Immunobiology of the Classical Lancefield Group A Streptococcal Carbohydrate Antigen.
GlcNAc
Lancefield antigen
Streptococcus pyogenes
autoimmunity
cell wall
group A Streptococcus
group A carbohydrate
rheumatic heart disease
vaccine
virulence factor
Journal
Infection and immunity
ISSN: 1098-5522
Titre abrégé: Infect Immun
Pays: United States
ID NLM: 0246127
Informations de publication
Date de publication:
16 11 2021
16 11 2021
Historique:
pubmed:
21
9
2021
medline:
15
12
2021
entrez:
20
9
2021
Statut:
ppublish
Résumé
Group A Streptococcus (GAS) is a preeminent human bacterial pathogen causing hundreds of millions of infections each year worldwide. In the clinical setting, the bacterium is easily identified by a rapid antigen test against the group A carbohydrate (GAC), a polysaccharide that comprises 30 to 50% of the GAS cell wall by weight. Originally described by Rebecca Lancefield in the 1930s, GAC consists of a polyrhamnose backbone and a
Identifiants
pubmed: 34543125
doi: 10.1128/IAI.00292-21
pmc: PMC8594609
doi:
Substances chimiques
Antigens, Bacterial
0
Polysaccharides, Bacterial
0
Virulence Factors
0
streptococcal polysaccharide group A
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0029221Subventions
Organisme : NIAID NIH HHS
ID : R01 AI077780
Pays : United States
Organisme : NIGMS NIH HHS
ID : T32 GM008666
Pays : United States
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