Undernutrition and Treatment Success in Drug-Resistant Tuberculosis in Uganda.
MDR TB
anaemia
drug resistant
malnutrition
tuberculosis
undernutrition
Journal
Infection and drug resistance
ISSN: 1178-6973
Titre abrégé: Infect Drug Resist
Pays: New Zealand
ID NLM: 101550216
Informations de publication
Date de publication:
2021
2021
Historique:
received:
01
08
2021
accepted:
02
09
2021
entrez:
16
9
2021
pubmed:
17
9
2021
medline:
17
9
2021
Statut:
epublish
Résumé
Undernutrition is associated with unfavourable treatment outcomes among people with drug-resistant tuberculosis (DRTB). Factors influencing the treatment outcomes among undernourished people with DRTB are not well characterised. The aim of this study was to determine factors associated with treatment success among undernourished people with DRTB in Uganda. We analysed data from a retrospective cohort of people with DRTB from 16 treatment sites in Uganda. We included participants with a pre-treatment body mass index (BMI) of <18.5 kilograms/meters Among 473 people with DRTB, 276 (58.4%) were undernourished (BMI < 18.5 Kg/m Most undernourished people with DRTB have severe undernutrition. Smoking and anaemia are modifiable factors which upon appropriate intervention could improve treatment success. The effect of urban residence on the TSR needs to be evaluated further.
Sections du résumé
BACKGROUND
BACKGROUND
Undernutrition is associated with unfavourable treatment outcomes among people with drug-resistant tuberculosis (DRTB). Factors influencing the treatment outcomes among undernourished people with DRTB are not well characterised. The aim of this study was to determine factors associated with treatment success among undernourished people with DRTB in Uganda.
METHODS
METHODS
We analysed data from a retrospective cohort of people with DRTB from 16 treatment sites in Uganda. We included participants with a pre-treatment body mass index (BMI) of <18.5 kilograms/meters
RESULTS
RESULTS
Among 473 people with DRTB, 276 (58.4%) were undernourished (BMI < 18.5 Kg/m
CONCLUSION
CONCLUSIONS
Most undernourished people with DRTB have severe undernutrition. Smoking and anaemia are modifiable factors which upon appropriate intervention could improve treatment success. The effect of urban residence on the TSR needs to be evaluated further.
Identifiants
pubmed: 34526787
doi: 10.2147/IDR.S332148
pii: 332148
pmc: PMC8437412
doi:
Types de publication
Journal Article
Langues
eng
Pagination
3673-3681Informations de copyright
© 2021 Baluku et al.
Déclaration de conflit d'intérêts
The authors declare no competing interests in this work.
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