09 2021
pubmed: 14 9 2021
medline: 22 12 2021
entrez: 13 9 2021
Statut: ppublish

Résumé

Neovascular age-related macular degeneration (AMD) represents a leading cause of vision loss in older subjects. The introduction of anti-vascular endothelial growth factor therapy has enormously improved the visual prognosis in these patients. However, severe complications may still occur in this disease and their development may significantly affect short- and long-term visual outcomes. Key Messages: In this article, we provided a review of these complications, highlighting their distinctive signs or symptoms and focusing on the current evidence of treatment. To place the complications related to neovascular AMD in a proper context, this review deals with core components essential for proper comprehension of neovascular AMD that includes pathogenesis, clinical signs, and basic principles of treatment.

Sections du résumé

BACKGROUND BACKGROUND
Neovascular age-related macular degeneration (AMD) represents a leading cause of vision loss in older subjects. The introduction of anti-vascular endothelial growth factor therapy has enormously improved the visual prognosis in these patients.
SUMMARY CONCLUSIONS
However, severe complications may still occur in this disease and their development may significantly affect short- and long-term visual outcomes. Key Messages: In this article, we provided a review of these complications, highlighting their distinctive signs or symptoms and focusing on the current evidence of treatment. To place the complications related to neovascular AMD in a proper context, this review deals with core components essential for proper comprehension of neovascular AMD that includes pathogenesis, clinical signs, and basic principles of treatment.

Identifiants

pubmed: 34517374
pii: 000519518
doi: 10.1159/000519518
doi:

Substances chimiques

Angiogenesis Inhibitors 0
Vascular Endothelial Growth Factor A 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

512-522

Informations de copyright

© 2021 S. Karger AG, Basel.

Auteurs

Costanza Barresi (C)

Vita-Salute San Raffaele University Milan, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Milan, Italy.

Enrico Borrelli (E)

Vita-Salute San Raffaele University Milan, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Milan, Italy.

Federico Fantaguzzi (F)

Vita-Salute San Raffaele University Milan, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Milan, Italy.

Domenico Grosso (D)

Vita-Salute San Raffaele University Milan, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Milan, Italy.

Riccardo Sacconi (R)

Vita-Salute San Raffaele University Milan, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Milan, Italy.

Francesco Bandello (F)

Vita-Salute San Raffaele University Milan, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Milan, Italy.

Giuseppe Querques (G)

Vita-Salute San Raffaele University Milan, Milan, Italy.
IRCCS San Raffaele Scientific Institute, Milan, Italy.

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Classifications MeSH