Anterior Cruciate Ligament Reconstruction With Concomitant Meniscal Repair: Is Graft Choice Predictive of Meniscal Repair Success?

ACL reconstruction allograft autograft meniscal repair

Journal

Orthopaedic journal of sports medicine
ISSN: 2325-9671
Titre abrégé: Orthop J Sports Med
Pays: United States
ID NLM: 101620522

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 01 03 2021
accepted: 19 03 2021
entrez: 20 9 2021
pubmed: 21 9 2021
medline: 21 9 2021
Statut: epublish

Résumé

When meniscal repair is performed during anterior cruciate ligament (ACL) reconstruction (ACLR), the effect of ACL graft type on meniscal repair outcomes is unclear. The authors hypothesized that meniscal repairs would fail at the lowest rate when concomitant ACLR was performed with bone--patellar tendon--bone (BTB) autograft. Cohort study; Level of evidence, 3. Patients who underwent meniscal repair at primary ACLR were identified from a longitudinal, prospective cohort. Meniscal repair failures, defined as any subsequent surgical procedure addressing the meniscus, were identified. A logistic regression model was built to assess the association of graft type, patient-specific factors, baseline Marx activity rating score, and meniscal repair location (medial or lateral) with repair failure at 6-year follow-up. A total of 646 patients were included. Grafts used included BTB autograft (55.7%), soft tissue autograft (33.9%), and various allografts (10.4%). We identified 101 patients (15.6%) with a documented meniscal repair failure. Failure occurred in 74 of 420 (17.6%) isolated medial meniscal repairs, 15 of 187 (8%) isolated lateral meniscal repairs, and 12 of 39 (30.7%) of combined medial and lateral meniscal repairs. Meniscal repair failure occurred in 13.9% of patients with BTB autografts, 17.4% of patients with soft tissue autografts, and 19.4% of patients with allografts. The odds of failure within 6 years of index surgery were increased more than 2-fold with allograft versus BTB autograft (odds ratio = 2.34 [95% confidence interval, 1.12-4.92]; Meniscal repair location (medial vs lateral) and baseline activity level were the main drivers of meniscal repair outcomes. Graft type was ranked third, demonstrating that meniscal repairs performed with allograft were 2.3 times more likely to fail compared with BTB autograft. There was no significant difference in failure rates between BTB versus soft tissue autografts. NCT00463099 (ClinicalTrials.gov identifier).

Sections du résumé

BACKGROUND BACKGROUND
When meniscal repair is performed during anterior cruciate ligament (ACL) reconstruction (ACLR), the effect of ACL graft type on meniscal repair outcomes is unclear.
HYPOTHESIS OBJECTIVE
The authors hypothesized that meniscal repairs would fail at the lowest rate when concomitant ACLR was performed with bone--patellar tendon--bone (BTB) autograft.
STUDY DESIGN METHODS
Cohort study; Level of evidence, 3.
METHODS METHODS
Patients who underwent meniscal repair at primary ACLR were identified from a longitudinal, prospective cohort. Meniscal repair failures, defined as any subsequent surgical procedure addressing the meniscus, were identified. A logistic regression model was built to assess the association of graft type, patient-specific factors, baseline Marx activity rating score, and meniscal repair location (medial or lateral) with repair failure at 6-year follow-up.
RESULTS RESULTS
A total of 646 patients were included. Grafts used included BTB autograft (55.7%), soft tissue autograft (33.9%), and various allografts (10.4%). We identified 101 patients (15.6%) with a documented meniscal repair failure. Failure occurred in 74 of 420 (17.6%) isolated medial meniscal repairs, 15 of 187 (8%) isolated lateral meniscal repairs, and 12 of 39 (30.7%) of combined medial and lateral meniscal repairs. Meniscal repair failure occurred in 13.9% of patients with BTB autografts, 17.4% of patients with soft tissue autografts, and 19.4% of patients with allografts. The odds of failure within 6 years of index surgery were increased more than 2-fold with allograft versus BTB autograft (odds ratio = 2.34 [95% confidence interval, 1.12-4.92];
CONCLUSION CONCLUSIONS
Meniscal repair location (medial vs lateral) and baseline activity level were the main drivers of meniscal repair outcomes. Graft type was ranked third, demonstrating that meniscal repairs performed with allograft were 2.3 times more likely to fail compared with BTB autograft. There was no significant difference in failure rates between BTB versus soft tissue autografts.
REGISTRATION BACKGROUND
NCT00463099 (ClinicalTrials.gov identifier).

Identifiants

pubmed: 34541016
doi: 10.1177/23259671211033584
pii: 10.1177_23259671211033584
pmc: PMC8445540
doi:

Banques de données

ClinicalTrials.gov
['NCT00463099']

Types de publication

Journal Article

Langues

eng

Pagination

23259671211033584

Subventions

Organisme : NIAMS NIH HHS
ID : R01 AR053684
Pays : United States

Informations de copyright

© The Author(s) 2021.

Déclaration de conflit d'intérêts

One or more of the authors has declared the following potential conflict of interest or source of funding: Research reported in this publication was partially supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health under Award No. R01AR053684 (to K.P.S.) and under award No. K23AR066133, which supported a portion of M.H.J.’s professional effort. Contents of this article are solely the responsibility of the authors and do not necessarily represent official views of the National Institutes of Health. AOSSM checks author disclosures against the Open Payments Database (OPD). AOSSM has not conducted an independent investigation on the OPD and disclaims any liability or responsibility relating thereto.

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Auteurs

Hytham S Salem (HS)

CU Sports Medicine, Boulder, Colorado, USA.

Laura J Huston (LJ)

Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Alexander Zajichek (A)

Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.

Eric C McCarty (EC)

CU Sports Medicine, Boulder, Colorado, USA.

Armando F Vidal (AF)

CU Sports Medicine, Boulder, Colorado, USA.

Jonathan T Bravman (JT)

CU Sports Medicine, Boulder, Colorado, USA.

Kurt P Spindler (KP)

Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.

Rachel M Frank (RM)

CU Sports Medicine, Boulder, Colorado, USA.

Annunziato Amendola (A)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Jack T Andrish (JT)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Robert H Brophy (RH)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Morgan H Jones (MH)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Christopher C Kaeding (CC)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Robert G Marx (RG)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Matthew J Matava (MJ)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Richard D Parker (RD)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Michelle L Wolcott (ML)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Brian R Wolf (BR)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Rick W Wright (RW)

CU Sports Medicine, Boulder, Colorado, USA.
Department of Orthopaedics and Rehabilitation, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA.
Department of Orthopaedics, Cleveland Clinic Foundation, Garfield Heights, Ohio, USA.
Investigation performed at Cleveland Clinic, Cleveland, Ohio, USA; Vanderbilt University, Nashville, Tennessee, USA; and University of Colorado, Boulder, Colorado, USA.

Classifications MeSH