Current Concepts in Capsular Contracture: Pathophysiology, Prevention, and Management.

breast implant capsular contracture foreign body reaction inflammation

Journal

Seminars in plastic surgery
ISSN: 1535-2188
Titre abrégé: Semin Plast Surg
Pays: United States
ID NLM: 101131275

Informations de publication

Date de publication:
Aug 2021
Historique:
entrez: 16 9 2021
pubmed: 17 9 2021
medline: 17 9 2021
Statut: ppublish

Résumé

Over 400,000 women in the United States alone will have breast implant surgery each year. Although capsular contracture represents the most common complication of breast implant surgery, surgeons continue to debate the precise etiology. General agreement exists concerning the inflammatory origin of capsular fibrosis, but the inciting events triggering the inflammatory cascade appear to be multifactorial, making it difficult to predict why one patient may develop capsular contracture while another will not. Accordingly, researchers have explored many different surgical, biomaterial, and medical therapies to address these multiple factors in an attempt to prevent and treat capsular contracture. In the current paper, we aim to inform the reader on the most up-to-date understanding of the pathophysiology, prevention, and treatment of capsular contracture.

Identifiants

pubmed: 34526867
doi: 10.1055/s-0041-1731793
pii: 01316
pmc: PMC8432999
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

189-197

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of Interest None declared.

