Carrier-free nanodrugs with efficient drug delivery and release for cancer therapy: From intrinsic physicochemical properties to external modification.
Carrier-free nanodrugs
Drug delivery and release
External modification
Intrinsic physicochemical properties
Therapeutic efficacy
Journal
Bioactive materials
ISSN: 2452-199X
Titre abrégé: Bioact Mater
Pays: China
ID NLM: 101685294
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
27
03
2021
revised:
23
06
2021
accepted:
30
06
2021
entrez:
20
9
2021
pubmed:
21
9
2021
medline:
21
9
2021
Statut:
epublish
Résumé
The considerable development of carrier-free nanodrugs has been achieved due to their high drug-loading capability, simple preparation method, and offering "all-in-one" functional platform features. However, the native defects of carrier-free nanodrugs limit their delivery and release behavior throughout the
Identifiants
pubmed: 34541398
doi: 10.1016/j.bioactmat.2021.06.035
pii: S2452-199X(21)00321-2
pmc: PMC8424425
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
220-240Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
ACS Nano. 2018 Nov 27;12(11):11041-11061
pubmed: 30481959
Sci Rep. 2017 Nov 7;7(1):14674
pubmed: 29116098
J Control Release. 2007 Feb 12;117(2):256-66
pubmed: 17188777
J Control Release. 2013 Nov 28;172(1):12-21
pubmed: 23920039
Nanoscale. 2012 Sep 7;4(17):5373-7
pubmed: 22814892
ACS Appl Mater Interfaces. 2017 Dec 20;9(50):43508-43519
pubmed: 29171263
Colloids Surf B Biointerfaces. 2019 Aug 1;180:313-318
pubmed: 31071571
ACS Nano. 2017 Apr 25;11(4):4086-4096
pubmed: 28334523
J Am Chem Soc. 2017 Oct 11;139(40):14021-14024
pubmed: 28945366
Eur J Pharm Sci. 2003 Feb;18(2):113-20
pubmed: 12594003
J Control Release. 2017 Jul 28;258:95-107
pubmed: 28501673
J Mater Chem B. 2019 Nov 28;7(44):6914-6923
pubmed: 31482166
Nanomedicine. 2015 Oct;11(7):1603-11
pubmed: 25989200
Adv Healthc Mater. 2017 Dec;6(24):
pubmed: 29076266
Angew Chem Int Ed Engl. 2018 Aug 27;57(35):11384-11388
pubmed: 30003656
Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1778-83
pubmed: 26831078
Biomaterials. 2014 May;35(15):4517-24
pubmed: 24612917
Nanoscale. 2018 Jul 9;10(26):12639-12649
pubmed: 29943786
Acta Pharm Sin B. 2019 Nov;9(6):1099-1112
pubmed: 31867159
Biomaterials. 2013 Nov;34(35):8960-7
pubmed: 23958027
ACS Appl Mater Interfaces. 2015 Jun 10;7(22):11908-20
pubmed: 25978458
Int J Cancer. 1992 May 8;51(2):244-9
pubmed: 1568792
ACS Nano. 2019 May 28;13(5):5591-5601
pubmed: 31070352
Nanomicro Lett. 2020 Sep 14;12(1):182
pubmed: 34138172
Adv Healthc Mater. 2012 Sep;1(5):537-47
pubmed: 23184788
Int J Nanomedicine. 2021 Mar 03;16:1775-1787
pubmed: 33692622
Biomater Sci. 2017 Aug 22;5(9):1889-1897
pubmed: 28681888
J Mater Sci Mater Med. 2015 Sep;26(9):234
