General estimates of the energy cost of walking in people with different levels and causes of lower-limb amputation: a systematic review and meta-analysis.


Journal

Prosthetics and orthotics international
ISSN: 1746-1553
Titre abrégé: Prosthet Orthot Int
Pays: France
ID NLM: 7707720

Informations de publication

Date de publication:
01 Oct 2021
Historique:
received: 12 01 2021
accepted: 27 07 2021
pubmed: 21 9 2021
medline: 29 10 2021
entrez: 20 9 2021
Statut: ppublish

Résumé

Energy cost of walking (ECw) is an important determinant of walking ability in people with a lower-limb amputation. Large variety in estimates of ECw has been reported, likely because of the heterogeneity of this population in terms of level and cause of amputation and walking speed. To assess (1) differences in ECw between people with and without a lower-limb amputation, and between people with different levels and causes of amputation, and (2) the association between ECw and walking speed. Systematic review and meta-analysis. We included studies that compared ECw in people with and without a lower-limb amputation. A meta-analysis was done to compare ECw between both groups, and between different levels and causes of amputation. A second analysis investigated the association between self-selected walking speed and ECw in people with an amputation. Out of 526 identified articles, 25 were included in the meta-analysis and an additional 30 in the walking speed analysis. Overall, people with a lower-limb amputation have significantly higher ECw compared to people without an amputation. People with vascular transfemoral amputations showed the greatest difference (+102%) in ECw. The smallest difference (+12%) was found for people with nonvascular transtibial amputations. Slower self-selected walking speed was associated with substantial increases in ECw. This study provides general estimates on the ECw in people with a lower-limb amputation, quantifying the differences as a function of level and cause of amputation, as well as the relationship with walking speed.

Sections du résumé

BACKGROUND BACKGROUND
Energy cost of walking (ECw) is an important determinant of walking ability in people with a lower-limb amputation. Large variety in estimates of ECw has been reported, likely because of the heterogeneity of this population in terms of level and cause of amputation and walking speed.
OBJECTIVES OBJECTIVE
To assess (1) differences in ECw between people with and without a lower-limb amputation, and between people with different levels and causes of amputation, and (2) the association between ECw and walking speed.
STUDY DESIGN METHODS
Systematic review and meta-analysis.
METHODS METHODS
We included studies that compared ECw in people with and without a lower-limb amputation. A meta-analysis was done to compare ECw between both groups, and between different levels and causes of amputation. A second analysis investigated the association between self-selected walking speed and ECw in people with an amputation.
RESULTS RESULTS
Out of 526 identified articles, 25 were included in the meta-analysis and an additional 30 in the walking speed analysis. Overall, people with a lower-limb amputation have significantly higher ECw compared to people without an amputation. People with vascular transfemoral amputations showed the greatest difference (+102%) in ECw. The smallest difference (+12%) was found for people with nonvascular transtibial amputations. Slower self-selected walking speed was associated with substantial increases in ECw.
CONCLUSION CONCLUSIONS
This study provides general estimates on the ECw in people with a lower-limb amputation, quantifying the differences as a function of level and cause of amputation, as well as the relationship with walking speed.

Identifiants

pubmed: 34538817
doi: 10.1097/PXR.0000000000000035
pii: 00006479-202110000-00008
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

417-427

Informations de copyright

Copyright © 2021 International Society for Prosthetics and Orthotics.

