Light Chain Glomerulopathy Causing Kidney Failure in Renal Cell Carcinoma.

light cast chain nephropathy light chain deposition disease multiple myeloma renal cell caricnoma systemic capillary leak syndrome

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Sep 2021
Historique:
accepted: 09 09 2021
entrez: 15 9 2021
pubmed: 16 9 2021
medline: 16 9 2021
Statut: epublish

Résumé

Light chain deposition disease (LCDD) is a rare cause of kidney failure. It is associated with multiple myeloma and is diagnosed by the evaluation of serum and urine free light chains. Patients who are diagnosed with this disease often develop rapidly progressive renal failure. To our knowledge, it does not have any association with other malignancies aside from multiple myeloma. We present a case that highlights a novel association between renal cell carcinoma and light chain-mediated renal disease. Our patient was admitted due to acute renal failure and underwent a comprehensive diagnostic evaluation with an eventual diagnosis of light chain glomerulopathy in the setting of metastatic renal cell carcinoma.

Identifiants

pubmed: 34522562
doi: 10.7759/cureus.17850
doi:

Types de publication

Case Reports Retracted Publication

Langues

eng

Pagination

e17850

Subventions

Organisme : NIGMS NIH HHS
ID : T32 GM007337
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM139776
Pays : United States

Commentaires et corrections

Type : RetractionIn

Informations de copyright

Copyright © 2021, Farzam et al.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Auteurs

Khashayar Farzam (K)

Family Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA.

Keyan Zarei (K)

Internal Medicine, University of Iowa Hospitals and Clinics, Iowa City, USA.

Classifications MeSH