pubmed: 26395359
Int J Pharm. 2019 Oct 30;570:118663
pubmed: 31493497
Acta Biomater. 2020 Jul 15;111:327-340
pubmed: 32434075
Bioconjug Chem. 2015 Dec 16;26(12):2497-506
pubmed: 26497258
J Mater Chem B. 2019 Feb 7;7(5):778-785
pubmed: 32254852
Theranostics. 2021 Apr 7;11(12):6019-6032
pubmed: 33897896
Adv Sci (Weinh). 2020 Feb 05;7(7):1903301
pubmed: 32274314
J Am Chem Soc. 2014 Aug 20;136(33):11748-56
pubmed: 25078892
J Am Chem Soc. 2010 Mar 31;132(12):4259-65
pubmed: 20218672
Biol Pharm Bull. 2013;36(6):892-9
pubmed: 23727912
J Control Release. 2017 Dec 10;267:203-213
pubmed: 28823674
Biomaterials. 2018 Jan;151:1-12
pubmed: 29040939
Small. 2019 May;15(20):e1805544
pubmed: 30924285
J Am Chem Soc. 2010 Jan 20;132(2):442-3
pubmed: 20020681
J Mater Chem B. 2020 Sep 21;8(35):7931-7940
pubmed: 32779670
ACS Appl Mater Interfaces. 2020 Jul 22;12(29):32477-32492
pubmed: 32578429
Biomaterials. 2018 Feb;155:25-40
pubmed: 29161627
ACS Appl Mater Interfaces. 2018 Aug 8;10(31):25983-25993
pubmed: 30014692
J Med Chem. 2013 Oct 10;56(19):7564-73
pubmed: 24028446
ACS Nano. 2013 Aug 27;7(8):6782-95
pubmed: 23822176
J Control Release. 2015 Feb 28;200:138-57
pubmed: 25545217
Theranostics. 2016 Jun 23;6(10):1703-16
pubmed: 27446502
Nanoscale. 2017 Nov 2;9(42):16365-16374
pubmed: 29052674
Nano Lett. 2015 Jan 14;15(1):313-8
pubmed: 25514014
Nanomedicine. 2019 Aug;20:102008
pubmed: 31121311
ACS Appl Mater Interfaces. 2020 Sep 30;12(39):43488-43500
pubmed: 32870657
Biomaterials. 2019 Feb;193:12-21
pubmed: 30550999
J Control Release. 2018 Jun 10;279:136-146
pubmed: 29655991
Nat Rev Cancer. 2017 Jan;17(1):20-37
pubmed: 27834398
Nanoscale. 2019 May 16;11(19):9457-9467
pubmed: 31042245
Adv Mater. 2017 Oct;29(40):
pubmed: 28891273
Polym Chem. 2013 Jan 7;4(1):133-143
pubmed: 23766781
Adv Sci (Weinh). 2018 May 09;5(7):1800155
pubmed: 30027047
Adv Mater. 2018 Dec;30(50):e1805557
pubmed: 30368972
ACS Appl Mater Interfaces. 2017 Oct 11;9(40):34650-34665
pubmed: 28920426
Nanoscale. 2015 Aug 28;7(32):13503-10
pubmed: 26199064
Acta Biomater. 2018 Apr 1;70:197-210
pubmed: 29408311
Int J Nanomedicine. 2018 Dec 06;13:8339-8354
pubmed: 30584304
Acta Biomater. 2018 Sep 1;77:228-239
pubmed: 30006314
Biomaterials. 2015 Feb;41:1-14
pubmed: 25522960
Nanoscale. 2019 Aug 29;11(34):15907-15916
pubmed: 31414111
Chem Commun (Camb). 2015 Jul 4;51(52):10403-18
pubmed: 26021457
Adv Drug Deliv Rev. 2020 Dec;167:170-188
pubmed: 32622022
Pharmaceutics. 2018 Aug 21;10(3):
pubmed: 30134537
J Control Release. 2020 May 10;321:589-601
pubmed: 32114091
Int J Pharm. 2019 Feb 10;556:217-225
pubmed: 30557679
Int J Pharm. 2011 Aug 30;415(1-2):293-300
pubmed: 21679755
J Mater Chem B. 2019 Aug 7;7(31):4758-4762
pubmed: 31389948
Int J Pharm. 2017 Apr 15;521(1-2):156-166
