Deployment of the Water Drinking Test and iCare HOME Phasing for Intraocular Pressure Profiling in Glaucoma Evaluation.


Journal

Optometry and vision science : official publication of the American Academy of Optometry
ISSN: 1538-9235
Titre abrégé: Optom Vis Sci
Pays: United States
ID NLM: 8904931

Informations de publication

Date de publication:
01 11 2021
Historique:
pubmed: 21 9 2021
medline: 22 3 2022
entrez: 20 9 2021
Statut: ppublish

Résumé

Intraocular pressure (IOP) profiling is an important component of the glaucoma examination. Two techniques for profiling are the water drinking test (WDT) and iCare HOME phasing, but the correlations between techniques and their ease of deployment have not been studied. These questions are important in determining suitability for clinical deployment. This study aimed to compare the IOP results of the WDT and iCare HOME phasing in patients with suspected or newly diagnosed glaucoma. Ninety-eight consecutive patients attending a glaucoma clinic underwent IOP profiling using both techniques. For the WDT, patients ingested 10 mL/kg body weight of water after a baseline applanation IOP measurement and then underwent serial IOP measurements approximately every 15 minutes, ceasing after 30 minutes of consecutive measurements within 3 mmHg of baseline. Patients successfully certified for self-administration of the iCare HOME were loaned the instrument for 1 week and instructed to take four measurements per day. Twenty-seven patients (28%) successfully obtained four measurements per day using iCare HOME, and 96 patients (98%) were able to complete the WDT. Intraocular pressure profiles showed no difference between the time for peak IOP and across nearly all IOP parameters obtained from profiling except for the standard deviation of IOP measurements obtained using the iCare HOME (P = .005). There were moderate correlations between peak IOPs obtained using each technique (r = 0.67, P = .001, right eye; r = 0.66, P = .002, left eye) but no correlation between the daily range (iCare HOME) or peak-trough difference (WDT; r = 0.21, P = .28, right eye; r = 0.27, P = .02, left eye). Bland-Altman analysis returned similar results for peak and range. Intraocular pressure profiling using both techniques can reveal the peak IOP, and these measurements are strongly correlated. Most patients were unable to complete the iCare HOME according to the manufacturer's recommendations. Clinicians should select the most appropriate technique for each patient.

Identifiants

pubmed: 34538849
doi: 10.1097/OPX.0000000000001806
pii: 00006324-202111000-00016
doi:

Substances chimiques

Water 059QF0KO0R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1321-1331

Informations de copyright

Copyright © 2021 American Academy of Optometry.

Déclaration de conflit d'intérêts

Conflict of Interest Disclosure: Guide Dogs NSW/ACT provides funding for clinical service delivery at the Centre for Eye Health where these data were collected. JP and MK also receive salary support from Guide Dogs NSW/ACT. The funding body had no role in the design and conduct of the study, or the decision to disseminate this research. iCare Finland Oy contributed, in part, several of the iCare HOME instruments and disposable probes used for the delivery of clinical services at the Centre for Eye Health. iCare Finland had no role in the design and conduct of the study, or the decision to disseminate this research.

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