Sarcoidosis: Various Presentations, Coexisting Diseases and Malignancies.
association
complex presentation
malignancy
other diseases
pathology
sarcoidosis
thyroid
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Aug 2021
Aug 2021
Historique:
received:
23
06
2021
accepted:
07
08
2021
entrez:
20
9
2021
pubmed:
21
9
2021
medline:
21
9
2021
Statut:
epublish
Résumé
Sarcoidosis is a rare, chronic inflammatory disease with a characteristic non-caseating granuloma formation. It affects women more than men. The lung is the most commonly affected organ, however, extrapulmonary involvement is also seen. Sarcoidosis can affect any organ or tissue and can also involve multiple organs simultaneously. As a disease, it shares clinical symptoms with a variety of autoimmune, non-autoimmune disorders and malignancies. Not only it mimics clinically, but it also coexists with these diseases, posing a significant diagnostic challenge. During this literature review, we obtained data from the previously published PubMed articles within the last five years and reviewed the possible etiological association and clinical coexistence between sarcoidosis and other diseases/malignancies. We aimed to determine the common clinical manifestations, various complex presentations of sarcoidosis and pathophysiological considerations for the association, and to emphasize the link with other diseases, particularly thyroid disorders/malignancies. Physicians should be aware of these associated diseases and should always make a clinical suspicion when confronting a sarcoidosis patient. Thus, a comprehensive diagnostic evaluation for these associated conditions ought to be done in sarcoidosis patients to avoid any delay in the curative treatment for these coexisting diseases and to prevent substandard outcomes.
Identifiants
pubmed: 34540380
doi: 10.7759/cureus.16967
pmc: PMC8423115
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e16967Informations de copyright
Copyright © 2021, Gaddam et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Reumatol Clin (Engl Ed). 2021 Jan;17(1):49-51
pubmed: 31153889
Asia Ocean J Nucl Med Biol. 2020 Winter;8(1):74-78
pubmed: 32064287
Chest. 2017 Jun;151(6):e131-e134
pubmed: 28599946
BMJ Open. 2017 Jul 20;7(7):e016839
pubmed: 28729325
Reumatismo. 2018 Jul 06;70(2):106-110
pubmed: 29976045
QJM. 2003 Aug;96(8):553-61
pubmed: 12897340
Endocrinol Metab Clin North Am. 1991 Sep;20(3):645-54
pubmed: 1935922
J Dermatol. 2017 Apr;44(4):423-430
pubmed: 27786368
Clin Respir J. 2017 Sep;11(5):648-656
pubmed: 26470754
JAMA. 2011 Jan 26;305(4):391-9
pubmed: 21266686
Autoimmun Rev. 2016 Dec;15(12):1125-1128
pubmed: 27639841
HNO. 2017 Aug;65(8):695-708
pubmed: 28710538
BMJ Case Rep. 2016 Aug 05;2016:
pubmed: 27495178
Lung India. 2020 Sep-Oct;37(5):437-440
pubmed: 32883906
Int J Endocrinol Metab. 2017 Aug 22;15(4):e57199
pubmed: 29344035
Br J Cancer. 1974 Mar;29(3):247-51
pubmed: 4830144
J Clin Invest. 2007 Nov;117(11):3576-82
pubmed: 17975675
Ther Adv Chronic Dis. 2018 Aug 24;9(11):227-240
pubmed: 30364496
Indian J Pathol Microbiol. 2017 Oct-Dec;60(4):608-609
pubmed: 29323090
Br J Dermatol. 2013 Oct;169 Suppl 3:1-10
pubmed: 24098896
Eur Respir J. 1998 Oct;12(4):906-12
pubmed: 9817167
Eur Respir J. 2016 Mar;47(3):898-909
pubmed: 26585430
Front Endocrinol (Lausanne). 2017 Jul 31;8:184
pubmed: 28824545
Am J Ophthalmol. 2011 Jun;151(6):1074-1080.e1
pubmed: 21457924
QJM. 2012 Oct;105(10):981-95
pubmed: 22753675
Ann Intern Med. 1980 Mar;92(3):361-5
pubmed: 6243895
PLoS One. 2019 Oct 24;14(10):e0224138
pubmed: 31648281
Sarcoidosis Vasc Diffuse Lung Dis. 2019;36(4):318-324
pubmed: 32476968
Pan Afr Med J. 2019 Jun 07;33:92
pubmed: 31489070
ERJ Open Res. 2021 Mar 29;7(1):
pubmed: 33816601
J Arrhythm. 2016 Dec;32(6):474-480
pubmed: 27920832
Open Ophthalmol J. 2016 Apr 29;10:140-145
pubmed: 28484581
Eur J Endocrinol. 1996 Mar;134(3):331-6
pubmed: 8616531
Autoimmun Rev. 2019 Mar;18(3):287-292
pubmed: 30639646
Am J Med. 2019 Jan;132(1):48-51
pubmed: 30102910
BMJ Case Rep. 2018 Jun 8;2018:
pubmed: 29884710
Dermatol Clin. 2015 Jul;33(3):389-416
pubmed: 26143421
Actas Dermosifiliogr. 2016 Dec;107(10):876-878
pubmed: 27555517
Med Clin North Am. 2011 Nov;95(6):1223-34
pubmed: 22032436
Curr Opin Pulm Med. 2019 Sep;25(5):539-553
pubmed: 31365389
Pan Afr Med J. 2016 May 06;24:23
pubmed: 27583087
Thorax. 2011 Feb;66(2):144-50
pubmed: 21139119
Oncol Lett. 2017 Dec;14(6):7643-7652
pubmed: 29344212
Curr Opin Pulm Med. 2002 Sep;8(5):452-6
pubmed: 12172452
Curr Opin Pulm Med. 2018 Sep;24(5):504-512
pubmed: 29985181
Clin Endocrinol (Oxf). 1997 Apr;46(4):467-72
pubmed: 9196610
Sarcoidosis Vasc Diffuse Lung Dis. 2007 Sep;24(2):148-52
pubmed: 18496986
BJR Case Rep. 2020 May 14;6(3):20190125
pubmed: 32922836
Lancet. 2014 Mar 29;383(9923):1155-67
pubmed: 24090799
Ophthalmic Plast Reconstr Surg. 2020 May/Jun;36(3):284-291
pubmed: 31789785
Am J Respir Crit Care Med. 1999 Nov;160(5 Pt 1):1668-72
pubmed: 10556138
Eye (Lond). 2018 Feb;32(2):248-261
pubmed: 29125145
Endocrinol Diabetes Metab Case Rep. 2020 Mar 13;2020:
pubmed: 32168468
J Clin Invest. 1981 Jan;67(1):86-92
pubmed: 6969734
Handb Clin Neurol. 2014;119:305-33
pubmed: 24365304
Eur Respir J. 2015 Jan;45(1):269-72
pubmed: 25102965
BMJ Case Rep. 2019 Jan 22;12(1):
pubmed: 30674496