Références

Fard B, Dijkstra PU, Stewart RE, et al. Incidence rates of dysvascular lower extremity amputation changes in Northern Netherlands: a comparison of three cohorts of 1991-1992, 2003-2004 and 2012-2013. PLoS One 2018; 13: e0204623.
Rommers G. M., Vos L. D. W., Groothoff J. W., Schuiling C. H., Eisma W. H. (1997). Epidemiology of lower limb amputees in the north of The Netherlands: aetiology, discharge destination and prosthetic use. Prosthetics and Orthotics International, 21(2), 92–99.
Davies B, Datta D. Mobility outcome following unilateral lower limb amputation. Prosthet Orthot Int 2003; 27: 186–190.
MacKenzie EJ, Bosse MJ, Castillo RC, et al. Functional outcomes following trauma-related lower-extremity amputation. JBJS 2004; 86: 1636–1645.
Sansam K, Neumann V, O'Connor R, et al. Predicting walking ability following lower limb amputation: a systematic review of the literature. J Rehabil Med 2009; 41: 593–603.
Waters R, Perry J, Antonelli D, et al. Energy cost of walking of amputees: the influence of level of amputation. J Bone Joint Surg Am 1976; 58: 42–46.
Van Velzen J, van Bennekom CA, Polomski W, et al. Physical capacity and walking ability after lower limb amputation: a systematic review. Clin Rehabil 2006; 20: 999–1016.
Franceschini M, Rampello A, Agosti M, et al. Walking performance: correlation between energy cost of walking and walking participation. New statistical approach concerning outcome measurement. PloS One 2013; 8: e56669.
Houdijk H, Pollmann E, Groenewold M, et al. The energy cost for the step-to-step transition in amputee walking. Gait Posture 2009; 30: 35–40.
Kuo AD, Donelan JM. Dynamic principles of gait and their clinical implications. Phys Ther 2010; 90: 157–174.
Meinders M, Gitter A, Czerniecki JM. The role of ankle plantar flexor muscle work during walking. Scand J Rehabil Med 1998; 30: 39–46.
Lamoth CJ, Ainsworth E, Polomski W, et al. Variability and stability analysis of walking of transfemoral amputees. Med Eng Phys 2010; 32: 1009–1014.
Kendell C, Lemaire E, Dudek N, et al. Indicators of dynamic stability in transtibial prosthesis users. Gait Posture 2010; 31: 375–379.
Viton JM, Mouchnino L, Mille M, et al. Equilibrium and movement control strategies in trans‐tibial amputees. Prosthet Orthot Int 2000; 24: 108–116.
Hak L, van Dieën JH, van der Wurff P, et al. Walking in an unstable environment: strategies used by transtibial amputees to prevent falling during gait. Arch Phys Med Rehabil 2013; 94: 2186–2193.
Houdijk H. Effects of balance support on energy cost of walking in people with lower limb amputation. Arch Phys Med Rehabil 2020; 102: 1340–1346.e3.
Waters RL, Mulroy S. The energy expenditure of normal and pathologic gait. Gait Posture 1999; 9: 207–231.
Esposito ER, Rodriguez KM, Ràbago CA, et al. Does unilateral transtibial amputation lead to greater metabolic demand during walking. J Rehabil Res Dev 2014; 51: 1287–1296.
Russell Esposito E, Rábago CA, Wilken J. The influence of traumatic transfemoral amputation on metabolic cost across walking speeds. Prosthet Orthot Int 2018; 42: 214–222.
Gailey R, Wenger M, Raya M, et al. Energy expenditure of trans-tibial amputees during ambulation at self-selected pace. Prosthet Orthot Int 1994; 18: 84–91.
Mengelkoch L, Kahle J, Highsmith M. Energy costs & performance of transtibial amputees & non-amputees during walking & running. Int J Sports Med 2014; 35: 1223–1228.
Delussu AS, Paradisi F, Brunelli S, et al. Comparison between SACH foot and a new multiaxial prosthetic foot during walking in hypomobile transtibial amputees: physiological responses and functional assessment. Eur J Phys Rehabil Med 2016; 52: 304–309.
Paysant J, Beyaert C, Datié AM, et al. Influence of terrain on metabolic and temporal gait characteristics of unilateral transtibial amputees. J Rehabil Res Dev 2006; 43: 153–160.
Starholm IM, Mirtaheri P, Kapetanovic N, et al. Energy expenditure of transfemoral amputees during floor and treadmill walking with different speeds. Prosthet Orthot Int 2016; 40: 336–342.
Genin JJ, Bastien GJ, Franck B, et al. Effect of speed on the energy cost of walking in unilateral traumatic lower limb amputees. Eur J Appl Physiol 2008; 103: 655.
Wezenberg D, van der Woude LH, Faber WX, et al. Relation between aerobic capacity and walking ability in older adults with a lower-limb amputation. Arch Phys Med Rehabil 2013; 94: 1714–1720.
