A household-based community health worker programme for non-communicable disease, malnutrition, tuberculosis, HIV and maternal health: a stepped-wedge cluster randomised controlled trial in Neno District, Malawi.


Journal

BMJ global health
ISSN: 2059-7908
Titre abrégé: BMJ Glob Health
Pays: England
ID NLM: 101685275

Informations de publication

Date de publication:
09 2021
Historique:
received: 05 06 2021
accepted: 27 08 2021
entrez: 16 9 2021
pubmed: 17 9 2021
medline: 13 10 2021
Statut: ppublish

Résumé

Community health worker (CHW) programmes are a valuable component of primary care in resource-poor settings. The evidence supporting their effectiveness generally shows improvements in disease-specific outcomes relative to the absence of a CHW programme. In this study, we evaluated expanding an existing HIV and tuberculosis (TB) disease-specific CHW programme into a polyvalent, household-based model that subsequently included non-communicable diseases (NCDs), malnutrition and TB screening, as well as family planning and antenatal care (ANC). We conducted a stepped-wedge cluster randomised controlled trial in Neno District, Malawi. Six clusters of approximately 20 000 residents were formed from the catchment areas of 11 healthcare facilities. The intervention roll-out was staggered every 3 months over 18 months, with CHWs receiving a 5-day foundational training for their new tasks and assigned 20-40 households for monthly (or more frequent) visits. The intervention resulted in a decrease of approximately 20% in the rate of patients defaulting from chronic NCD care each month (-0.8 percentage points (pp) (95% credible interval: -2.5 to 0.5)) while maintaining the already low default rates for HIV patients (0.0 pp, 95% CI: -0.6 to 0.5). First trimester ANC attendance increased by approximately 30% (6.5pp (-0.3, 15.8)) and paediatric malnutrition case finding declined by 10% (-0.6 per 1000 (95% CI -2.5 to 0.8)). There were no changes in TB programme outcomes, potentially due to data challenges. CHW programmes can be successfully expanded to more comprehensively address health needs in a population, although programmes should be carefully tailored to CHW and health system capacity.

Sections du résumé

BACKGROUND
Community health worker (CHW) programmes are a valuable component of primary care in resource-poor settings. The evidence supporting their effectiveness generally shows improvements in disease-specific outcomes relative to the absence of a CHW programme. In this study, we evaluated expanding an existing HIV and tuberculosis (TB) disease-specific CHW programme into a polyvalent, household-based model that subsequently included non-communicable diseases (NCDs), malnutrition and TB screening, as well as family planning and antenatal care (ANC).
METHODS
We conducted a stepped-wedge cluster randomised controlled trial in Neno District, Malawi. Six clusters of approximately 20 000 residents were formed from the catchment areas of 11 healthcare facilities. The intervention roll-out was staggered every 3 months over 18 months, with CHWs receiving a 5-day foundational training for their new tasks and assigned 20-40 households for monthly (or more frequent) visits.
FINDINGS
The intervention resulted in a decrease of approximately 20% in the rate of patients defaulting from chronic NCD care each month (-0.8 percentage points (pp) (95% credible interval: -2.5 to 0.5)) while maintaining the already low default rates for HIV patients (0.0 pp, 95% CI: -0.6 to 0.5). First trimester ANC attendance increased by approximately 30% (6.5pp (-0.3, 15.8)) and paediatric malnutrition case finding declined by 10% (-0.6 per 1000 (95% CI -2.5 to 0.8)). There were no changes in TB programme outcomes, potentially due to data challenges.
INTERPRETATION
CHW programmes can be successfully expanded to more comprehensively address health needs in a population, although programmes should be carefully tailored to CHW and health system capacity.

Identifiants

pubmed: 34526321
pii: bmjgh-2021-006535
doi: 10.1136/bmjgh-2021-006535
pmc: PMC8444244
pii:
doi:

