Reverse remodeling of tricuspid valve morphology and function in chronic thromboembolic pulmonary hypertension patients following pulmonary thromboendarterectomy: a cardiac magnetic resonance imaging and invasive hemodynamic study.
Aged
Cardiac Catheterization
Case-Control Studies
Chronic Disease
Echocardiography, Doppler, Color
Endarterectomy
/ adverse effects
Female
Hemodynamics
Humans
Hypertension, Pulmonary
/ diagnostic imaging
Magnetic Resonance Imaging, Cine
Male
Middle Aged
Predictive Value of Tests
Pulmonary Artery
/ diagnostic imaging
Recovery of Function
Thromboembolism
/ diagnostic imaging
Time Factors
Treatment Outcome
Tricuspid Valve
/ diagnostic imaging
Cardiac magnetic resonance imaging
Chronic thromboembolic pulmonary hypertension
Tricuspid valve
Journal
BMC cardiovascular disorders
ISSN: 1471-2261
Titre abrégé: BMC Cardiovasc Disord
Pays: England
ID NLM: 100968539
Informations de publication
Date de publication:
17 09 2021
17 09 2021
Historique:
received:
05
07
2021
accepted:
08
09
2021
entrez:
18
9
2021
pubmed:
19
9
2021
medline:
18
1
2022
Statut:
epublish
Résumé
To investigate changes in tricuspid annulus (TA) and tricuspid valve (TV) morphology among chronic thromboembolic pulmonary hypertension (CTEPH) patients before and 12 months after pulmonary thromboendarterectomy (PEA) and compare these findings to normal control subjects. 20 CTEPH patients and 20 controls were enrolled in the study. The patients were examined with echocardiography, right heart catherization and cardiac magnetic resonance imaging prior to PEA and 12 months after. Right atrium (RA) volume was significantly reduced from baseline to 12 months after PEA (30 ± 9 vs 23 ± 5 ml/m In CTEPH patients selected for PEA, TV tenting height, volume and valve area are significantly increased whereas annulus size and shape are less affected. The alterations in TV morphology are fully reversed after PEA and correlates to improvements of right ventricular-pulmonary arterial coupling.
Sections du résumé
BACKGROUND
To investigate changes in tricuspid annulus (TA) and tricuspid valve (TV) morphology among chronic thromboembolic pulmonary hypertension (CTEPH) patients before and 12 months after pulmonary thromboendarterectomy (PEA) and compare these findings to normal control subjects.
METHODS
20 CTEPH patients and 20 controls were enrolled in the study. The patients were examined with echocardiography, right heart catherization and cardiac magnetic resonance imaging prior to PEA and 12 months after.
RESULTS
Right atrium (RA) volume was significantly reduced from baseline to 12 months after PEA (30 ± 9 vs 23 ± 5 ml/m
CONCLUSION
In CTEPH patients selected for PEA, TV tenting height, volume and valve area are significantly increased whereas annulus size and shape are less affected. The alterations in TV morphology are fully reversed after PEA and correlates to improvements of right ventricular-pulmonary arterial coupling.
Identifiants
pubmed: 34535073
doi: 10.1186/s12872-021-02248-3
pii: 10.1186/s12872-021-02248-3
pmc: PMC8447771
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
450Informations de copyright
© 2021. The Author(s).
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