Platelets: a potential role in chronic respiratory diseases?


Journal

European respiratory review : an official journal of the European Respiratory Society
ISSN: 1600-0617
Titre abrégé: Eur Respir Rev
Pays: England
ID NLM: 9111391

Informations de publication

Date de publication:
30 Sep 2021
Historique:
received: 08 03 2021
accepted: 05 06 2021
entrez: 16 9 2021
pubmed: 17 9 2021
medline: 25 11 2021
Statut: epublish

Résumé

Platelets are small anucleate cells known for their role in haemostasis and thrombosis. In recent years, an increasing number of observations have suggested that platelets are also immune cells and key modulators of immunity. They express different receptors and molecules that allow them to respond to pathogens, and to interact with other immune cells. Platelets were linked to the pathogenesis of some inflammatory disorders including respiratory diseases such as asthma and idiopathic pulmonary fibrosis. Here, we discuss the involvement of platelets in different immune responses, and we focus on their potential role in various chronic lung diseases.

Identifiants

pubmed: 34526315
pii: 30/161/210062
doi: 10.1183/16000617.0062-2021
pmc: PMC9488457
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Copyright ©The authors 2021.

Déclaration de conflit d'intérêts

Conflict of interest: M. Chebbo has nothing to disclose. Conflict of interest: C. Duez has nothing to disclose. Conflict of interest: M.C. Alessi has nothing to disclose. Conflict of interest: P. Chanez reports receiving grants or contracts, consulting fees, payment or honoraria for lectures, presentations, speakers’ bureaus, manuscript writing or educational events, support for attending meetings and/or travel fees, in the past 36 months from: ALK, AstraZeneca, Boehringer Ingelheim, Chiesi and Novartis, outside the submitted works. Conflict of interest: D. Gras has nothing to disclose.

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Auteurs

Mohamad Chebbo (M)

Aix-Marseille Univ, INSERM, INRAE, Marseille, France.

Catherine Duez (C)

Aix-Marseille Univ, INSERM, INRAE, Marseille, France.

Marie C Alessi (MC)

Aix-Marseille Univ, INSERM, INRAE, Marseille, France.
APHM, CHU de la Timone, Laboratoire d'hématologie, Marseille, France.

Pascal Chanez (P)

Aix-Marseille Univ, INSERM, INRAE, Marseille, France.
APHM, Hôpital NORD, Clinique des Bronches, Allergie et Sommeil, Marseille, France.

Delphine Gras (D)

Aix-Marseille Univ, INSERM, INRAE, Marseille, France.

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