Traballesi M, Porcacchia P, Averna T, et al. Energy cost of walking measurements in subjects with lower limb amputations: a comparison study between floor and treadmill test. Gait Posture 2008; 27: 70–75.
Wells G, Shea B, O'Connell D, et al. Newcastle-Ottawa Quality Assessment Scale Cohort Studies. University of Ottawa. Ottawa 2014.
Garby L, Astrup A. The relationship between the respiratory quotient and the energy equivalent of oxygen during simultaneous glucose and lipid oxidation and lipogenesis. Acta Physiol Scand 1987; 129: 443–444.
Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA. Cochrane Handbook for Systematic Reviews of Interventions. 2nd Edition. Chichester (UK): John Wiley & Sons, 2019.
Eckard CS, Pruziner AL, Sanchez AD, et al. Metabolic and body composition changes in first year following traumatic amputation. J Rehabil Res Dev 2015; 52.
Ganguli S, Datta S, Chatterjee B, et al. Metabolic cost of walking at different speeds with patellar tendon-bearing prosthesis. J Appl Physiol 1974; 36: 440–443.
Jaegers SM, Vos LD, Rispens P, et al. The relationship between comfortable and most metabolically efficient walking speed in persons with unilateral above-knee amputation. Arch Phys Med Rehabil 1993; 74: 521–525.
Kark L, Vickers D, McIntosh A, et al. Use of gait summary measures with lower limb amputees. Gait Posture 2012; 35: 238–243.
Ladlow P, Nightingale TE, McGuigan MP, et al. Impact of anatomical placement of an accelerometer on prediction of physical activity energy expenditure in lower-limb amputees. PloS One 2017; 12: e0185731.
Herr HM, Grabowski AM. Bionic ankle–foot prosthesis normalizes walking gait for persons with leg amputation. Proc Biol Sci 2012; 279: 457–464.
Pinzur MS, Gold J, Schwartz D, et al. Energy demands for walking in dysvascular amputees as related to the level of amputation. Orthopedics 1992; 15: 1033–1037.
Garcia MMdN, Lima JRPd, Costa Junior JD, et al. Energy expenditure and cardiovascular response to traumatic lower limb amputees' gait. Fisioterapia em Movimento 2015; 28: 259–268.
Schnall BL, Wolf EJ, Bell JC, et al. Metabolic analysis of male servicemembers with transtibial amputations carrying military loads. J Rehabil Res Dev 2012; 49.
Highsmith MJ, Kahle JT, Bongiorni DR, et al. Safety, energy efficiency, and cost efficacy of the C-Leg for transfemoral amputees: a review of the literature. Prosthet Orthot Int 2010; 34: 362–377.
Molen NH, Rozendal RH, Boon W. Graphic representation of the relationship between oxygen consumption and characteristics of normal gait of the human male. Proc K Ned Akaw Wet C 1972; 75: 305–314.
Zarrugh M, Todd F, Ralston H. Optimization of energy expenditure during level walking. Eur J Appl Physiol Occup Physiol 1974; 33: 293–306.
Miller WC, Speechley M, Deathe AB. Balance confidence among people with lower-limb amputations. Phys Ther 2002; 82: 856–865.
Wezenberg D, de Haan A, Faber WX, et al. Peak oxygen consumption in older adults with a lower limb amputation. Arch Phys Med Rehabil 2012; 93: 1924–1929.
van Schaik L, Geertzen JH, Dijkstra PU, et al. Metabolic costs of activities of daily living in persons with a lower limb amputation: a systematic review and meta-analysis. PloS One 2019; 14: e0213256.
Kahle JT, Highsmith MJ, Schaepper H, et al. Predicting walking ability following lower limb amputation: an updated systematic literature review. Technol Innovat 2016; 18: 125.
Carse B, Scott H, Brady L, et al. A characterisation of established unilateral transfemoral amputee gait using 3D kinematics, kinetics and oxygen consumption measures. Gait Posture 2020; 75: 98–104.
Chin T, Sawamura S, Shiba R, et al. Effect of an Intelligent Prosthesis (IP) on the walking ability of young transfemoral amputees: comparison of IP users with able-bodied people. Am J Phys Med Rehabil 2003; 82: 447–451.
Gailey R, Nash MS, Atchley T, et al. The effects of prosthesis mass on metabolic cost of ambulation in non-vascular trans-tibial amputees. Prosthet Orthot Int 1997; 21: 9–16.
Gailey R, Lawrence D, Burditt C, et al. The CAT-CAM socket and quadrilateral socket: a comparison of energy cost during ambulation. Prosthet Orthot Int 1993; 17: 95–100.
Ganguli S, Bose KS, Datta SR. Performance of BK amputees using PTB prostheses. Acta Orthop Scand 1975; 46: 123–134.
