Identification of novel potential inhibitors of varicella-zoster virus thymidine kinase from ethnopharmacologic relevant plants through an

Humans Antiviral Agents / pharmacology Chickenpox / drug therapy Herpes Zoster / drug therapy Herpesvirus 3, Human / drug effects Thymidine Kinase / antagonists & inhibitors Ethnopharmacology Phytochemicals / pharmacology
Chickenpox molecular docking molecular dynamics simulations thymidine kinase varicella zoster virus

Journal

Journal of biomolecular structure & dynamics
ISSN: 1538-0254
Titre abrégé: J Biomol Struct Dyn
Pays: England
ID NLM: 8404176

Informations de publication

Date de publication:
2022
Historique:
pubmed: 18 9 2021
medline: 28 12 2022
entrez: 17 9 2021
Statut: ppublish

Résumé

Although Varicella or chickenpox infection which is caused by the varicella-zoster virus (VZV) has significantly been managed through vaccination, it remains an infection that poses threats to the nearest future due to therapeutic drawbacks. The focus of this research was geared towards

Identifiants

DOI: 10.1080/07391102.2021.1977700 PMID: 34533095
pubmed: 34533095
doi: 10.1080/07391102.2021.1977700
doi:

Substances chimiques

Antiviral Agents 0
Thymidine Kinase EC 2.7.1.21
Phytochemicals 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

12932-12947

Auteurs

Samuel Kojo Kwofie (SK)

Department of Biomedical Engineering, School of Engineering Sciences, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana.
West African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana.
ORCID: 0000-0002-1093-1517

Dorothy Gyamfua Annan (DG)

West African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana.

Cynthia Ayefoumi Adinortey (CA)

Department of Molecular Biology and Biotechnology, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
ORCID: 0000-0001-8569-8433

Daniel Boison (D)

Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
ORCID: 0000-0002-2242-7502

Gabriel Brako Kwarko (GB)

West African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana.

Rachel Araba Abban (RA)

West African Centre for Cell Biology of Infectious Pathogens, Department of Biochemistry, Cell and Molecular Biology, College of Basic and Applied Sciences, University of Ghana, Accra, Ghana.

Michael Buenor Adinortey (MB)

Department of Biochemistry, School of Biological Sciences, University of Cape Coast, Cape Coast, Ghana.
ORCID: 0000-0001-8287-7460

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Identification of novel potential inhibitors...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiviraux › Identification of novel potential inhibitors...
questionsmedicales.fr › Infection › Maladies virales › Infections à virus à ADN › Infections à Herpesviridae › Infection à virus varicelle-zona › Varicelle › Identification of novel potential inhibitors...
questionsmedicales.fr › Infection › Maladies virales › Infections à virus à ADN › Infections à Herpesviridae › Infection à virus varicelle-zona › Zona › Identification of novel potential inhibitors...
questionsmedicales.fr › Virus › Virus à ADN › Herpesviridae › Alphaherpesvirinae › Varicellovirus › Herpèsvirus humain de type 3 › Identification of novel potential inhibitors...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Phosphotransferases › Phosphotransferases (Alcohol Group Acceptor) › Thymidine kinase › Identification of novel potential inhibitors...
questionsmedicales.fr › Sciences sociales › Anthropologie › Anthropologie culturelle › Médecine traditionnelle › Ethnopharmacologie › Identification of novel potential inhibitors...
questionsmedicales.fr › Facteurs biologiques › Composés phytochimiques › Identification of novel potential inhibitors...