Evaluation of hyperspectral imaging to quantify perfusion changes during the modified Allen test.
cuff occlusion test
hand perfusion
hemoglobin
hyperspectral imaging
modified Allen test
occlusion index
oxygenation
perfusion monitoring
reperfusion index
water content
Journal
Lasers in surgery and medicine
ISSN: 1096-9101
Titre abrégé: Lasers Surg Med
Pays: United States
ID NLM: 8007168
Informations de publication
Date de publication:
02 2022
02 2022
Historique:
received:
26
05
2021
accepted:
29
08
2021
pubmed:
21
9
2021
medline:
9
3
2022
entrez:
20
9
2021
Statut:
ppublish
Résumé
To evaluate the capability of hyperspectral imaging (HSI), a contact-less and noninvasive technology, to monitor perfusion changes of the hand during a modified Allen test (MAT) and cuff occlusion test. Furthermore, the study aimed at obtaining objective perfusion parameters of the hand. HSI of the hand was performed on 20 healthy volunteers with a commercially available HSI system during a MAT and a cuff occlusion test. Besides gathering red-green-blue (RGB) images, the perfusion parameters tissue hemoglobin index (THI), (superficial tissue) hemoglobin oxygenation (StO2), near-infrared perfusion (NIR), and tissue water index (TWI) were calculated for four different regions of interest on the hand. For the MAT, occlusion (OI; the ratio between the condition during occlusion and before occlusion) and reperfusion (RI; the ratio between the non-occlusion state and the prior occlusion state) indices were calculated for each perfusion parameter. All data were correlated to the clinical findings. False-color images showed visible differences between the various perfusion conditions during the MAT and cuff occlusion test. THI, StO2, and NIR behaved as expected from physiology, while TWI did not in the context of this study. During rest, mean THI, StO2, and NIR of the hand were 34 ± 2, 72 ± 9, and 61 ± 6, respectively. The RI for THI showed a roundabout threefold increase after reperfusion of both radial and ulnar artery and was thus, distinctly pronounced when compared with StO2 and NIR (~1.25). The OI was lowest for THI when compared with StO2 and NIR. HSI with its parameters THI, StO2, and NIR proved to be suitable to evaluate perfusion of the hand. By this, it could complement visual inspection during the MAT for evaluating the functionality of the superficial palmary arch before radial or ulnar artery harvest. The presented RI might deliver useful comparative values to detect pathological perfusion disorders at an early stage. As microcirculation monitoring is crucial for many medical issues, HSI shows potential to be used, besides further applications, in the monitoring of (free) flaps and transplants and microcirculation monitoring of critically ill patients.
Substances chimiques
Hemoglobins
0
Types de publication
Case Reports
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
245-255Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2021 The Authors. Lasers in Surgery and Medicine published by Wiley Periodicals LLC.
Références
Edelman GJ, Gaston E, van Leeuwen TG, Cullen PJ, Aalders MC. Hyperspectral imaging for non-contact analysis of forensic traces. Forensic Sci Int. 2012;223:28-39.
Feng YZ, Sun DW. Application of hyperspectral imaging in food safety inspection and control: a review. Crit Rev Food Sci Nutr. 2012;52:1039-58.
Schuler RL, Kish PE, Plese CA. Preliminary observations on the ability of hyperspectral imaging to provide detection and visualization of bloodstain patterns on black fabrics. J Forensic Sci. 2012;57:1562-9.
Calin MA, Coman T, Parasca SV, Bercaru N, Savastru R, Manea D. Hyperspectral imaging-based wound analysis using mixture-tuned matched filtering classification method. J Biomed Opt. 2015;20:046004.
Chiang N, Jain JK, Sleigh J, Vasudevan T. Evaluation of hyperspectral imaging technology in patients with peripheral vascular disease. J Vasc Surg. 2017;66:1192-201.
Chin JA, Wang EC, Kibbe MR. Evaluation of hyperspectral technology for assessing the presence and severity of peripheral artery disease. J Vasc Surg. 2011;54:1679-88.
Chin MS, Chappell AG, Giatsidis G, Perry DJ, Lujan-Hernandez J, Haddad A, et al. Hyperspectral imaging provides early prediction of random axial flap necrosis in a preclinical model. Plast Reconstr Surg. 2017;139:1285e-90e.
