A case report: Use of FT-IR analysis to improve Colovesical fistula diagnosis.
Colovesical fistula
Faecaluria
Fourier transform infrared spectroscopy
Journal
Practical laboratory medicine
ISSN: 2352-5517
Titre abrégé: Pract Lab Med
Pays: Netherlands
ID NLM: 101690848
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
30
07
2021
accepted:
31
08
2021
entrez:
15
9
2021
pubmed:
16
9
2021
medline:
16
9
2021
Statut:
epublish
Résumé
Colovesical fistula (CVF) is an abnormal connection between the colon and the urinary bladder. Faecaluria, reported in 40-70% of cases, is virtually pathognomonic for CVF. During the 5th day of recovery in an 84 years old subject, the passage of cloudy, malodorous urine with visible debris was observed. According to the pathognomonic character of faecaluria, the sample was signed to the laboratory for biochemical and microbiological investigation, able to define the type and origin of materials. Following clinical requirements, both biochemical pathways and instrumental procedures able to confirm or exclude the presence of faecal components in urine were considered. No biochemical compound or component addressing faecal compounds in urine results available between laboratory tests. The brown powder component of the pellet was identified as Keratin, with 90% overlapping with the reference spectrum of the compound. FT-IR analysis on urine pellet can be proposed as a simple, non-invasive, and fast method to improve the diagnostic course of CVF.
Identifiants
pubmed: 34522752
doi: 10.1016/j.plabm.2021.e00255
pii: S2352-5517(21)00055-X
pmc: PMC8426557
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e00255Informations de copyright
© 2021 The Authors. Published by Elsevier B.V.
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