Références

Plast Reconstr Surg. 1992 Aug;90(2):247-54
pubmed: 1631216
Plast Reconstr Surg. 1994 Jan;93(1):123-8; discussion 129-30
pubmed: 8278467
Plast Reconstr Surg Glob Open. 2019 Feb 08;7(2):e2037
pubmed: 30881821
Plast Reconstr Surg. 2020 Nov;146(5):956-962
pubmed: 32852468
Can J Plast Surg. 2008 Winter;16(4):211-5
pubmed: 19949499
Updates Surg. 2020 Jun;72(2):537-546
pubmed: 32062785
Ann Surg Oncol. 2018 Oct;25(10):2899-2908
pubmed: 29978367
Plast Reconstr Surg. 2012 Feb;129(2):327e-337e
pubmed: 22286447
Aesthetic Plast Surg. 2019 Aug;43(4):890-898
pubmed: 31139912
Plast Reconstr Surg. 2018 Jan;141(1):23-30
pubmed: 29280857
Aesthet Surg J. 2021 Jan 25;41(2):189-195
pubmed: 32582953
Sci Am. 2001 Jul;285(1):74-81
pubmed: 11432197
JAMA Surg. 2020 Dec 1;155(12):1132-1140
pubmed: 33026424
Biomaterials. 2003 Mar;24(6):1101-9
pubmed: 12504533
Ann Plast Surg. 2015 Jul;75(1):91-7
pubmed: 26070166
Plast Reconstr Surg. 1986 Jun;77(6):919-32
pubmed: 3520619
Plast Reconstr Surg. 2020 Sep;146(3):516-525
pubmed: 32842102
Plast Reconstr Surg. 2021 Feb 1;147(2):305-315
pubmed: 33177453
Aesthet Surg J. 2021 Jan 1;41(1):34-44
pubmed: 32449906
Aesthet Surg J. 2020 Nov 18;:
pubmed: 33206158
Aesthet Surg J. 2012 Jan;32(1):61-8
pubmed: 22231414
Sci Transl Med. 2020 Apr 15;12(539):
pubmed: 32295900
Biomater Res. 2018 Dec 20;22:37
pubmed: 30598837
Adv Exp Med Biol. 2015;865:109-22
pubmed: 26306446
Aesthet Surg J. 2009 Jan-Feb;29(1):19-25
pubmed: 19233001
Plast Reconstr Surg. 2017 May;139(5):1184e-1194e
pubmed: 28445380
Plast Reconstr Surg. 2010 Dec;126(6):1842-1847
pubmed: 21124125
Clin Plast Surg. 2012 Apr;39(2):127-136
pubmed: 22482354
Aesthetic Plast Surg. 2019 Oct;43(5):1415-1416
pubmed: 31175399
Clin Microbiol Rev. 2002 Apr;15(2):155-66
pubmed: 11932228
Aesthetic Plast Surg. 1992 Spring;16(2):173-9
pubmed: 1570781
Surg Innov. 2017 Oct;24(5):417-422
pubmed: 28681666
Plast Reconstr Surg. 1976 Dec;58(6):689-93
pubmed: 792918
Semin Immunol. 2008 Apr;20(2):86-100
pubmed: 18162407
Aesthetic Plast Surg. 2008 Mar;32(2):303-6
pubmed: 17994260
Plast Reconstr Surg. 2006 Jun;117(7):2182-90
pubmed: 16772915
J Plast Reconstr Aesthet Surg. 2019 Dec;72(12):1986-1995
pubmed: 31653596
J Long Term Eff Med Implants. 1995;5(1):11-8
pubmed: 10163505
Aesthetic Plast Surg. 2021 Feb;45(1):51-60
pubmed: 32860077
Aesthetic Plast Surg. 2016 Aug;40(4):613-24
pubmed: 27302415
J Autoimmun. 2004 Aug;23(1):81-91
pubmed: 15236756
Plast Reconstr Surg Glob Open. 2019 May 17;7(5):e2213
pubmed: 31333946
J Biomed Mater Res A. 2017 Mar;105(3):927-940
pubmed: 27813288
Aesthetic Plast Surg. 2019 Apr;43(2):336-347
pubmed: 30542977
Ann Plast Surg. 2013 Jan;70(1):16-22
pubmed: 21712700
Plast Reconstr Surg. 2015 Nov;136(5):592e-596e
pubmed: 26505715
Scand J Plast Reconstr Surg Hand Surg. 1989;23(3):223-9
pubmed: 2617224
Plast Reconstr Surg. 2014 Feb;133(2):214-221
pubmed: 24469157
Arch Plast Surg. 2018 Mar;45(2):177-179
pubmed: 29506340
J Plast Reconstr Aesthet Surg. 2014 Mar;67(3):308-15
pubmed: 24389289
Plast Reconstr Surg. 2016 Aug;138(2):329-337
pubmed: 27064232
Ann Plast Surg. 2016 May;76(5):485-8
pubmed: 27070347
Clin Transl Med. 2014 Dec;3(1):62
pubmed: 26932379
Emerg Infect Dis. 2002 Sep;8(9):881-90
pubmed: 12194761
Aesthetic Plast Surg. 2018 Dec;42(6):1485-1491
pubmed: 30187083
J Plast Reconstr Aesthet Surg. 2013 Sep;66(9):1165-72
pubmed: 23664574
Eplasty. 2017 Dec 21;17:e41
pubmed: 29348783
Sci Rep. 2020 Jan 24;10(1):1137
pubmed: 31980737
Plast Reconstr Surg. 2020 Apr;145(4):686e-696e
pubmed: 32221195
Ann Plast Surg. 2006 Sep;57(3):248-51
pubmed: 16929187
Ann Plast Surg. 2013 Apr;70(4):447-53
pubmed: 23486129
Aesthet Surg J. 2012 Nov;32(8):956-63
pubmed: 22964141
Plast Reconstr Surg. 1995 Oct;96(5):1119-23; discussion 1124
pubmed: 7568488
Aesthetic Plast Surg. 2021 Jun;45(3):1273-1281
pubmed: 32968820
Ann Plast Surg. 1987 Dec;19(6):512-4
pubmed: 3439764
Plast Reconstr Surg Glob Open. 2013 Nov 07;1(7):e55
pubmed: 25289250
Aesthet Surg J. 2019 Jan 31;39(Suppl_1):S36-S48
pubmed: 30715176
Arch Plast Surg. 2015 Sep;42(5):532-43
pubmed: 26430623
Plast Reconstr Surg Glob Open. 2019 Oct 15;7(10):e2466
pubmed: 31772893
Aesthetic Plast Surg. 2019 Aug;43(4):918-926
pubmed: 31049639
Aesthet Surg J. 2018 Feb 15;38(3):276-278
pubmed: 29267945
Plast Reconstr Surg. 2012 Nov;130(5):1141-1146
pubmed: 23096614
Aesthetic Plast Surg. 2020 Jun;44(3):735-742
pubmed: 31919627
Plast Reconstr Surg. 2012 Oct;130(4):793-800
pubmed: 22691845
Plast Reconstr Surg Glob Open. 2016 Oct 4;4(10):e1096
pubmed: 27826488
Plast Reconstr Surg. 2017 Sep;140(3):427-431
pubmed: 28841597
J Plast Reconstr Aesthet Surg. 2019 Jul;72(7):1051-1059
pubmed: 31076195
Plast Reconstr Surg. 2006 Oct;118(5):1224-1236
pubmed: 17016195
Plast Reconstr Surg. 2016 Mar;137(3):826-841
pubmed: 26910663
Aesthet Surg J. 2021 Jan 29;:
pubmed: 33512424
Plast Reconstr Surg. 2010 Sep;126(3):835-842
pubmed: 20811216
Dermatol Ther (Heidelb). 2016 Jun;6(2):185-206
pubmed: 27250839
Aesthetic Plast Surg. 2019 Aug;43(4):910-917
pubmed: 30937475
J Plast Reconstr Aesthet Surg. 2018 Sep;71(9):e29-e48
pubmed: 29980456
Plast Reconstr Surg. 2020 Nov;146(5):1029-1041
pubmed: 33141530
Plast Reconstr Surg. 2020 Mar;145(3):701-710
pubmed: 32097310
Aesthet Surg J. 2016 May;36(5):550-6
pubmed: 26672104

Auteurs

Tyler Safran (T)

Division of Plastic Surgery, McGill University, Montreal, Quebec, Canada.

Hillary Nepon (H)

Division of Experimental Surgery, McGill University, Montreal, Quebec, Canada.

Carrie K Chu (CK)

Department of Plastic Surgery, MD Anderson Cancer Center, Houston, Texas.

Sebastian Winocour (S)

Division of Plastic Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas.

Amanda M Murphy (AM)

Division of Plastic Surgery, McGill University, Montreal, Quebec, Canada.

Peter G Davison (PG)

Division of Plastic Surgery, McGill University, Montreal, Quebec, Canada.

Tassos Dionisopolos (T)

Division of Plastic Surgery, McGill University, Montreal, Quebec, Canada.

Joshua Vorstenbosch (J)

Division of Plastic Surgery, McGill University, Montreal, Quebec, Canada.

Classifications MeSH