Daeschlein G, Langner I, Wild T, von Podevils S, Sicher C, Kiefer T, et al. Hyperspectral imaging as a novel diagnostic tool in microcirculation of wounds. Clin Hemorheol Microcirc. 2017;67:467-74.
Fabelo H, Ortega S, Ravi D, Kiran BR, Sosa C, Bulters D, et al. Spatio-spectral classification of hyperspectral images for brain cancer detection during surgical operations. PLoS One. 2018;13:e0193721.
Ferris DG, Lawhead RA, Dickman ED, Holtzapple N, Miller JA, Grogan S, et al. Multimodal hyperspectral imaging for the noninvasive diagnosis of cervical neoplasia. J Low Genit Tract Dis. 2001;5:65-72.
Gerstner AO, Laffers W, Schade G, Goke F, Martin R, Thies B. [Endoscopy of the larynx by hyperspectral imaging]. HNO. 2012;60:1047-52.
Grambow E, Dau M, Holmer A, Lipp V, Frerich B, Klar E, et al. Hyperspectral imaging for monitoring of perfusion failure upon microvascular anastomosis in the rat hind limb. Microvasc Res. 2018;116:64-70.
Grambow E, Dau M, Sandkühler NA, Leuchter M, Holmer A, Klar E, et al. Evaluation of peripheral artery disease with the TIVITA® Ttissue hyperspectral imaging camera system. Clin Hemorheol Microcirc. 2019;73:3-17.
Halicek M, Dormer JD, Little JV, Chen AY, Myers L, Sumer BD, et al. Hyperspectral imaging of head and neck squamous cell carcinoma for cancer margin detection in surgical specimens from 102 patients using deep learning. Cancers (Basel). 2019;11:11.
Halicek M, Little JV, Wang X, Chen AY, Fei B. Optical biopsy of head and neck cancer using hyperspectral imaging and convolutional neural networks. J Biomed Opt. 2019;24:1-9.
Holmer A, Tetschke F, Marotz J, Malberg H, Markgraf W, Tjiele C, et al. Oxygenation and perfusion monitoring with a hyperspectral camera system for chemical based tissue analysis of skin and organs. Physiol Meas. 2016;37:2064-78.
Kiyotoki S, Nishikawa J, Okamoto T, Hamabe K, Saito M, Goto A, et al. New method for detection of gastric cancer by hyperspectral imaging: a pilot study. J Biomed Opt. 2013;18:26010.
Kulcke A, Holmer A, Wahl P, Siemers F, Wild T, Daeschlein G. A compact hyperspectral camera for measurement of perfusion parameters in medicine. Biomed Tech (Berl). 2018;63:519-27.
Laffers W, Westermann S, Regeling B, Martin R, Thies B, Gerstner AO, et al. [Early recognition of cancerous lesions in the mouth and oropharynx: automated evaluation of hyperspectral image stacks]. HNO. 2016;64:27-33.
Martin R, Thies B, Gerstner AO. Hyperspectral hybrid method classification for detecting altered mucosa of the human larynx. Int J Health Geogr. 2012;11:21.
Panasyuk SV, Yang S, Faller DV, Ngo D, Lew RA, Freeman JE, et al. Medical hyperspectral imaging to facilitate residual tumor identification during surgery. Cancer Biol Ther. 2007;6:439-46.
Regeling B, Thies B, Gerstner AO, Westermann S, Müller NA, Bendix J, et al. Hyperspectral imaging using flexible endoscopy for laryngeal cancer detection. Sensors (Basel). 2016;16(8):1288.
Sucher R, Athanasios A, Köhler H, Wagner T, Brunotte M, Lederer A, et al. Hyperspectral Imaging (HSI) in anatomic left liver resection. Int J Surg Case Rep. 2019;62:108-11.
Sumpio BJ, Citoni G, Chin JA, Sumpio BE. Use of hyperspectral imaging to assess endothelial dysfunction in peripheral arterial disease. J Vasc Surg. 2016;64:1066-73.
Thiem DGE, Frick RW, Goetze E, Gielisch M, Al-Nawas B, Kämmerer PW. Hyperspectral analysis for perioperative perfusion monitoring-a clinical feasibility study on free and pedicled flaps. Clin Oral Investig. 2021;25(3):933-45.
Backman V, Wallace MB, Perelman LT, Arendt JT, Gurjar R, Müller MG, et al. Detection of preinvasive cancer cells. Nature. 2000;406:35-6.