Gardinier ES, Kelly BM, Wensman J, et al. A controlled clinical trial of a clinically-tuned powered ankle prosthesis in people with transtibial amputation. Clin Rehabil 2018; 32: 319–329.
Gitter A, Czerniecki J, Weaver K. A reassessment of center-of-mass dynamics as a determinate of the metabolic inefficiency of above-knee amputee ambulation. Am J Phys Med Rehabil 1995; 74: 332–338.
Gjovaag T, Starholm IM, Mirtaheri P, et al. Assessment of aerobic capacity and walking economy of unilateral transfemoral amputees. Prosthet Orthot Int 2014; 38: 140–147.
Gjovaag T, Mirtaheri P, Starholm IM. Carbohydrate and fat oxidation in persons with lower limb amputation during walking with different speeds. Prosthet Orthot Int 2018; 42: 304–310.
Hsu M-J, Nielsen DH, Yack J, et al. Physiological comparisons of physically active persons with transtibial amputation using static and dynamic prostheses versus persons with nonpathological gait during multiple-speed walking. JPO J Prosthetics Orthot 2000; 12: 60–67.
Hunter D, Cole ES, Murray JM, et al. Energy expenditure of below-knee amputees during harness-supported treadmill ambulation. J Orthop Sports Phys Ther 1995; 21: 268–276.
Ijmker T, Houdijk H, Lamoth CJ, et al. Energy cost of balance control during walking decreases with external stabilizer stiffness independent of walking speed. J Biomech 2013; 46: 2109–2114.
Jarvis HL, Bennett AN, Twiste M, et al. Temporal spatial and metabolic measures of walking in highly functional individuals with lower limb amputations. Arch Phys Med Rehabil 2017; 98: 1389–1399.
Mengelkoch LJ, Kahle JT, Highsmith MJ. Energy costs and performance of transfemoral amputees and non-amputees during walking and running: a pilot study. Prosthet Orthot Int 2017; 41: 484–491.
Esposito ER, Choi HS, Darter BJ, et al. Can real-time visual feedback during gait retraining reduce metabolic demand for individuals with transtibial amputation? PloS One 2017; 12: e0171786.
Russell Esposito E, Aldridge Whitehead JM, Wilken JM. Step-to-step transition work during level and inclined walking using passive and powered ankle–foot prostheses. Prosthet Orthot Int 2016; 40: 311–319.
Askew GN, McFarlane LA, Minetti AE, et al. Energy cost of ambulation in trans-tibial amputees using a dynamic-response foot with hydraulic versus rigid “ankle”: insights from body centre of mass dynamics. J NeuroEng Rehabil 2019; 16: 39.
Barth DG, Schumacher L, Thomas SS. Gait analysis and energy cost of below-knee amputees wearing six different prosthetic feet. JPO J Prosthetics Orthot 1992; 4: 63–75.
Bell JC, Wolf EJ, Schnall BL, et al. Transfemoral amputations: is there an effect of residual limb length and orientation on energy expenditure? Clin Orthop Relat Res 2014; 472: 3055–3061.
Bellmann M, Schmalz T, Blumentritt S. Comparative biomechanical analysis of current microprocessor-controlled prosthetic knee joints. Arch Phys Med Rehabil 2010; 91: 644–652.
Buckley JG, Jones SF, Birch KM. Oxygen consumption during ambulation: comparison of using a prosthesis fitted with and without a tele-torsion device. Arch Phys Med Rehabil 2002; 83: 576–581.
Buckley JG, Spence WD, Solomonidis SE. Energy cost of walking: comparison of “intelligent prosthesis” with conventional mechanism. Arch Phys Med Rehabil 1997; 78: 330–333.
Cao W, Zhao W, Yu H, et al. Maximum swing flexion or gait symmetry: a comparative evaluation of control targets on metabolic energy expenditure of amputee using intelligent prosthetic knee. BioMed Res Int 2018; 2018: 2898546.
Casillas J-M, Dulieu V, Cohen M, et al. Bioenergetic comparison of a new energy-storing foot and SACH foot in traumatic below-knee vascular amputations. Arch Phys Med Rehabil 1995; 76: 39–44.
Darter BJ, Wilken JM. Gait training with virtual reality–based real-time feedback: improving gait performance following transfemoral amputation. Phys Ther 2011; 91: 1385–1394.
Darter BJ, Wilken JM. Energetic consequences of using a prosthesis with adaptive ankle motion during slope walking in persons with a transtibial amputation. Prosthet Orthot Int 2014; 38: 5–11.
Detrembleur C, Vanmarsenille JM, De Cuyper F, et al. Relationship between energy cost, gait speed, vertical displacement of centre of body mass and efficiency of pendulum-like mechanism in unilateral amputee gait. Gait Posture 2005; 21: 333–340.
Göktepe AS, Cakir B, Yilmaz B, et al. Energy expenditure of walking with prostheses: comparison of three amputation levels. Prosthet Orthot Int 2010; 34: 31–36.
