Excess Body Weight and Gastroesophageal Reflux Disease.

Bariatric surgery Excess body weight Gastroesophageal reflux disease Obesity Reflux

Journal

Visceral medicine

ISSN: 2297-4725

Titre abrégé: Visc Med

Pays: Switzerland

ID NLM: 101681546

Informations de publication

Date de publication:
Aug 2021

Historique:

received: 27 01 2021

accepted: 22 03 2021

entrez: 20 9 2021

pubmed: 21 9 2021

medline: 21 9 2021

Statut: ppublish

Résumé

Gastroesophageal reflux disease (GERD) is strongly associated with excess body weight. GERD is characterized by typical symptoms with or without mucosal damage because of retrograde flow of gastric content into the esophagus. An ineffective esophagogastric junction (EGJ) combined with anatomical abnormalities is considered to be causative. The incidence of GERD is strongly associated with excess body weight, reflecting the pathophysiological relevance of the abdominothoracic pressure gradient. Weight loss has been demonstrated to be an effective therapy for GERD combined with obesity. In cases in which surgical therapy is indicated, traditional antireflux surgery has led to equivocal results, advocating a proximal Roux-en-Y gastric bypass in these patients to correct both GERD and excess body weight.

Sections du résumé

BACKGROUND BACKGROUND

Gastroesophageal reflux disease (GERD) is strongly associated with excess body weight.

SUMMARY CONCLUSIONS

GERD is characterized by typical symptoms with or without mucosal damage because of retrograde flow of gastric content into the esophagus. An ineffective esophagogastric junction (EGJ) combined with anatomical abnormalities is considered to be causative. The incidence of GERD is strongly associated with excess body weight, reflecting the pathophysiological relevance of the abdominothoracic pressure gradient.

KEY MESSAGE CONCLUSIONS

Weight loss has been demonstrated to be an effective therapy for GERD combined with obesity. In cases in which surgical therapy is indicated, traditional antireflux surgery has led to equivocal results, advocating a proximal Roux-en-Y gastric bypass in these patients to correct both GERD and excess body weight.

Identifiants

DOI: 10.1159/000516050 PMID: 34540942 PMC: PMC8406336

pubmed: 34540942

doi: 10.1159/000516050

pii: vis-0037-0267

pmc: PMC8406336

doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

267-272

Informations de copyright

Déclaration de conflit d'intérêts

The authors have no conflict of interests to declare.

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