Staphylococcus aureus Multidrug Resistance-Associated Proteins Anti-Bacterial Agents / chemistry Norfloxacin / pharmacology Bacterial Proteins / chemistry Microbial Sensitivity Tests
antibacterial activity efflux pump molecular docking α β-amyrin mixture

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
2022
Historique:
pubmed: 17 9 2021
medline: 28 12 2022
entrez: 16 9 2021
Statut: ppublish

Résumé

The use of the bacterial efflux pump mechanism to reduce the concentrations of antibiotics in the intracellular to the extracellular region is one of the main mechanisms by which bacteria acquire resistance to antibiotics. The present study aims to evaluate the antibacterial activity of the α,β-amyrin mixture isolated from

Identifiants

DOI: 10.1080/07391102.2021.1976277 PMID: 34528866
pubmed: 34528866
doi: 10.1080/07391102.2021.1976277
doi:

Substances chimiques

beta-amyrin KM8353IPSO
Multidrug Resistance-Associated Proteins 0
Anti-Bacterial Agents 0
Norfloxacin N0F8P22L1P
Bacterial Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

12785-12799

Auteurs

Raíssa C Oliveira (RC)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
ORCID: 0000-0001-7513-5493

Paulo N Bandeira (PN)

Science and Technology Centre, Course of Chemistry, State University Vale do Acaraú, Sobral, CE, Brazil.
ORCID: 0000-0001-5374-1839

Telma L G Lemos (TLG)

Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, CE, Brazil.
ORCID: 0000-0002-7031-860X

Hélcio S Dos Santos (HS)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
Science and Technology Centre, Course of Chemistry, State University Vale do Acaraú, Sobral, CE, Brazil.
ORCID: 0000-0001-5527-164X

Jackelyne R Scherf (JR)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
ORCID: 0000-0002-1738-005X

Janaina E Rocha (JE)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
ORCID: 0000-0001-7680-0651

Raimundo L S Pereira (RLS)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
ORCID: 0000-0001-8205-7120

Thiago S Freitas (TS)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
ORCID: 0000-0002-0917-4715

Priscila R Freitas (PR)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
ORCID: 0000-0003-4047-4836

Francisco N Pereira-Junior (FN)

Center of Agricultural Sciences and of the Biodiversity, Federal University of Cariri, Juazeiro do Norte, CE, Brazil.
ORCID: 0000-0002-6356-989X

Márcia M Marinho (MM)

Faculty of Education, Sciences and Letters of Iguatu, State University of Ceará, Campus FECLI, Iguatu, CE, Brazil.
ORCID: 0000-0002-7640-2220

Emanuelle M Marinho (EM)

Department of Analytical Chemistry and Physical Chemistry, Federal University of Ceará, Fortaleza, CE, Brazil.
ORCID: 0000-0003-1548-8574

Emmanuel S Marinho (ES)

Group of Theoretical Chemistry and Electrochemistry, State University of Ceará, Campus FAFIDAM, Limoeiro do Norte, CE, Brazil.
ORCID: 0000-0002-4774-8775

Carlos E S Nogueira (CES)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
Department of Physics, Regional University of Cariri, Juazeiro do Norte, CE, Brazil.
ORCID: 0000-0002-3554-3780

Henrique D M Coutinho (HDM)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
ORCID: 0000-0002-6634-4207

Alexandre M R Teixeira (AMR)

Graduate Program in Biological Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, CE, Brazil.
Department of Physics, Regional University of Cariri, Juazeiro do Norte, CE, Brazil.
ORCID: 0000-0001-6786-2076

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Classifications MeSH

questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Cocci à Gram positif › Staphylococcaceae › Staphylococcus › Staphylococcus aureus ›
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs d'anions › Transporteurs d'anions organiques › Transporteurs d'anions organiques ATP-dépendants › Protéines associées à la multirésistance aux médicaments ›
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens ›
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Quinolinone › Fluoroquinolones › Norfloxacine ›
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes ›
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne ›