Diagnostic Laboratories' Capacities and Preparedness for Emerging Viral Diseases in Guinea and Mali.

Diagnostic Emerging Viral Diseases Guinea Mali Preparedness

Journal

Infectious diseases diagnosis & treatment
ISSN: 2577-1515
Titre abrégé: Infect Dis Diagn Treat
Pays: United States
ID NLM: 101763328

Informations de publication

Date de publication:
2020
Historique:
entrez: 17 9 2021
pubmed: 1 1 2020
medline: 1 1 2020
Statut: ppublish

Résumé

The 2014-2016 Ebola epidemic in Guinea highlighted the need for more extensive evaluation of laboratories diagnostic capacities and preparedness in anticipation of future emerging viral disease outbreaks. We developed a questionnaire to assess the diagnostic capacities and preparedness of the four major medical laboratories in Guinea and Mali that are responsible for the provision of Ebola, Lassa, and Dengue diagnostics. The questionnaire inquired about the current state and need for equipment and reagents and adequacy of equipment and training received. In Guinea, all three diagnostic laboratories have the capacity and are well-prepared to perform Ebola diagnostics, however, only two have the capacity and trained staff to diagnose Lassa and none are currently prepared to diagnose Dengue infection. In Mali, the University Clinical Research Center (UCRC) laboratory, which was in charge of Ebola diagnostics during the last epidemic, currently has the capacity and is prepared to diagnose Ebola, Lassa, and Dengue infections. Combined, Guinea and Mali appear to have complementary capacity and preparedness to diagnose these Category A Priority Pathogens. While, the equipment, reagents and training efforts should be maintained, the gap in Dengue diagnostic capability in Guinea should be addressed with further equipping and training of additional district laboratories to strengthen the public health response for all viral diseases in these high-risk, yet, low-resource settings.

Identifiants

pubmed: 34532653
pmc: PMC8442766
mid: NIHMS1585957
pii:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : FIC NIH HHS
ID : D43 TW010350
Pays : United States
Organisme : FIC NIH HHS
ID : D71 TW010428
Pays : United States

Références

J Infect Dis. 2016 Oct 15;214(suppl 3):S164-S168
pubmed: 27707892
MMWR Suppl. 2016 Jul 08;65(3):4-11
pubmed: 27389903
Emerg Infect Dis. 2011 Aug;17(8):1349-54
pubmed: 21801609
Biosens Bioelectron. 2016 Jan 15;75:254-72
pubmed: 26319169
Viral Immunol. 2008 Jun;21(2):123-32
pubmed: 18476771
J Clin Microbiol. 2000 Jul;38(7):2670-7
pubmed: 10878062
PLoS Negl Trop Dis. 2009;3(3):e388
pubmed: 19255625
BMC Infect Dis. 2012 Sep 28;12:233
pubmed: 23020074
Pathog Glob Health. 2016 Jun-Jul;110(4-5):137-47
pubmed: 27315342
BMC Infect Dis. 2015 May 29;15:217
pubmed: 26022703
Infect Dis Ther. 2015 Dec;4(4):365-90
pubmed: 26363787
Clin Trials. 2016 Feb;13(1):73-8
pubmed: 26768557
J Clin Microbiol. 2010 Jun;48(6):2009-13
pubmed: 20351210
Curr Opin Virol. 2019 Aug;37:132-138
pubmed: 31518896
J Infect Dis. 2016 Oct 15;214(suppl 3):S169-S176
pubmed: 27333914
J Infect Dis. 2016 Oct 15;214(suppl 3):S203-S209
pubmed: 27521365
PLoS Negl Trop Dis. 2015 Mar 17;9(3):e0003631
pubmed: 25781465
J Clin Microbiol. 2001 Sep;39(9):3267-71
pubmed: 11526161

Auteurs

Tiffany Zhang Teng (TZ)

Institute for Global Health, Northwestern University, Chicago, Illinois, USA.

Abdoul Habib Beavogui (AH)

Centre National de Formation et de Recherche en Santé Rurale de Maferinyah, Forécariah, Guinea.
African Center of Excellence for Prevention and Control of Transmissible Diseases (CEA-PCMT), Gamal Abdel Nasser University of Conakry, Conakry, Guinea.

Bassirou Diarra (B)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Alexandre Delamou (A)

Centre National de Formation et de Recherche en Santé Rurale de Maferinyah, Forécariah, Guinea.
African Center of Excellence for Prevention and Control of Transmissible Diseases (CEA-PCMT), Gamal Abdel Nasser University of Conakry, Conakry, Guinea.

Jane Holl (J)

Center for Healthcare Delivery Science and Innovation, The University of Chicago, Chicago, Illinois, USA.

Almoustapha Issiaka Maiga (AI)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Yeya Dit Sadio Sarro (YD)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Amadou Kone (A)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Bourahima Kone (B)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Djeneba Bocar Fofana (DB)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Etienne Dembele (E)

Institute for Global Health, Northwestern University, Chicago, Illinois, USA.

Mamadou Saliou Sow (MS)

Centre de Recherche et de Formation en Infectiologie de Guinée, University of Conakry, Conakry, Guinea.

Moussa Seydi (M)

Université Cheikh Anta Diop, Dakar, Sénégal.

Aboubacar Alassane Oumar (AA)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Mahamadou Diakité (M)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Souleymane Diallo (S)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Seydou Doumbia (S)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Sounkalo Dao (S)

University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Robert L Murphy (RL)

Institute for Global Health, Northwestern University, Chicago, Illinois, USA.

Mamoudou Maiga (M)

Institute for Global Health, Northwestern University, Chicago, Illinois, USA.
University Clinical Research Center (UCRC)-SEREFO, University of Sciences, Techniques and Technologies of Bamako (USTTB), Bamako, Mali.

Classifications MeSH