Excising or preserving perforation margins in endoscopic transtympanic cartilage myringoplasty does not affect surgical success.
cartilage myringoplasty
chronic otitis media
chronic tympanic membrane perforation
mucoepithelial junction
neovascularisation
perforation margin
Journal
Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
ISSN: 1749-4486
Titre abrégé: Clin Otolaryngol
Pays: England
ID NLM: 101247023
Informations de publication
Date de publication:
01 2022
01 2022
Historique:
revised:
27
07
2021
received:
05
03
2021
accepted:
05
09
2021
pubmed:
19
9
2021
medline:
1
3
2022
entrez:
18
9
2021
Statut:
ppublish
Résumé
To compare the outcome of endoscopic transtympanic cartilage myringoplasty with and without removal of perforation edges for repairing chronic perforations with mucosal chronic otitis media (COM). Quasi-randomised clinical trial. Tertiary referral centre. Patients with chronic perforations and mucosal COM undergoing endoscopic transtympanic cartilage myringoplasty were allocated to a control group for whom the perforation edges were preserved (n = 40) and an intervention group for whom the edges were removed (n = 39). Mean operation time, graft success rate, mean scores of graft neovascularisation and epithelialisation, and hearing were compared between the groups at 4 weeks and/or 6 months postoperatively. Graft success rate was 95% (38/40) in the control group and 97% (38/39) in the intervention group at 6 months postoperatively; the difference was not significant. Mean graft neovascularisation scores 4 weeks postoperatively were 2.52 ± 0.59 in the control group and 2.58 ± 0.55 in the intervention group; the difference was not significant. Mean graft epithelisation scores 4 weeks postoperatively were 1.48 ± 0.57 in the control group and 1.68 ± 0.51 in the intervention group; the difference was not significant and remained nonsignificant 6 months postoperatively (2.5 ± 0.55 vs. 2.76 ± 0.36). Audiological outcomes at 6 months did not differ between the groups. Endoscopic, transtympanic cartilage underlay myringoplasty with preservation of the perforation margins did not affect graft neovascularisation, epithelialisation or success. Longer-term outcomes and risk of cholesteatoma require further study.
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
94-99Subventions
Organisme : Health Commission of Zhejiang province, China
ID : 2021KY1186
Organisme : The Science and Technology Agency of Yiwu city, China
ID : (Grants#2018-3-76)
Informations de copyright
© 2021 John Wiley & Sons Ltd.
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