Updates in Diabetic Wound Healing, Inflammation, and Scarring.

diabetes inflammation scarring wound healing

Journal

Seminars in plastic surgery
ISSN: 1535-2188
Titre abrégé: Semin Plast Surg
Pays: United States
ID NLM: 101131275

Informations de publication

Date de publication:
Aug 2021
Historique:
entrez: 16 9 2021
pubmed: 17 9 2021
medline: 17 9 2021
Statut: ppublish

Résumé

Diabetic patients can sustain wounds either as a sequelae of their disease process or postoperatively. Wound healing is a complex process that proceeds through phases of inflammation, proliferation, and remodeling. Diabetes results in several pathological changes that impair almost all of these healing processes. Diabetic wounds are often characterized by excessive inflammation and reduced angiogenesis. Due to these changes, diabetic patients are at a higher risk for postoperative wound healing complications. There is significant evidence in the literature that diabetic patients are at a higher risk for increased wound infections, wound dehiscence, and pathological scarring. Factors such as nutritional status and glycemic control also significantly influence diabetic wound outcomes. There are a variety of treatments available for addressing diabetic wounds.

Identifiants

pubmed: 34526862
doi: 10.1055/s-0041-1731460
pii: 01305
pmc: PMC8432997
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

153-158

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of Interest None declared.

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Auteurs

Nina Dasari (N)

Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas.

Austin Jiang (A)

Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas.

Anna Skochdopole (A)

Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas.

Jayer Chung (J)

Division of Vascular Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas.

Edward M Reece (EM)

Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas.
Division of Plastic Surgery, Department of Surgery, Texas Children's Hospital, Houston, Texas.

Joshua Vorstenbosch (J)

Division of Plastic Surgery, Department of Surgery, McGill University, Montreal, Canada.

Sebastian Winocour (S)

Division of Plastic Surgery, Department of Surgery, Baylor College of Medicine, Houston, Texas.

Classifications MeSH