Pierce MC, Schwarz RA, Bhattar VS, Mondrik S, Williams MD, Lee JJ, et al. Accuracy of in vivo multimodal optical imaging for detection of oral neoplasia. Cancer Prev Res (Phila). 2012;5:801-9.
Fei B, Lu G, Wang X, Zhang H, Little JV, Patel MR, et al. Label-free reflectance hyperspectral imaging for tumor margin assessment: a pilot study on surgical specimens of cancer patients. J Biomed Opt. 2017;22:1-7.
Jansen-Winkeln B, Maktabi M, Takoh JP, Rabe SM, Barberio M, Köhler H, et al. [Hyperspectral imaging of gastrointestinal anastomoses]. Chirurg. 2018;89:717-25.
Schulz T, Marotz J, Stukenberg A, Reumuth G, Houschyar KS, Siemers F. [Hyperspectral imaging for postoperative flap monitoring of pedicled flaps]. Handchir Mikrochir Plast Chir. 2020;52:316-24.
Burchell HB, Edgar V. ALLEN, 1900-1961. Trans Assoc Am Physicians. 1962;75:13-6.
Fuhrman TM, Pippin WD, Talmage LA, Reilley TE. Evaluation of collateral circulation of the hand. J Clin Monit. 1992;8:28-32.
Abdullakutty A, Bajwa MS, Patel S, D'Souza J. Clinical audit and national survey on the assessment of collateral circulation before radial forearm free flap harvest. J Craniomaxillofac Surg. 2017;45:108-12.
Abu-Omar Y, Mussa S, Anastasiadis K, Steel S, Hands L, Taggart DP. Duplex ultrasonography predicts safety of radial artery harvest in the presence of an abnormal Allen test. Ann Thorac Surg. 2004;77:116-9.
Bartella AK, Flick N, Kamal Met al. Hand perfusion in patients with physiological or pathological Allen's tests. J Reconstr Microsurg. 2019;35:182-8.
Gokhroo R, Bisht D, Gupta S, Kishor K, Ranwa B. palmary arch anatomy: Ajmer Working Group classification. Vascular. 2016;24:31-6.
Habib J, Baetz L, Satiani B. Assessment of collateral circulation to the hand prior to radial artery harvest. Vasc Med. 2012;17:352-61.
Hoffman RD, Danos DM, Lin SJ, Lau FH, Kim PS. Prevalence of accessory branches and other anatomical variations in the radial artery encountered during radial forearm flap harvest: a systematic review and meta-analysis. J Reconstr Microsurg. 2020;36(9):651-9.
Oettlé AC, van Niekerk A, Boon JM, Meiring JH. Evaluation of Allen's test in both arms and arteries of left and right-handed people. Surg Radiol Anat. 2006;28:3-6.
Yadava OP, Dinda AK, Mohanty BK, Mishra R, Ahlawat V, Kundu A. Is radial artery Doppler scanning mandatory for use as coronary bypass conduit? Asian Cardiovasc Thorac Ann. 2015;23:822-7.
Bertino G, Lepenne Y, Tinelli C, Giordano L, Cacciola S, Di Santo D, et al. Radial vs ulnar forearm flap: a preliminary study of donor site morbidity. Acta Otorhinolaryngol Ital. 2019;39:322-8.
de Vicente JC, Espinosa C, Rúa-Gonzálvez L, Rodríguez-Santamarta T, Alonso M. Hand perfusion following radial or ulnar forearm free flap harvest for oral cavity reconstruction: a prospective study. Int J Oral Maxillofac Surg. 2020;49:1402-7.
Chung J, Ji SH, Jang YE, Kim EH, Lee JH, Kim JT, et al. Evaluation of different near-infrared spectroscopy devices for assessing tissue oxygenation with a vascular occlusion test in healthy volunteers. J Vasc Res. 2020;57:341-7.
Rosenberry R, Munson M, Chung S, Samuel TJ, Patik J, Tucker WJ, et al. Age-related microvascular dysfunction: novel insight from near-infrared spectroscopy. Exp Physiol. 2018;103:190-200.
Mayeur C, Campard S, Richard C, Teboul JL. Comparison of four different vascular occlusion tests for assessing reactive hyperemia using near-infrared spectroscopy. Crit Care Med. 2011;39:695-701.
