Hyperleukocytosis-induced stroke and tonsillar herniation: Case report.
Hyperleukocytosis
Hyperviscosity
Ischemic stroke
Leukemia
Tonsillar herniation
Journal
Annals of medicine and surgery (2012)
ISSN: 2049-0801
Titre abrégé: Ann Med Surg (Lond)
Pays: England
ID NLM: 101616869
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
01
08
2021
revised:
23
08
2021
accepted:
02
09
2021
entrez:
20
9
2021
pubmed:
21
9
2021
medline:
21
9
2021
Statut:
epublish
Résumé
and Importance: Acute ischemic stroke is a rare event in children with leukemia, yet with long-term morbidity, substantial health, and economic cost. Central nervous system (CNS) leukemic involvement and chemotherapy-related stroke are the most common causes. Hyperleukocytosis induced stroke is very rarely reported. A 2-year-old male child presented with hyperleukocytosis (leukocyte count was 320x10 Hyperviscosity secondary to hyperleukocytosis was considered to be the most likely explanation for this patient stroke after excluding thrombophilia and leukemic infiltration. Prompt management with hydration and careful chemotherapy resulted in good outcome in our patient. This case demonstrate the value of early recognition and prompt management of posterior circulation ischemic stroke in children with leukemia and hyperleukocytosis at presentation.
Identifiants
pubmed: 34540210
doi: 10.1016/j.amsu.2021.102776
pii: S2049-0801(21)00726-3
pmc: PMC8441068
doi:
Types de publication
Case Reports
Langues
eng
Pagination
102776Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors have no competing conflict of interest.
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