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

AIMS Public Health. 2017 Nov 30;4(6):590-614
pubmed: 30155504
PLoS One. 2017 Jul 13;12(7):e0180640
pubmed: 28704405
N Engl J Med. 2019 May 23;380(21):1990-1992
pubmed: 31116918
BMJ Open. 2018 Jul 13;8(7):e019473
pubmed: 30007924
Hum Resour Health. 2016 Oct 26;14(1):65
pubmed: 27784298
Health Policy Plan. 2019 Feb 1;34(1):55-66
pubmed: 30668690
Hum Resour Health. 2019 Aug 19;17(1):68
pubmed: 31426801
Glob Heart. 2015 Mar;10(1):39-44
pubmed: 25754565
Hum Resour Health. 2019 Oct 25;17(1):75
pubmed: 31653269
J Glob Health. 2019 Jun;9(1):010808
pubmed: 31275568
BMJ Glob Health. 2018 Jan 12;3(1):e000552
pubmed: 29564158
Bull World Health Organ. 2020 Jan 1;98(1):69-71
pubmed: 31902965
BMC Public Health. 2013 Nov 07;13:1052
pubmed: 24199832
Am J Public Health. 2016 Apr;106(4):e3-e28
pubmed: 26890177
Afr J Prim Health Care Fam Med. 2019 Jul 31;11(1):e1-e7
pubmed: 31368320
PLoS One. 2012;7(8):e42700
pubmed: 22952607
Glob Health Res Policy. 2018 Jun 8;3:17
pubmed: 29930989
Glob Heart. 2017 Sep;12(3):233-243.e6
pubmed: 27993594
Int J Infect Dis. 2019 Dec;89:122-127
pubmed: 31639521
J Acquir Immune Defic Syndr. 2012 Mar 1;59(3):e35-42
pubmed: 22156912
BMJ. 2015 Feb 06;350:h391
pubmed: 25662947
Healthc (Amst). 2015 Dec;3(4):270-6
pubmed: 26699356
Gates Open Res. 2019 Jun 6;3:1468
pubmed: 31294420
Trials. 2017 Mar 4;18(1):101
pubmed: 28259174
Glob Health Sci Pract. 2021 Mar 16;9(Suppl 1):S168-S178
pubmed: 33727328
BMJ Open. 2017 Nov 3;7(11):e015529
pubmed: 29101131
AIDS. 2017 Sep 10;31(14):1999-2006
pubmed: 28692543
BMC Pregnancy Childbirth. 2020 Jan 6;20(1):22
pubmed: 31906939
Stat Med. 2001 Feb 15;20(3):453-72
pubmed: 11180313
Annu Rev Public Health. 2014;35:399-421
pubmed: 24387091
BMJ Glob Health. 2018 Mar 12;3(2):e000634
pubmed: 29607100
BMJ Open. 2020 Oct 21;10(10):e036836
pubmed: 33087368
PLoS One. 2008 May 21;3(5):e2204
pubmed: 18493615

Auteurs

Emily B Wroe (EB)

Partners In Health, Neno, Malawi emwroe@gmail.com.
Division of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.

Basimenye Nhlema (B)

Partners In Health, Neno, Malawi.

Elizabeth L Dunbar (EL)

Partners In Health, Neno, Malawi.
Human Centered Design & Engineering, University of Washington, Seattle, Washington, USA.

Alexandra V Kulinkina (AV)

Partners In Health, Neno, Malawi.
Swiss Tropical and Public Health Institute, Basel, Switzerland.
University of Basel, Basel, Switzerland.

Chiyembekezo Kachimanga (C)

Partners In Health, Neno, Malawi.

Moses Aron (M)

Partners In Health, Neno, Malawi.

Luckson Dullie (L)

Partners In Health, Neno, Malawi.

Henry Makungwa (H)

Partners In Health, Neno, Malawi.

Benson Chabwera (B)

Partners In Health, Neno, Malawi.

Benson Phiri (B)

Partners In Health, Neno, Malawi.

Lawrence Nazimera (L)

Ministry of Health, Neno, Malawi.

Enoch P L Ndarama (EPL)

Ministry of Health, Neno, Malawi.

Annie Michaelis (A)

Partners In Health, Boston, Massachusetts, USA.

Ryan McBain (R)

Partners In Health, Boston, Massachusetts, USA.
RAND, Boston, Massachusetts, USA.

Celia Brown (C)

University of Warwick, Coventry, UK.

Daniel Palazuelos (D)

Division of Global Health Equity, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA, USA.
Partners In Health, Boston, Massachusetts, USA.

Richard Lilford (R)

Institute of Applied Health Research, University of Birmingham, Birmingham, UK.

Samuel I Watson (SI)

Institute of Applied Health Research, University of Birmingham, Birmingham, UK.

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