pubmed: 28223247
J Pharm Pharmacol. 2017 Aug;69(8):967-977
pubmed: 28464225
Chem Commun (Camb). 2012 Aug 21;48(65):8120-2
pubmed: 22766919
Biomater Sci. 2019 Jan 29;7(2):634-644
pubmed: 30534690
ACS Appl Mater Interfaces. 2019 Dec 26;11(51):48261-48270
pubmed: 31763809
Biomaterials. 2017 Oct;143:1-16
pubmed: 28755539
Cancer Metastasis Rev. 2008 Dec;27(4):655-64
pubmed: 18523731
J Mater Chem B. 2020 Jun 21;8(23):5109-5116
pubmed: 32412025
ACS Appl Mater Interfaces. 2019 Mar 13;11(10):9872-9883
pubmed: 30767506
ACS Nano. 2018 Nov 27;12(11):11446-11457
pubmed: 30345740
Small. 2015 Dec;11(46):6225-36
pubmed: 26488923
ACS Appl Mater Interfaces. 2019 Sep 18;11(37):33706-33715
pubmed: 31466443
J Control Release. 2021 Jan 10;329:805-832
pubmed: 33045313
J Control Release. 2016 May 28;230:34-44
pubmed: 27040815
Acta Pharm Sin B. 2019 Jul;9(4):675-689
pubmed: 31384529
Angew Chem Int Ed Engl. 2019 Mar 26;58(14):4632-4637
pubmed: 30695128
Mol Pharm. 2015 Jul 6;12(7):2328-36
pubmed: 25996874
J Mater Chem B. 2020 Aug 21;8(31):6765-6781
pubmed: 32315375
Nanotechnology. 2013 Jan 11;24(1):015103
pubmed: 23221098
J Am Chem Soc. 2018 Nov 7;140(44):14980-14989
pubmed: 30359020
J Pharm Pharmacol. 2004 Jul;56(7):827-40
pubmed: 15233860
Nat Commun. 2016 Nov 07;7:13443
pubmed: 27819653
Nat Nanotechnol. 2014 Nov;9(11):907-912
pubmed: 25282044
ACS Appl Mater Interfaces. 2018 Sep 12;10(36):30155-30162
pubmed: 30125081
Biomaterials. 2021 Jan;268:120557
pubmed: 33260095
Int J Pharm. 2009 May 21;373(1-2):116-23
pubmed: 19429296
J Control Release. 2018 May 28;278:127-139
pubmed: 29630985
Angiogenesis. 2009;12(1):91-100
pubmed: 19225898
Adv Healthc Mater. 2014 Sep;3(9):1475-85
pubmed: 24665009
Drug Deliv. 2017 Nov;24(1):51-60
pubmed: 28155539
Sci Adv. 2021 Feb 5;7(6):
pubmed: 33547067
Biomacromolecules. 2001 Summer;2(2):491-7
pubmed: 11749211
Mol Cancer. 2014 Aug 13;13:191
pubmed: 25128329
Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):4930-4
pubmed: 16549762
J Control Release. 2019 May 28;302:79-89
pubmed: 30946853
Cancer Res. 1995 Nov 15;55(22):5451-8
pubmed: 7585615
J Mater Chem B. 2018 Jun 14;6(22):3692-3702
pubmed: 32254832
Colloids Surf B Biointerfaces. 2019 Oct 1;182:110337
pubmed: 31306829
ACS Appl Mater Interfaces. 2019 May 1;11(17):15262-15275
pubmed: 30964624
Gynecol Oncol. 2009 Oct;115(1):90-96
pubmed: 19577796
Sci Rep. 2016 Nov 04;6:36614
pubmed: 27812039
Nano Lett. 2014;14(4):2181-8
pubmed: 24673373
J Control Release. 2009 Oct 15;139(2):127-32
pubmed: 19540888
J Am Chem Soc. 2012 Feb 1;134(4):2139-47
pubmed: 22191645
ACS Appl Mater Interfaces. 2015 Sep 2;7(34):19295-305
pubmed: 26270258
ACS Nano. 2015 Oct 27;9(10):9741-56
pubmed: 26390118
J Mater Chem B. 2017 Dec 14;5(46):9121-9129
pubmed: 32264593
