The Role of Biofilms in Chronic Otitis Media-Active Squamosal Disease: An Evaluative Study.
Journal
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
ISSN: 1537-4505
Titre abrégé: Otol Neurotol
Pays: United States
ID NLM: 100961504
Informations de publication
Date de publication:
01 10 2021
01 10 2021
Historique:
entrez:
16
9
2021
pubmed:
17
9
2021
medline:
8
10
2021
Statut:
ppublish
Résumé
To study the presence of biofilms in patients of chronic otitis media (COM)-active squamosal disease and to evaluate the microflora and clinical impact of biofilms. A total of 35 patients suffering from COM - active squamosal disease was studied. Cholesteatoma sample was collected at the time of mastoid surgery and the same was used to image for biofilms by scanning electron microscope. The said sample was also analyzed microbiologically. Biofilms were present in 25 (72%) patients including 6 cases of fungal biofilms (24%). Biofilms were detected irrespective of the micro-organism growth. No statistically significant relationship was observed between biofilms and discharging ear and complications of COM. Though univariate analysis of our data found some correlation between duration of disease, the extent of cholesteatoma and ossicular necrosis but multivariate analysis revealed no such associations, thereby implying a doubtful association between these factors and biofilm. Biofilms are an integral part of cholesteatoma ear disease and sometimes harbors fungal isolates.
Identifiants
pubmed: 34528922
doi: 10.1097/MAO.0000000000003259
pii: 00129492-202110000-00025
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1279-e1285Informations de copyright
Copyright © 2021, Otology & Neurotology, Inc.
Déclaration de conflit d'intérêts
This study has no financial conflict of interest. Done in a Central Government Medical College (Tertiary Care Teaching Hospital). None of the authors has any conflict of interest, financial, or otherwise. All the doctors in this study are employed by the “Government of India” and paid salary by the Government of India, and the medical college is a “Central Government Institution.”
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