Grabowski AM, Rifkin J, Kram R. K3 Promoter™ prosthetic foot reduces the metabolic cost of walking for unilateral transtibial amputees. JPO J Prosthetics Orthot 2010; 22: 113–120.
Graham LE, Datta D, Heller B, et al. A comparative study of oxygen consumption for conventional and energy-storing prosthetic feet in transfemoral amputees. Clin Rehabil 2008; 22: 896–901.
Hsu M-J, Nielsen DH, Lin-Chan S-J, et al. The effects of prosthetic foot design on physiologic measurements, self-selected walking velocity, and physical activity in people with transtibial amputation. Arch Phys Med Rehabil 2006; 87: 123–129.
Kirker S, Keymer S, Talbot J, et al. An assessment of the intelligent knee prosthesis. Clin Rehabil 1996; 10: 267–273.
Lin-Chan S-J, Nielsen DH, Yack HJ, et al. The effects of added prosthetic mass on physiologic responses and stride frequency during multiple speeds of walking in persons with transtibial amputation. Arch Phys Med Rehabil 2003; 84: 1865–1871.
Macfarlane PA, Nielsen DH, Shurr DG, et al. Transfemoral amputee physiological requirements: comparisons between SACH foot walking and Flex-Foot walking. JPO J Prosthetics Orthot 1997; 9: 138–143.
McDonald CL, Kramer PA, Morgan SJ, et al. Energy expenditure in people with transtibial amputation walking with crossover and energy storing prosthetic feet: a randomized within-subject study. Gait Posture 2018; 62: 349–354.
Orendurff MS, Segal AD, Klute GK, et al. Gait efficiency using the C-Leg. J Rehabil Res Dev 2006; 43: 239.
Rosenblatt NJ, Ehrhardt T, Fergus R, et al. Effects of vacuum-assisted socket suspension on energetic costs of walking, functional mobility, and prosthesis-related quality of life. JPO J Prosthetics Orthot 2017; 29: 65–72.
Schmalz T, Blumentritt S, Jarasch R. Energy expenditure and biomechanical characteristics of lower limb amputee gait: the influence of prosthetic alignment and different prosthetic components. Gait Posture 2002; 16: 255–263.
Seymour R, Engbretson B, Kott K, et al. Comparison between the C-leg® microprocessor-controlled prosthetic knee and non-microprocessor control prosthetic knees: A preliminary study of energy expenditure, obstacle course performance, and quality of life survey. Prosthet Orthot Int 2007; 31: 51–61.
Smith JD, Martin PE. Effects of prosthetic mass distribution on metabolic costs and walking symmetry. J Appl Biomech 2013; 29: 317–328.
Starholm I-M, Gjovaag T, Mengshoel AM. Energy expenditure of transfemoral amputees walking on a horizontal and tilted treadmill simulating different outdoor walking conditions. Prosthet Orthot Int 2010; 34: 184–194.
Tekin L, Safaz Ý, Göktepe AS, et al. Comparison of quality of life and functionality in patients with traumatic unilateral below knee amputation and salvage surgery. Prosthet Orthot Int 2009; 33: 17–24.
Torburn L, Powers CM, Guiterrez R, et al. Energy expenditure during ambulation in dysvascular and traumatic below-knee amputees: a comparison of five prosthetic feet. J Rehabil Res Dev 1995; 32: 111.
Traballesi M, Delussu AS, Averna T, et al. Energy cost of walking in transfemoral amputees: comparison between Marlo Anatomical Socket and Ischial Containment Socket. Gait Posture 2011; 34: 270–274.
Hsu MJ, Nielsen DH, Yack HJ, et al. Physiological measurements of walking and running in people with transtibial amputations with 3 different prostheses. J Orthop Sports Phys Ther 1999; 29: 526–533.
Macfarlane R, Jeffcoate W. Factors contributing to the presentation of diabetic foot ulcers. Diabet Med 1997; 14: 867–870.
Rosenblatt NJ, Bauer A, Grabiner MD. Relating minimum toe clearance to prospective, self-reported, trip-related stumbles in the community. Prosthet Orthot Int 2017; 41: 387–392.
IJmker T, Noten S, Lamoth C, et al. Can external lateral stabilization reduce the energy cost of walking in persons with a lower limb amputation? Gait Posture 2014; 40: 616–621.

Auteurs

Sanne Ettema (S)

Heliomare Research and Development, Wijk aan Zee, the Netherlands.
Amsterdam Movement Science, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.

Elmar Kal (E)

Department of Clinical Sciences, Division of Physiotherapy, Brunel University London, London, United Kingdom.

Han Houdijk (H)

University of Groningen, University Medical Center Groningen, Center for Human Movement Sciences, Groningen, the Netherlands.

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