Mechanism and adverse effects of COVID-19 drugs: a basic review.

COVID-19 Mechanism adverse effect drugs

Journal

International journal of physiology, pathophysiology and pharmacology
ISSN: 1944-8171
Titre abrégé: Int J Physiol Pathophysiol Pharmacol
Pays: United States
ID NLM: 101521074

Informations de publication

Date de publication:
2021
Historique:
received: 09 12 2020
accepted: 01 07 2021
entrez: 20 9 2021
pubmed: 21 9 2021
medline: 21 9 2021
Statut: epublish

Résumé

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) is chronic, inflammatory. Although the exact mechanisms of COVID-19 have not been yet discovered some drugs are found helpful for its treatment. These drugs which are divided into some lines therapies, have demonstrated to be helpful for COVID-19 patients based on immune basic and its antiviral properties of the disease. Previous studies have been indicated that deterioration of COVID-19 condition is associated with a weaker immune system. Most of these therapies impact on the immune system and immune cells. Beside many beneficial effects of these drugs, some adverse effects (AE) have been reported in many experiments and clinical trials among patients suffering from COVID-19. In this review, we conclude some AEs of vitamin-D, zinc, remdesivir, hydroxychloroquine or chloroquine, azithromycin, dexamethasone, amantadine, aspirin reported in different papers and we continue the rest of the drugs in second part of our review article.

Identifiants

pubmed: 34540130
pmc: PMC8446775

Types de publication

Journal Article Review

Langues

eng

Pagination

102-109

Informations de copyright

IJPPP Copyright © 2021.

Déclaration de conflit d'intérêts

None.

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Auteurs

Nadia Mohammad Zadeh (N)

School of Medicine, Islamic Azad University Tehran Faculty of Medicine Tehran, Iran.

Nazli Sadat Mashinchi Asl (NS)

Postdoc Associate, Texas Medical Center Texas, USA.

Khatereh Forouharnejad (K)

School of Medicine, Islamic Azad University of Najafabad Branch Isfahan, Iran.

Keyvan Ghadimi (K)

School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

Sara Parsa (S)

School of Medicine, Islamic Azad University of Najafabad Branch Isfahan, Iran.

Sima Mohammadi (S)

School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

Ashkan Omidi (A)

School of Medicine, Islamic Azad University Tehran Faculty of Medicine Tehran, Iran.

Classifications MeSH