Avidin-Conjugated Nanofibrillar Cellulose Hydrogel Functionalized with Biotinylated Fibronectin and Vitronectin Promotes 3D Culture of Fibroblasts.

Animals Avidin Cellulose Fibroblasts Fibronectins Hydrogels Mice Vitronectin

Journal

Biomacromolecules
ISSN: 1526-4602
Titre abrégé: Biomacromolecules
Pays: United States
ID NLM: 100892849

Informations de publication

Date de publication:
11 10 2021
Historique:
pubmed: 21 9 2021
medline: 25 2 2023
entrez: 20 9 2021
Statut: ppublish

Résumé

The future success of physiologically relevant three-dimensional (3D) cell/tissue models is dependent on the development of functional biomaterials, which can provide a well-defined 3D environment instructing cellular behavior. To establish a platform to produce tailored hydrogels, we conjugated avidin (Avd) to anionic nanofibrillar cellulose (aNFC) and demonstrated the use of the resulting Avd-NFC hydrogel for 3D cell culture, where Avd-NFC allows easy functionalization

Identifiants

DOI: 10.1021/acs.biomac.1c00579 PMID: 34542997
pubmed: 34542997
doi: 10.1021/acs.biomac.1c00579
doi:

Substances chimiques

Fibronectins 0
Hydrogels 0
Vitronectin 0
Avidin 1405-69-2
Cellulose 9004-34-6

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4122-4137

Auteurs

Jenni Leppiniemi (J)

Faculty of Medicine and Health Technology and BioMediTech, Tampere University, FI-33014 Tampere, Finland.
ORCID: 0000-0002-7225-1648

Zeeshan Mutahir (Z)

Faculty of Medicine and Health Technology and BioMediTech, Tampere University, FI-33014 Tampere, Finland.
School of Biochemistry and Biotechnology, University of the Punjab, 54590 Lahore, Pakistan.

Alexander Dulebo (A)

JPK BioAFM Business, Bruker Nano GmbH, Am Studio 2D, 12489 Berlin, Germany.

Piia Mikkonen (P)

UPM-Kymmene Corporation, Alvar Aallon Katu 1, 00101 Helsinki, Finland.

Markus Nuopponen (M)

UPM-Kymmene Corporation, Alvar Aallon Katu 1, 00101 Helsinki, Finland.

Paula Turkki (P)

Faculty of Medicine and Health Technology and BioMediTech, Tampere University, FI-33014 Tampere, Finland.
Fimlab Laboratories, Biokatu 4, FI-33520 Tampere, Finland.

Vesa P Hytönen (VP)

Faculty of Medicine and Health Technology and BioMediTech, Tampere University, FI-33014 Tampere, Finland.
Fimlab Laboratories, Biokatu 4, FI-33520 Tampere, Finland.
ORCID: 0000-0002-9357-1480

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Avidin-Conjugated Nanofibrillar Cellulose...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Glycoprotéines › Avidine › Avidin-Conjugated Nanofibrillar Cellulose...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomédicaux et dentaires › Polymères › Biopolymères › Cellulose › Avidin-Conjugated Nanofibrillar Cellulose...
questionsmedicales.fr › Cellules › Cellules du tissu conjonctif › Fibroblastes › Avidin-Conjugated Nanofibrillar Cellulose...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Fibronectines › Avidin-Conjugated Nanofibrillar Cellulose...
questionsmedicales.fr › Préparations pharmaceutiques › Colloïdes › Gels › Hydrogels › Avidin-Conjugated Nanofibrillar Cellulose...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Avidin-Conjugated Nanofibrillar Cellulose...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Scléroprotéines › Protéines de la matrice extracellulaire › Vitronectine › Avidin-Conjugated Nanofibrillar Cellulose...