ACS Appl Mater Interfaces. 2015 Nov 25;7(46):25553-9
pubmed: 26529185
PLoS One. 2010 Dec 23;5(12):e15787
pubmed: 21203423
J Control Release. 2010 Sep 15;146(3):264-75
pubmed: 20385184
Med Res Rev. 2020 Sep;40(5):1754-1775
pubmed: 32266734
J Cell Biol. 2003 Nov 24;163(4):871-8
pubmed: 14638862
Chem Commun (Camb). 2015 Jun 7;51(45):9343-5
pubmed: 25959901
Mol Pharm. 2019 Jul 1;16(7):3133-3144
pubmed: 31198046
Biomaterials. 2012 Nov;33(31):7803-9
pubmed: 22819497
ACS Nano. 2013 Mar 26;7(3):2056-67
pubmed: 23413798
Int J Mol Sci. 2018 Sep 28;19(10):
pubmed: 30274177
J Control Release. 2015 Dec 28;220(Pt B):600-7
pubmed: 26210440
Biomater Sci. 2019 Aug 20;7(9):3662-3674
pubmed: 31179466
Biomaterials. 2011 Nov;32(31):8010-20
pubmed: 21788069
Pharm Res. 2004 Jun;21(6):962-8
pubmed: 15212160
ACS Nano. 2016 Jun 28;10(6):5720-9
pubmed: 27223166
FEBS J. 2011 May;278(9):1429-43
pubmed: 21362138
Biomater Sci. 2020 Jan 1;8(1):462-472
pubmed: 31750450
J Mater Chem B. 2016 Apr 7;4(13):2332-2337
pubmed: 32263228
Proc Natl Acad Sci U S A. 2002 Oct 15;99(21):13481-6
pubmed: 12359872
Adv Healthc Mater. 2020 Oct;9(19):e2001128
pubmed: 32893507
Chem Soc Rev. 2012 Apr 7;41(7):2971-3010
pubmed: 22388185
Nano Lett. 2020 Mar 11;20(3):1781-1790
pubmed: 32091222
ACS Nano. 2017 Sep 26;11(9):8838-8848
pubmed: 28858467
Colloids Surf B Biointerfaces. 2017 Dec 1;160:649-660
pubmed: 29031225
Drug Discov Today. 2019 Feb;24(2):575-583
pubmed: 30342244
Nano Lett. 2019 Feb 13;19(2):658-665
pubmed: 30346182
Soft Matter. 2014 Dec 14;10(46):9237-47
pubmed: 25284271
Biomaterials. 2018 Mar;159:25-36
pubmed: 29309991
ACS Nano. 2016 Nov 22;10(11):10049-10057
pubmed: 27934074
Mol Pharm. 2019 Sep 3;16(9):3770-3779
pubmed: 31348660
Acta Biomater. 2017 Sep 1;59:269-282
pubmed: 28663143
ACS Appl Mater Interfaces. 2015 Apr 15;7(14):7584-98
pubmed: 25811662
Nano Lett. 2014 Oct 8;14(10):5577-83
pubmed: 25188744
Angew Chem Int Ed Engl. 2011 Nov 25;50(48):11417-20
pubmed: 22113800
Nano Lett. 2021 Apr 28;21(8):3418-3425
pubmed: 33827216
ACS Appl Mater Interfaces. 2016 Jun 1;8(21):13262-9
pubmed: 27176934
Adv Healthc Mater. 2014 Jun;3(6):906-15
pubmed: 24376098
Expert Opin Drug Deliv. 2015 Jan;12(1):129-42
pubmed: 25138827
Mol Pharm. 2019 Jun 3;16(6):2470-2480
pubmed: 30995065
Adv Mater. 2020 Feb;32(6):e1906024
pubmed: 31834662
Chem Asian J. 2019 Nov 4;14(21):3840-3844
pubmed: 31552698
Adv Drug Deliv Rev. 1997 Oct 13;28(1):25-42
pubmed: 10837563
Int J Pharm. 2019 May 1;562:313-320
pubmed: 30898641
Mol Pharm. 2010 Jun 7;7(3):863-9
pubmed: 20420443
Int J Pharm. 2020 Mar 15;577:119049
pubmed: 31982558
Adv Drug Deliv Rev. 2013 Jan;65(1):36-48
pubmed: 23036225
Molecules. 2020 Jan 30;25(3):
pubmed: 32019194
J Pharm Pharmacol. 2012 Oct;64(10):1394-402
pubmed: 22943170