Assessment of ganglion cell complex, macular thickness, and optic disc parameters in keratoconus patients.

Ganglion cell complex Keratoconus Macular thickness Optic coherence tomography Retinal nerve fiber layer

Journal

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
ISSN: 1319-4534
Titre abrégé: Saudi J Ophthalmol
Pays: India
ID NLM: 9425601

Informations de publication

Date de publication:
Historique:
received: 01 01 2019
revised: 22 05 2019
accepted: 06 07 2020
entrez: 16 9 2021
pubmed: 17 9 2021
medline: 17 9 2021
Statut: epublish

Résumé

Keratoconus (KC) is bilateral noninflammatory corneal disorder characterized by progressive corneal thinning, protrusion, and scarring. The purpose of this study was to evaluate ganglion cell complex(GCC), macula thickness(MT) and optic head disc parameters in keratoconus patients. A hospital based prospective clinical case series was performed in Inonu University School of Medicine. 52 eyes of 52 keratoconus patients and 50 eyes of 50 normal patients were enrolled. There is no statistically significant in MT between groups. GCC in nasal superior, temporal superior and temporal inferior 9 mm from macula were found statistically significant decrease in keratoconus group (p<0,05). In optic disc analysis fifth and the eleventh clock-hour quadrants of peripapiller retina nerve fiber layer and cup area ratio were found statistically significant decrease in keratoconic eyes (p<0,05). We thought that structural retinal changes seem in keratoconus eyes; keratoconus pathogenesis may affect not only cornea but also retina and optic nerve head.

Identifiants

pubmed: 34527868
doi: 10.4103/1319-4534.322604
pii: SJO-34-256
pmc: PMC8409350
doi:

Types de publication

Journal Article

Langues

eng

Pagination

256-260

Informations de copyright

Copyright: © 2021 Saudi Journal of Ophthalmology.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

Références

Invest Ophthalmol Vis Sci. 2004 Jul;45(7):2224-30
pubmed: 15223799
Am J Ophthalmol. 2000 May;129(5):667-8
pubmed: 10844063
Br J Ophthalmol. 2009 Jun;93(6):820-4
pubmed: 19304583
J Med Case Rep. 2010 Feb 19;4:58
pubmed: 20170483
Br J Ophthalmol. 2012 Jan;96(1):57-61
pubmed: 21349942
Invest Ophthalmol Vis Sci. 2010 Sep;51(9):4471-5
pubmed: 20445116
Cornea. 2011 Dec;30(12):1318-21
pubmed: 22001816
JAMA Neurol. 2013 Jan;70(1):34-43
pubmed: 23318513
Retina. 2008 Jan;28(1):94-6
pubmed: 18185144
Surv Ophthalmol. 1984 Jan-Feb;28(4):293-322
pubmed: 6230745
Clin Exp Optom. 2015 Jul;98(4):319-22
pubmed: 26104591
Graefes Arch Clin Exp Ophthalmol. 2012 Feb;250(2):247-54
pubmed: 21861085
Mult Scler. 2019 Feb;25(2):196-203
pubmed: 29095097
Cornea. 2002 Apr;21(3):331-2
pubmed: 11917188
J Ophthalmol. 2015;2015:245953
pubmed: 26064670
Ann Ophthalmol. 1971 Jun;3(6):664-5 p
pubmed: 5164435
Ophthalmic Surg Lasers Imaging. 2012 Sep-Oct;43(5):401-7
pubmed: 22692640
PLoS One. 2011 Jan 27;6(1):e16437
pubmed: 21298010
Surv Ophthalmol. 1998 Jan-Feb;42(4):297-319
pubmed: 9493273
Semin Ophthalmol. 2017;32(6):676-681
pubmed: 27366960
Ophthalmologica. 2013;229(4):203-7
pubmed: 23635553

Auteurs

Gözde Orman (G)

Department of Opthalmology, Ankara Training and Research Hospital, Ankara, Turkey.

Penpe Gul Fırat (PG)

Department of Ophthalmology, Inonu University School of Medicine, Malatya, Turkey.

Selim Doganay (S)

Department of Ophthalmology, Uludag University School of Medicine, Bursa, Turkey.

Derya Doganay (D)

Department of Ophthalmology, Cekirge State Hospital, Bursa, Turkey.

Classifications MeSH