Dynamic changes of scleral spur length in different accommodation stimuli states.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
13 09 2021
13 09 2021
Historique:
received:
19
04
2021
accepted:
30
08
2021
entrez:
14
9
2021
pubmed:
15
9
2021
medline:
15
9
2021
Statut:
epublish
Résumé
This study aimed to evaluate the scleral spur length (SSL) in response to different accommodation stimuli states, as well as the correlation with Schlemm's canal (SC) and trabecular meshwork (TM). 74 children were recruited for this study. The 0D, - 4D, and - 8.0 D accommodation stimuli state was achieved by looking at a variable distance optotype. The ciliary muscle (CM), scleral spur (SS), SC, and TM were imaged by swept-source optical coherence tomography. The SSL (Method III) increased significantly from 221.56 ± 30.74 μm at base state to 234.99 ± 30.11 μm at - 4D accommodation stimuli state (p = 0.028) and increased to 250.09 ± 29.87 μm at - 8D accommodation stimuli state (p = 0.011). Method III had the largest areas under receiver operating characteristic (ROC) curves (0.798, 95% CI 0.721-0.875). Moreover, CM 1, SC, and trabecular meshwork length (TML) were significantly correlated with SSL (Method III) (p < 0.05). These findings suggest that the contractile ability and compliance of the SS play an important role in maintaining the morphology of the SC. Moreover, the force of accommodation regulates the SC size by increasing the length of SS.
Identifiants
pubmed: 34518627
doi: 10.1038/s41598-021-97754-x
pii: 10.1038/s41598-021-97754-x
pmc: PMC8438021
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
18176Informations de copyright
© 2021. The Author(s).
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