Acute kidney injury is a common and significant complication following ileostomy formation.


Journal

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
ISSN: 1463-1318
Titre abrégé: Colorectal Dis
Pays: England
ID NLM: 100883611

Informations de publication

Date de publication:
01 2022
Historique:
revised: 21 07 2021
received: 25 04 2021
accepted: 09 09 2021
pubmed: 19 9 2021
medline: 31 3 2022
entrez: 18 9 2021
Statut: ppublish

Résumé

The aim was to characterize the incidence and short-term prognostic value of an acute kidney injury (AKI) during the admission where an ileostomy is formed. Adults with a baseline serum creatinine measurement discharged alive after ileostomy formation from 2014 to 2016 were included. All patients had daily basic metabolic panels and the Kidney Diseases Improving Global Outcomes criteria were used to determine the presence and severity of any AKI. Dehydration was defined by a single urine abnormality or clinical criteria combined with an objective abnormality in vitals or basic metabolic panels. Of 262 patients, 19.4% sustained an AKI (74.5% Stage I, 15.7% Stage II, 9.8% Stage III) during the index admission. Predictors of incident AKI were increasing age, male sex, higher baseline creatinine and open surgery. Patients with AKI had significantly longer length of stay and 45% had creatinine <1.0 mg/dl at discharge. Of the total cohort, 11% were readmitted with dehydration and the independent predictors were AKI during the index admission, high ileostomy output, age >65 years, male sex and prior ileostomy. Of those readmitted with dehydration, 79% had AKI at readmission. Nearly 20% of patients with ileostomies develop an AKI during the index admission with almost half resolving by discharge. Patients with AKIs are at high risk for 30-day dehydration-related readmission and AKI is present in nearly 80% of those readmitted with dehydration. Since AKI is objective, based on routine laboratory measures, and has known prognostic value it is probably a more robust outcome than dehydration for researchers, surgeons and patients.

Identifiants

pubmed: 34536959
doi: 10.1111/codi.15917
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

102-110

Informations de copyright

© 2021 Association of Coloproctology of Great Britain and Ireland.

Références

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Auteurs

Anthony Loria (A)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

Alexa Melucci (A)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

Jenny Speranza (J)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

Christina Cellini (C)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

Rabih Salloum (R)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

Larissa K Temple (LK)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

Fergal J Fleming (FJ)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

Carla F Justiniano (CF)

Department of Surgery, University of Rochester Medical Center, Rochester, New York, USA.

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