Efficacy of fipronil/(S)-methoprene/eprinomectin/praziquantel (Broadline
Animals
Antiparasitic Agents
/ classification
Cat Diseases
/ drug therapy
Cats
/ parasitology
Drug Combinations
Eye
/ parasitology
Female
Inflammation
/ drug therapy
Ivermectin
/ analogs & derivatives
Male
Methoprene
/ therapeutic use
Pets
/ parasitology
Praziquantel
/ therapeutic use
Pyrazoles
/ therapeutic use
Random Allocation
Spirurida Infections
/ drug therapy
Thelazioidea
/ drug effects
Treatment Outcome
Broadline®
Cat
Eprinomectin
Thelazia callipaeda
Journal
Parasites & vectors
ISSN: 1756-3305
Titre abrégé: Parasit Vectors
Pays: England
ID NLM: 101462774
Informations de publication
Date de publication:
15 Sep 2021
15 Sep 2021
Historique:
received:
24
06
2021
accepted:
28
08
2021
entrez:
16
9
2021
pubmed:
17
9
2021
medline:
24
12
2021
Statut:
epublish
Résumé
The present clinical field trial was conducted to assess the efficacy of a broad-spectrum parasiticide spot-on formulation containing eprinomectin (Broadline Fifteen privately owned cats harboring at least one live adult T. callipaeda were included in the study. Cats were randomly allocated to an untreated control group of seven cats or to a Broadline Seven days after treatment, six of eight treated cats were negative for eyeworm infection per visual examination, and on Day 14 no eyeworms were found in the treated cats while the seven untreated cats were still infected (geometric mean: 1.97). All cats had inflammatory ocular signs at inclusion; on Day 14, five of eight treated cats had recovered while all untreated control cats were still symptomatic. All collected parasites were confirmed to be T. callipaeda by morphology and molecular characterization. A single treatment with Broadline
Sections du résumé
BACKGROUND
BACKGROUND
The present clinical field trial was conducted to assess the efficacy of a broad-spectrum parasiticide spot-on formulation containing eprinomectin (Broadline
METHODS
METHODS
Fifteen privately owned cats harboring at least one live adult T. callipaeda were included in the study. Cats were randomly allocated to an untreated control group of seven cats or to a Broadline
RESULTS
RESULTS
Seven days after treatment, six of eight treated cats were negative for eyeworm infection per visual examination, and on Day 14 no eyeworms were found in the treated cats while the seven untreated cats were still infected (geometric mean: 1.97). All cats had inflammatory ocular signs at inclusion; on Day 14, five of eight treated cats had recovered while all untreated control cats were still symptomatic. All collected parasites were confirmed to be T. callipaeda by morphology and molecular characterization.
CONCLUSIONS
CONCLUSIONS
A single treatment with Broadline
Identifiants
pubmed: 34526129
doi: 10.1186/s13071-021-04983-0
pii: 10.1186/s13071-021-04983-0
pmc: PMC8442459
doi:
Substances chimiques
Antiparasitic Agents
0
Drug Combinations
0
Pyrazoles
0
Praziquantel
6490C9U457
Ivermectin
70288-86-7
eprinomectin
75KP30FD8O
Methoprene
8B830OJ2UX
fipronil
QGH063955F
Types de publication
Clinical Trial, Veterinary
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
477Informations de copyright
© 2021. The Author(s).
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