Marotz J, Kulcke A, Siemers F, Cruz D, Aljowder A, Promny D, et al. Extended perfusion parameter estimation from hyperspectral imaging data for bedside diagnostic in medicine. Molecules. 2019;24(22):4164.
Holmer A, Marotz J, Wahl P, Dau M, Kämmerer PW. Hyperspectral imaging in perfusion and wound diagnostics - methods and algorithms for the determination of tissue parameters. Biomed Tech (Berl). 2018;63:547-56.
Linek M, Felicio-Briegel A, Freymüller C, Rühm A, Sroka R, Volgger V. Investigation on hyperspectral imaging derived indices for perfusion monitoring. Biophotonics Congress 2021 (12-16 April 2021). Boudoux C, Maitland K, Hendon C, Wojtkowski M, Quinn K, Schanne-Klein M, Durr N, Elson D, Cichos F, Oddershede L, Emiliani V, Maragò O, Nic Chormaic S, Pégard N, Gibbs S, Vinogradov S, Niedre M, Samkoe K, Devor A, Peterka D, Blinder P, and Buckley E, editors. OSA Technical Digest, paper OM1E.3. Optical Society of America; 2021.
Bashkatov AN, Genina EA, Kochubey VI, Tuchin VV. Optical properties of human skin, subcutaneous and mucous tissues in the wavelength range from 400 to 2000 nm. J Phys D Appl Phys. 2005;38(15):2543-55.
Kohonen M, Teerenhovi O, Terho T, Laurikka J, Tarkka M. Non-harvestable radial artery. A bilateral problem? Interact Cardiovasc Thorac Surg. 2008;7:797-800.
Huber W, Zanner R, Schneider G, Schmid R, Lahmer T. Assessment of regional perfusion and organ function: less and non-invasive techniques. Front Med (Lausanne). 2019;6:50.
Lopez Silva SM, Dotor Castilla ML, Silveira Martin JP. Near-infrared transmittance pulse oximetry with laser diodes. J Biomed Opt. 2003;8:525-33.
Mendelson Y. Pulse oximetry: theory and applications for noninvasive monitoring. Clin Chem. 1992;38:1601-7.
Rosenberry R, Nelson MD. Reactive hyperemia: a review of methods, mechanisms, and considerations. Am J Physiol Regul Integr Comp Physiol. 2020;318:R605-18.
Fronek A, King D. An objective sequential compression test to evaluate the patency of the radial and ulnar arteries. J Vasc Surg. 1985;2:450-2.
Johnson WH, 3rd, Cromartie RS, 3rd, Arrants JE, Wuamett JD, et al. Simplified method for candidate selection for radial artery harvesting. Ann Thorac Surg. 1998;65:1167.
Jarvis MA, Jarvis CL, Jones PR, Spyt TJ. Reliability of Allen's test in selection of patients for radial artery harvest. Ann Thorac Surg. 2000;70:1362-5.
Bowen WJ. The absorption spectra and extinction coefficients of myoglobin. J Biol Chem. 1949;179:235-45.
Sweeny L, Topf M, Wax MK, Rosenthal EL, Greene BJ, Heffelfinger R, et al. Shift in the timing of microvascular free tissue transfer failures in head and neck reconstruction. Laryngoscope. 2020;130:347-53.
Chang EI, Zhang H, Liu J, Yu P, Skoracki RJ, Hanasono MM. Analysis of risk factors for flap loss and salvage in free flap head and neck reconstruction. Head Neck. 2016;38(Suppl 1):E771-5.
Oranges CM, Ling B, Tremp M, Wettstein R, Kalbermatten DF, Schaefer DJ. Comparison of anterolateral thigh and radial forearm free flaps in head and neck reconstruction. In Vivo. 2018;32:893-7.
Reiter M, Baumeister P. Reconstruction of laryngopharyngectomy defects: comparison between the supraclavicular artery island flap, the radial forearm flap, and the anterolateral thigh flap. Microsurgery. 2019;39:310-5.
Kääriäinen M, Halme E, Laranne J. Modern postoperative monitoring of free flaps. Curr Opin Otolaryngol Head Neck Surg. 2018;26:248-53.
Kohlert S, Quimby AE, Saman M, Ducic Y. Postoperative free-flap monitoring techniques. Semin Plast Surg. 2019;33:13-6.