Persistence of virus-neutralizing antibodies in horses inoculated with two doses of a live equine herpesvirus type 1 vaccine with different vaccination intervals.
equine herpesvirus type-1
persistence
vaccination interval
virus-neutralizing antibody
Journal
Journal of equine science
ISSN: 1340-3516
Titre abrégé: J Equine Sci
Pays: Japan
ID NLM: 9503751
Informations de publication
Date de publication:
2021
2021
Historique:
received:
19
02
2021
accepted:
30
04
2021
entrez:
20
9
2021
pubmed:
21
9
2021
medline:
21
9
2021
Statut:
ppublish
Résumé
The antibody response in horses inoculated with 2 doses of a live equine herpesvirus type 1 vaccine with different vaccination intervals (1 to 3 months) was evaluated with regard to the persistence of virus-neutralizing (VN) antibodies. The durations for which the geometric mean VN titers were maintained significantly higher than those before the first vaccination (P<0.05) were up to 5 months in horses that received the vaccination with a 1-month interval (n=17) and 7 months for those that received it with a 2-month (n=17) or 3-month interval (n=14 or 17). The vaccination program with the 2-month interval was the most effective in maintaining VN antibodies for a long duration with the smallest gap of antibody decline between the first and second vaccinations.
Identifiants
pubmed: 34539211
doi: 10.1294/jes.32.99
pii: 2112
pmc: PMC8437755
doi:
Types de publication
Journal Article
Langues
eng
Pagination
99-102Informations de copyright
©2021 The Japanese Society of Equine Science.
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