[Bilateral orbital myeloid sarcoma: the circumstance of the discovery of acute myeloid leukemia (a case report)].
Sarcome myéloïde orbitaire bilatérale: circonstance de découverte d´une leucémie aiguë myéloïde (à propos d´un cas).
Madagascar
Myeloid sarcoma
case report
exophthalmos
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2021
2021
Historique:
received:
28
07
2020
accepted:
18
06
2021
entrez:
16
9
2021
pubmed:
17
9
2021
medline:
7
10
2021
Statut:
epublish
Résumé
Myeloid sarcoma is a rare ocular manifestation of acute myeloid leukemia. Bilateral manifestation preceding any clinical signs of leukemia is even rarer. We here report the case of a 16-month-old patient with rapidly progressive, inflammatory, acute bilateral exophthalmos associated with exposure keratitis. Computed tomography (CT) scan of the orbit and of the brain showed bilateral tissue-like infiltration into the orbital cavity. Blood tests showed biologic inflammatory syndrome, bicytopenia and circulating blasts 83%. Myelogram was performed based on the presence of circulating blasts; it showed acute myeloid leukemia (grade 4). Clinicians should suspect myeloid sarcoma in patients with bilateral exophthalmos and conduct a careful interpretation of blood test results.
Identifiants
pubmed: 34527161
doi: 10.11604/pamj.2021.39.145.25242
pii: PAMJ-39-145
pmc: PMC8418160
doi:
Types de publication
Case Reports
Langues
fre
Sous-ensembles de citation
IM
Pagination
145Informations de copyright
Copyright: Rado Rambeloson et al.
Déclaration de conflit d'intérêts
Les auteurs ne déclarent aucun conflit d’intérêts.
Références
J Fr Ophtalmol. 2002 Jan;25(1):62-6
pubmed: 11965121
Orbit. 2015;34(5):248-52
pubmed: 26186043
Cancer. 2008 Jan 15;112(2):416-32
pubmed: 18074355
J Hematol Oncol. 2009 Jan 24;2:4
pubmed: 19166619
Ther Adv Hematol. 2011 Oct;2(5):309-16
pubmed: 23556098
J Med Case Rep. 2016 Feb 04;10:31
pubmed: 26846095
Am J Ophthalmol. 1975 Dec;80(6):975-90
pubmed: 1060381
Arch Ophthalmol. 1989 May;107(5):697-700
pubmed: 2719579
Cancer Radiother. 2016 Feb;20(1):60-5
pubmed: 26775223